{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T15:49:37Z","timestamp":1776959377532,"version":"3.51.4"},"reference-count":0,"publisher":"Medical Association of Zenica-Doboj","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2024,9,1]]},"abstract":"<jats:p>&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Aim&amp;lt;\/strong&amp;gt; To evaluate diagnostic reliability of accessible laboratory findings in recognition of acute appendicitis (AA).&amp;amp;nbsp;&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Methods&amp;lt;\/strong&amp;gt; A retrospective study included children aged 0-15 years with abdominal pain that lasted less than 5 days with at least two of the signs\/symptoms - abdominal pain, tenderness of the lower right quadrant of the abdomen, &amp;quot;return&amp;quot; sensitivity of the abdomen to palpation, loss of appetite, nausea, vomiting, body temperature&amp;amp;gt;37.2&amp;amp;deg;C. Values of procalcitonin (PCT), C-reactive protein (CRP) and the leukocyte count were analyzed in the peripheral blood. &amp;amp;nbsp;&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Results&amp;lt;\/strong&amp;gt; Among 114 children, 63 (58.2%) were boys and 50 (41.8%) girls; median age of 9.5 years. Elevated values of PCT were found in 74 (65.5%), CRP in 94 (83.1%), and leukocytes in 78 (69%) (65%) children. Almost uniform significance in the recognition of AA was found for pathological values of PCT and CRP with sensitivity of 65% and 83% and diagnostic accuracy of 63% and 59%, respectively, but somewhat lower sensitivity for leukocytes, 61%. A very high predictive value of 98% for PCT and CRP, and PCT with leukocytes was found; CRP with leukocytes had a negative predictive value of 100%.&amp;amp;nbsp;&amp;lt;br \/&amp;gt;&amp;lt;strong&amp;gt;Conclusion&amp;lt;\/strong&amp;gt; PCT values have significant sensitivity, specificity and diagnostic accuracy in recognizing AA, while CRP and leukocytes, with high sensitivity, as non-specific markers can be a significant support for clinical assessment in the timely diagnosis of AA.&amp;lt;\/p&amp;gt;<\/jats:p>","DOI":"10.17392\/1712-21-02","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T07:01:14Z","timestamp":1721804474000},"page":"315-320","source":"Crossref","is-referenced-by-count":1,"title":["Diagnostic value of procalcitonin, C-reactive protein and leukocyte count in detecting acute appendicitis in paedi-atric patients - a single center experience"],"prefix":"10.17392","volume":"21","author":[{"given":"Sanimir","family":"Suljendi\u0107","sequence":"first","affiliation":[{"name":"Clinic for Children's Diseases, University Clinical Centre Tuzla"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Almira","family":"\u0106osi\u0107ki\u0107","sequence":"additional","affiliation":[{"name":"Clinic for Children's Diseases, University Clinical Centre Tuzla"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0648-2955","authenticated-orcid":false,"given":"Azra","family":"Had\u017ei\u0107-Ke\u010dalovi\u0107","sequence":"additional","affiliation":[{"name":"Cantonal Hospital ''Dr. Irfan Ljubijanki\u0107'' Biha\u0107"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis","family":"\u017digi\u0107","sequence":"additional","affiliation":[{"name":"Clinic for Children's Diseases, University Clinical Centre Tuzla"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"49509","published-online":{"date-parts":[[2024,9,1]]},"container-title":["Medicinski Glasnik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medicinskiglasnik.ba\/article\/1905\/pdf\/download","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicinskiglasnik.ba\/article\/1905\/pdf\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:45:16Z","timestamp":1775468716000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicinskiglasnik.ba\/article\/id\/466\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,1]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,9,1]]},"published-print":{"date-parts":[[2024,9,1]]}},"URL":"https:\/\/doi.org\/10.17392\/1712-21-02","archive":["Internet Archive"],"relation":{},"ISSN":["1840-0132","1840-0132"],"issn-type":[{"value":"1840-0132","type":"electronic"},{"value":"1840-0132","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9,1]]}}}