{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:59:16Z","timestamp":1785419956450,"version":"3.56.0"},"reference-count":0,"publisher":"Medical Association of Zenica-Doboj","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2025,8,25]]},"abstract":"&lt;div&gt;\n&lt;pre&gt;&lt;strong&gt;&lt;span lang=&quot;EN-US&quot;&gt;Aim&lt;br \/&gt;&lt;\/span&gt;&lt;\/strong&gt;&lt;span lang=&quot;EN-US&quot;&gt;To evaluate the clinical course and outcomes of oligoarticular juvenile idiopathic arthritis(JIA) patients from 2003 to 2021, identifying factors linked to severe disease and complications.&lt;\/span&gt;&lt;\/pre&gt;\n&lt;\/div&gt;\n&lt;div&gt;\n&lt;pre&gt;&lt;strong&gt;&lt;span lang=&quot;EN-US&quot;&gt;Methods&lt;\/span&gt;&lt;\/strong&gt;&lt;\/pre&gt;\n&lt;\/div&gt;\n&lt;div&gt;\n&lt;pre&gt;&lt;span lang=&quot;EN-US&quot;&gt;We analyzed 208 oligoarticular JIA patients followed at Cerrahpa\u015fa Medical School, using medical records. Continuous variables were compared with the Mann-Whitney U test, and logistic regression was applied to identify predictors of severe disease and damage.&lt;\/span&gt;&lt;\/pre&gt;\n&lt;\/div&gt;\n&lt;div&gt;\n&lt;pre&gt;&lt;strong&gt;&lt;span lang=&quot;EN-US&quot;&gt;Results&lt;\/span&gt;&lt;\/strong&gt;&lt;\/pre&gt;\n&lt;\/div&gt;\n&lt;div&gt;\n&lt;pre&gt;&lt;span lang=&quot;EN-US&quot;&gt;Among 208 patients (68.75% female), the average treatment duration was 45 months. The knee was the most affected joint (82.6%), followed by the ankle (50.4%). The initial mean Juvenil Arthritis Disease Activity Score (JADAS) score was 18, decreasing to 3 at the last visit. Juvenile Arthritis Damage Index (JADI) score averaged 0.64. Limited range of motion was observed in 34.13% patients. Uveitis was the most common extra-articular complication (14.9%), with higher biologic use in these patients (p&amp;lt;0.001). Disease severity correlated with initial and final JADAS (p&amp;lt;0.001) and JADI (p&amp;lt;0.001). Regression analysis linked elbow involvement (p=0.000) and adalimumab use (p=0.001) to disease sequelae. MEFV gene mutations were found in 10.9% of patients. Based on Wallace criteria, 85% were in remission with medication, 6.25% had inactive disease, and 8.6% achieved drug-free remission.&lt;\/span&gt;&lt;\/pre&gt;\n&lt;\/div&gt;\n&lt;div&gt;\n&lt;pre&gt;&lt;strong&gt;&lt;span lang=&quot;EN-US&quot;&gt;Conclusion: &lt;\/span&gt;&lt;\/strong&gt;&lt;span lang=&quot;EN-US&quot;&gt;Oligoarticular JIA generally has a mild course and good prognosis. However, elbow involvement and biologic use are associated with more severe disease and sequelae. Uveitis is the most common extra-articular complication.&lt;\/span&gt;&lt;\/pre&gt;\n&lt;\/div&gt;\n&lt;div&gt;\n&lt;pre&gt;&lt;strong&gt;&lt;span lang=&quot;EN-US&quot;&gt;Keywords: &lt;\/span&gt;&lt;\/strong&gt;&lt;span lang=&quot;EN-US&quot;&gt;arthritis, biologics, damage, oligoarticular JIA&lt;\/span&gt;&lt;\/pre&gt;\n&lt;\/div&gt;<\/jats:p>","DOI":"10.17392\/1905-22-02","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T11:52:48Z","timestamp":1757591568000},"source":"Crossref","is-referenced-by-count":0,"title":["The long-term follow up of patients with oligoarticular juvenile idiopathic arthritis: a single center experience."],"prefix":"10.17392","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8046-3907","authenticated-orcid":false,"given":"Aytan","family":"Aliyeva","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01dzn5f42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2400-6955","authenticated-orcid":false,"given":"Amra","family":"Adrovic","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01dzn5f42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6963-9668","authenticated-orcid":false,"given":"Fatih","family":"Aslak","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01dzn5f42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0101-9585","authenticated-orcid":false,"given":"Oya","family":"Koker","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01dzn5f42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7834-4909","authenticated-orcid":false,"given":"Mehmet","family":"Yildiz","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01dzn5f42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5365-3457","authenticated-orcid":false,"given":"Sezgin","family":"Sahin","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01dzn5f42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8459-2872","authenticated-orcid":false,"given":"Kenan","family":"Barut","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01dzn5f42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1125-7720","authenticated-orcid":false,"given":"Ozgur","family":"Kasapcopur","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/01dzn5f42","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"49509","published-online":{"date-parts":[[2025,8,25]]},"container-title":["Medicinski Glasnik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medicinskiglasnik.ba\/article\/2278\/pdf\/download","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicinskiglasnik.ba\/article\/2278\/pdf\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:45:32Z","timestamp":1775468732000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicinskiglasnik.ba\/article\/id\/523\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,25]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,8,25]]},"published-print":{"date-parts":[[2025,8,25]]}},"URL":"https:\/\/doi.org\/10.17392\/1905-22-02","archive":["Internet Archive"],"relation":{},"ISSN":["1840-2445","1840-0132"],"issn-type":[{"value":"1840-2445","type":"electronic"},{"value":"1840-0132","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,25]]}}}