{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:48:39Z","timestamp":1785412119328,"version":"3.56.0"},"reference-count":0,"publisher":"Medical Association of Zenica-Doboj","issue":"1","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Medicinski Glasnik"],"published-print":{"date-parts":[[2026,2,27]]},"abstract":"<jats:p>&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;&amp;amp;nbsp;&amp;lt;\/strong&amp;gt;&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;Abstract&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;&amp;amp;nbsp;&amp;lt;\/strong&amp;gt;&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;Background: Optimal myocardial protection remains challenging in emergency coronary revascularization, especially in patients with severely reduced left ventricular function. Contemporary cardioplegia strategies aim to limit ischemia&amp;amp;ndash;reperfusion injury and enhance postoperative ventricular recovery. The aim of this study was to compare operative parameters, early postoperative outcomes, and myocardial functional recovery between single-dose Del Nido cardioplegia and conventional blood cardioplegia in adults with left ventricular ejection fraction (LVEF) &amp;amp;le;40% undergoing emergency isolated coronary artery bypass grafting (CABG).&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;Methods: This retrospective study included 150 consecutive patients with left ventricular ejection fraction (LVEF) &amp;amp;le;40% who underwent emergency isolated CABG between 2022 and 2024. Patients were assigned to either the Del Nido group (n=80) or the conventional blood cardioplegia group (n=70). Demographics, operative variables, postoperative complications, ventricular function changes, and short-term mortality were analyzed. Myocardial recovery was assessed using &amp;amp;Delta;EF (postoperative minus preoperative LVEF).&amp;amp;nbsp; .&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;Results: The Del Nido group demonstrated significantly shorter aortic cross-clamp and cardiopulmonary bypass times and required less intraoperative defibrillation. The incidence of postoperative atrial fibrillation was lower in the Del Nido group (18%) compared with conventional blood cardioplegia (29%). Improvement in ventricular function was greater with Del Nido (&amp;amp;Delta;EF +5.8&amp;amp;plusmn;2.1%) than with blood cardioplegia (+3.2&amp;amp;plusmn;2.4%). Rates of stroke, perioperative myocardial infarction, and early mortality were comparable between groups.&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;Conclusion: Single-dose Del Nido cardioplegia provides effective and safe myocardial protection in emergency low-EF CABG, offering improved operative efficiency and superior early ventricular recovery without increasing perioperative complications.&amp;lt;\/p&amp;gt;\n&amp;lt;p&amp;gt;&amp;lt;strong&amp;gt;&amp;amp;nbsp;&amp;lt;\/strong&amp;gt;&amp;lt;\/p&amp;gt;<\/jats:p>","DOI":"10.17392\/2110-23-01","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T07:20:27Z","timestamp":1772176827000},"page":"36-40","source":"Crossref","is-referenced-by-count":0,"title":["Enhanced myocardial protection in failing hearts:  comparative outcomes of single-dose Del Nido and  conventional blood cardioplegia in emergency low-ejection  fraction coronary artery bypass grafting (CABG)"],"prefix":"10.17392","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9814-7056","authenticated-orcid":false,"given":"emced","family":"Khalil","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/04mmwq306","id-type":"ROR","asserted-by":"publisher"}]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"49509","published-online":{"date-parts":[[2026,2,27]]},"container-title":["Medicinski Glasnik"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/medicinskiglasnik.ba\/article\/2711\/pdf\/download","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/medicinskiglasnik.ba\/article\/2711\/pdf\/download","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T09:45:37Z","timestamp":1775468737000},"score":1,"resource":{"primary":{"URL":"https:\/\/medicinskiglasnik.ba\/article\/id\/552\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,27]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,27]]},"published-print":{"date-parts":[[2026,2,27]]}},"URL":"https:\/\/doi.org\/10.17392\/2110-23-01","archive":["Internet Archive"],"relation":{},"ISSN":["1840-2445","1840-0132"],"issn-type":[{"value":"1840-2445","type":"electronic"},{"value":"1840-0132","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,27]]}}}