{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T10:58:12Z","timestamp":1775473092663,"version":"3.50.1"},"reference-count":26,"publisher":"Medical Association of Zenica-Doboj","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2021,6,1]]},"abstract":"<jats:p>&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Aim &amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt;To provide evidence regarding the effectiveness of aripiprazole in improving penile erection with a therapeutic strategy of&amp;lt;br \/&amp;gt;add-on or switching therapy in patients with schizophrenia.&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Methods&amp;lt;br \/&amp;gt;&amp;lt;\/strong&amp;gt;PubMed, Cochrane, Clinical Key, ProQuest, EBSCOhost, and ScienceDirect were searched for any design study that&amp;lt;br \/&amp;gt;evaluated aripiprazole only or versus control (placebo or other antipsychotic) for erectile dysfunction in patients with schizophrenia. Three studies were identified and analysed from 295 initial articles. Data were then extracted from the studies and summarized descriptively.&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Results&amp;lt;\/strong&amp;gt; &amp;lt;br \/&amp;gt;Two hundred ninety-five articles were screened, and three studies were identified and eventually selected. After the add-on or switching antipsychotic therapy to aripiprazole, the prevalence of erectile dysfunction and the score of erectile dysfunction or penile erection assessed by Nagoya and Sexual Function Questionnaire (NSFQ) and Arizona Sexual Experience Scale (ASEX) decreased.&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Conclusion&amp;lt;\/strong&amp;gt; &amp;lt;br \/&amp;gt;Aripiprazole was effective to improve penile erectile function in patients with schizophrenia. The therapeutic strategy is&amp;lt;br \/&amp;gt;adjunctive treatment or switching therapy to aripiprazole.&amp;lt;\/p&amp;gt;<\/jats:p>","DOI":"10.17392\/1360-21","type":"journal-article","created":{"date-parts":[[2024,4,21]],"date-time":"2024-04-21T10:28:16Z","timestamp":1713695296000},"page":"432-437","source":"Crossref","is-referenced-by-count":1,"title":["The role of aripiprazole in improvement of penile erection in schizophrenia patients with erectile dysfunction"],"prefix":"10.17392","volume":"18","author":[{"given":"Debby","family":"Handayati Harahap","sequence":"first","affiliation":[{"name":"Public Health, and Nursing, Universitas Gadjah Mada","place":["Yogyakarta,Indonesia"],"department":["Doctoral Program"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8467-1570","authenticated-orcid":false,"given":"Carla","family":"Raymondalexas Marchira","sequence":"additional","affiliation":[{"name":"Public Health, and Nursing, Universitas Gadjah Mada","place":["Yogyakarta,Indonesia"],"department":["Department of Psychiatry"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eti","family":"Nurwening Solikhah","sequence":"additional","affiliation":[{"name":"Public Health, and Nursing, Universitas Gadjah Mada","place":["Yogyakarta,Indonesia"],"department":["Department of Pharmacology"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dicky","family":"Moch Rizal","sequence":"additional","affiliation":[{"name":"Public Health, and Nursing, Universitas Gadjah Mada","place":["Yogyakarta,Indonesia"],"department":["Department of Physiology"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"49509","published-online":{"date-parts":[[2021,6,1]]},"reference":[{"key":"ref1","first-page":"86","author":"MOwenM","year":"2016","unstructured":"Owen MJ, Sawa A, Mortensen PB. 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Aripiprazole, a drug that \ndisplays partial agonism and functional selectivity. \nCurr Neuropharmacol 2017; 15:1192-207.","journal-title":"Curr Neuropharmacol"},{"key":"ref12","first-page":"244","article-title":"Change in sexual dysfunction with aripiprazole: a switching or add-on study","author":"AMirA","year":"2008","unstructured":"Mir A, Shivakumar K, Williamson RJ, McAlli-\nster V, O'Keane V, Aitchison KJ. Change in sexual \ndysfunction with aripiprazole: a switching or add-on \nstudy. J Psychopharmacol 2008; 22:244-53.","journal-title":"J Psychopharmacol"},{"issue":"8","key":"ref13","first-page":"95","article-title":"The effect of antipsychotic medication on sexual function and serum prolactin levels in community-treated schizophrenic patients: results from the Schizophrenia Trial of Aripiprazole (STAR) study (NCT00237913)","author":"LHanssensL","year":"2008","unstructured":"Hanssens L, L'Italien G, Loze JY, Marcus RN, \nPans M, Kerselaers W. 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