{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T09:57:04Z","timestamp":1785405424690,"version":"3.56.0"},"reference-count":0,"publisher":"Medical Association of Zenica-Doboj","issue":"1","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2026,2,27]]},"abstract":"<jats:p>&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Aim&amp;lt;\/strong&amp;gt; Many studies have demonstrated that over half of the World&amp;#039;s population is infected with &amp;lt;em&amp;gt;Helicobacter pylori (H. pylori)&amp;lt;\/em&amp;gt;. To evaluate the current &amp;lt;em&amp;gt;H. pylori&amp;lt;\/em&amp;gt; seroprevalence in Bosnia and Herzegovina (B&amp;amp;amp;H), &amp;lt;em&amp;gt;H. pylori &amp;lt;\/em&amp;gt;antibodies (immunoglobulin G, IgG) from patients with suspected presence were analyzed.&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Methods &amp;lt;\/strong&amp;gt;In total, 201\/471 (42.7%) males and 270\/471 (57.3%) females were enrolled between June 2024 and July 2024. They were tested using the enzyme-linked immunosorbent assay (ELISA) method.&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Results&amp;lt;\/strong&amp;gt; The overall seroprevalence of &amp;lt;em&amp;gt;H. pylori&amp;lt;\/em&amp;gt; infection was 214 (out of 471; 45.4%) and did not differ in relation to sex. The seroprevalence rate of &amp;lt;em&amp;gt;H. pylori&amp;lt;\/em&amp;gt; was highest in the 50&amp;amp;ndash;69 age group, 81 (out of 137; 59.1%; 95% CI: 2.2&amp;amp;ndash;5.6), followed by the &amp;amp;ge;70 age group, 17 (out of 31; 54.8%; CI: 2.0&amp;amp;ndash;6.7), and the 30&amp;amp;ndash;49 age group, 101 (out of 219; 46.1%; 95% CI: 1.7&amp;amp;ndash;4.3). The lowest seroprevalence rate was in the younger age group (&amp;amp;le;29) with 15 (out of 84; 17.8%). Older age groups were more likely to be &amp;lt;em&amp;gt;H. pylori&amp;lt;\/em&amp;gt; positive and equivocal, while younger age groups negative for &amp;lt;em&amp;gt;H. pylori&amp;lt;\/em&amp;gt; infection.&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;Conclusion &amp;lt;\/strong&amp;gt;This single-center study is the first study providing information on the &amp;lt;em&amp;gt;H. pylori&amp;lt;\/em&amp;gt; seroprevalence in the B&amp;amp;amp;H population and investigating its association with age and sex. Further research is needed to explore other risk factors and to develop effective ways to reduce the burden of this infection.&amp;lt;\/p&amp;gt;<\/jats:p>","DOI":"10.17392\/1974-23-01","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T10:54:38Z","timestamp":1772189678000},"page":"58-62","source":"Crossref","is-referenced-by-count":0,"title":["Seroprevalence of Helicobacter pylori in Bosnia and Herzegovina: a single-center cross-sectional study"],"prefix":"10.17392","volume":"23","author":[{"given":"Nejra","family":"Bekta\u0161","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/040cm8d21","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larisa","family":"Be\u0161i\u0107","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/040cm8d21","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aida","family":"Kulo \u0106esi\u0107","sequence":"additional","affiliation":[{"name":"University of Sarajevo","place":["Sarajevo,Bosnia and Herzegovina"],"department":["Department of Pharmacology, Clinical Pharmacology and Toxicology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damir","family":"Marjanovi\u0107","sequence":"additional","affiliation":[{"name":"Institute for Anthropological Research","place":["Zagreb,Croatia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasminka","family":"Prguda-Muji\u0107","sequence":"additional","affiliation":[{"name":"4Health Institute Biomedical Diagnostics and Research Medicover Diagnostics","place":["Sarajevo,Bosnia and Herzegovina"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"49509","published-online":{"date-parts":[[2026,2,27]]},"container-title":["Medicinski Glasnik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medicinskiglasnik.ba\/article\/2599\/pdf\/download","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicinskiglasnik.ba\/article\/2599\/pdf\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:45:39Z","timestamp":1775468739000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicinskiglasnik.ba\/article\/id\/598\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,27]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,27]]},"published-print":{"date-parts":[[2026,2,27]]}},"URL":"https:\/\/doi.org\/10.17392\/1974-23-01","archive":["Internet Archive"],"relation":{},"ISSN":["1840-2445","1840-0132"],"issn-type":[{"value":"1840-2445","type":"electronic"},{"value":"1840-0132","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,27]]}}}