{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:09:16Z","timestamp":1785434956746,"version":"3.56.0"},"reference-count":0,"publisher":"Medical Association of Zenica-Doboj","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2025,8,25]]},"abstract":"<jats:p>&amp;lt;p class=&amp;quot;Standard&amp;quot; style=&amp;quot;line-height: 200%;&amp;quot;&amp;gt;&amp;lt;strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt;ABSTRACT&amp;lt;\/span&amp;gt;&amp;lt;\/strong&amp;gt;&amp;lt;\/p&amp;gt;\n&amp;lt;p class=&amp;quot;Standard&amp;quot; style=&amp;quot;line-height: 200%;&amp;quot;&amp;gt;&amp;lt;strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif;&amp;quot;&amp;gt;Aim&amp;lt;\/span&amp;gt;&amp;lt;\/strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif;&amp;quot;&amp;gt; This study compared the extent of coronary artery calcification in patients &amp;lt;span style=&amp;quot;color: #202124;&amp;quot;&amp;gt;with and without type 2 diabetes mellitus (T2DM) using Coronary Computed Tomography Angiography (CCTA).&amp;lt;\/span&amp;gt;&amp;lt;\/span&amp;gt;&amp;lt;\/p&amp;gt;\n&amp;lt;p class=&amp;quot;Standard&amp;quot; style=&amp;quot;line-height: 200%;&amp;quot;&amp;gt;&amp;lt;strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt;Methods &amp;lt;\/span&amp;gt;&amp;lt;\/strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt;This retrospective, observational cohort study included 107 patients who underwent CCTA at the Clinical Centre of the University of Sarajevo between July and December 2024. Patients were divided into two groups: those with T2DM (n=51) and those without T2DM (n=56). Laboratory parameters, demographic data, and calcium scores were analysed. The calcium score was categorised into six groups based on cardiovascular &amp;lt;\/span&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif;&amp;quot;&amp;gt;risk and the comparison was made using appropriate statistical analysis. &amp;lt;\/span&amp;gt;&amp;lt;\/p&amp;gt;\n&amp;lt;p class=&amp;quot;Standard&amp;quot; style=&amp;quot;line-height: 200%;&amp;quot;&amp;gt;&amp;lt;strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt;Results&amp;lt;\/span&amp;gt;&amp;lt;\/strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt; Patients with T2DM had significantly higher calcium &amp;lt;\/span&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif;&amp;quot;&amp;gt;scores than &amp;lt;span style=&amp;quot;color: #202124;&amp;quot;&amp;gt;non-diabetic patients (p=0.0001). In the T2DM group, 35.3% of patients had a calcium score &amp;amp;gt;400, indicating high cardiovascular risk. Patients without diabetes were more frequently classified into lower-risk categories (p=0.0001). A significant correlation was found between calcium score and age (r=0.442, p=0.001) and gender (r=-0.218, p=0.024), with men having higher calcium scores. Additionally, total cholesterol, LDL, and uric acid levels were significantly higher in diabetic patients (p=0.005; p=0.025; p=0.03, respectively).&amp;lt;\/span&amp;gt;&amp;lt;\/span&amp;gt;&amp;lt;\/p&amp;gt;\n&amp;lt;p class=&amp;quot;Standard&amp;quot; style=&amp;quot;line-height: 200%;&amp;quot;&amp;gt;&amp;lt;strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt;Conclusion&amp;lt;\/span&amp;gt;&amp;lt;\/strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt; This study confirms a strong association between T2DM and increased coronary artery calcification. Age and male gender are significant predictors of higher calcium scores. Further research is needed to explore these relationships, particularly within the Bosnian population.&amp;lt;\/span&amp;gt;&amp;lt;\/p&amp;gt;\n&amp;lt;p class=&amp;quot;Standard&amp;quot; style=&amp;quot;line-height: 200%;&amp;quot;&amp;gt;&amp;lt;strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt;Keywords &amp;lt;\/span&amp;gt;&amp;lt;\/strong&amp;gt;&amp;lt;span lang=&amp;quot;EN-GB&amp;quot; style=&amp;quot;font-family: &amp;#039;Times New Roman&amp;#039;,serif; color: #202124;&amp;quot;&amp;gt;Coronary angiography, coronary artery calcification, coronary disease, diabetes mellitus type 2&amp;lt;\/span&amp;gt;&amp;lt;\/p&amp;gt;<\/jats:p>","DOI":"10.17392\/1972-22-02","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T08:09:50Z","timestamp":1754035790000},"source":"Crossref","is-referenced-by-count":1,"title":["Comparison of coronary artery calcium scores between patients with and without type 2 diabetes"],"prefix":"10.17392","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7240-7940","authenticated-orcid":false,"given":"Mirza","family":"Babi\u0107","sequence":"first","affiliation":[{"name":"Cantonal hospital \"Dr Irfan Ljubijanki\u0107\"","place":["Biha\u0107,Bosnia and Herzegovina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5298-1961","authenticated-orcid":false,"given":"Zarina","family":"Babi\u0107 Ju\u0161i\u0107","sequence":"additional","affiliation":[{"name":"Cantonal hospital \"Dr Irfan Ljubijanki\u0107\"","place":["Biha\u0107,Bosnia and Herzegovina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7021-7027","authenticated-orcid":false,"given":"Sabina","family":"Prevljak","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/019bz1656","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0219-0867","authenticated-orcid":false,"given":"Fuad","family":"Zuki\u0107","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/019bz1656","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4391-5226","authenticated-orcid":false,"given":"Minela","family":"Be\u0107irovi\u0107","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0474ygz28","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7012-8064","authenticated-orcid":false,"given":"Amir","family":"Be\u0107irovi\u0107","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0474ygz28","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3999-6521","authenticated-orcid":false,"given":"Admir","family":"Abdi\u0107","sequence":"additional","affiliation":[{"name":"Cantonal hospital \"Dr Irfan Ljubijanki\u0107\"","place":["Biha\u0107,Bosnia and Herzegovina"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4134-987X","authenticated-orcid":false,"given":"Emir","family":"Be\u0107irovi\u0107","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/0474ygz28","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"49509","published-online":{"date-parts":[[2025,8,25]]},"container-title":["Medicinski Glasnik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medicinskiglasnik.ba\/article\/2340\/pdf\/download","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicinskiglasnik.ba\/article\/2340\/pdf\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:45:30Z","timestamp":1775468730000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicinskiglasnik.ba\/article\/id\/517\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,25]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2025,8,25]]},"published-print":{"date-parts":[[2025,8,25]]}},"URL":"https:\/\/doi.org\/10.17392\/1972-22-02","archive":["Internet Archive"],"relation":{},"ISSN":["1840-2445","1840-0132"],"issn-type":[{"value":"1840-2445","type":"electronic"},{"value":"1840-0132","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,25]]}}}