{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T06:06:32Z","timestamp":1783922792910,"version":"3.55.0"},"reference-count":0,"publisher":"Armed Forces Medical Services","issue":"1","license":[{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neurosciences"],"abstract":"<jats:p>Objectives: To define prognostic factors that affect clinical outcome of patients after surgical resection of spinal intramedullary ependymoma.\nMethods: A retrospective multi-center study, including all cases operated on from 2007 through 2024 at 3 institutes. Data on surgical factors included: resection extent, intraoperative neurophysiology monitoring methods, and intraoperative\/postoperative complications.\nResults: A total of 19 patients were included with a mean age of 37.8 years (SD = 13.2, range 8\u201357 years). The majority of ependymomas (n = 14, 73.7%) were in the cervical region. The most common presenting symptoms included pain in 14 patients (73.7%), sensory deficits in 11 patients (57.8%), and motor deficits 10 patients (52.6%). As per preoperative McCormick grading, 31.6%, 10.5%, and 31.6% were grade I, II, and III, respectively. Postoperatively, 57.9% of patients improved to McCormick grade I. Total gross tumor resection was achieved in 15 participants (78.9%). Syndromes, specifically neurofibromatosis type II, were significantly associated with a chance of recurrence (p = 0.004) and the need for a second surgery (p = 0.018).\nConclusion: The preoperative neurological status correlates significantly with the postoperative outcome of the patient.<\/jats:p>","DOI":"10.17712\/1658-3183.1004","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T17:06:37Z","timestamp":1776791197000},"page":"34-40","source":"Crossref","is-referenced-by-count":0,"title":["Predictors of Long-Term Outcome and Recurrence of Intramedullary Spinal Ependymomas: A multicenter study"],"prefix":"10.17712","volume":"31","author":[{"given":"Reem","family":"Albuhairan","sequence":"first","affiliation":[{"name":"Department of Pathology, Ministry of National Guard - Health Affairs, Riyadh, Kingdom of Saudi Arabia AND King Abdullah International Medical Research Center, Ministry of National Guard, Riyadh, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila","family":"Alqahtani","sequence":"additional","affiliation":[{"name":"King Abdullah International Medical Research Center, Ministry of National Guard, Riyadh, Kingdom of Saudi Arabia AND Department of Neurology, King Fahad Medical City, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Gamal","family":"Sayed","sequence":"additional","affiliation":[{"name":"Department of Neurology\/Internal Medicine, Security Forces Hospital, Makkah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Alkhaibary","sequence":"additional","affiliation":[{"name":"King Abdullah International Medical Research Center, Ministry of National Guard, Riyadh, Kingdom of Saudi Arabia AND Division of Neurosurgery, Department of Surgery, Ministry of National Guard - Health Affairs, Riyadh, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Khairy","sequence":"additional","affiliation":[{"name":"King Abdullah International Medical Research Center, Ministry of National Guard, Riyadh, Kingdom of Saudi Arabia AND Division of Neurosurgery, Department of Surgery, Ministry of National Guard - Health Affairs, Riyadh, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal","family":"Farash","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, King Faisal Specialist Hospital & Research Center, Riyadh, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali H.","family":"Alassiri","sequence":"additional","affiliation":[{"name":"Department of Pathology, Ministry of National Guard - Health Affairs, Riyadh, Kingdom of Saudi Arabia AND King Abdullah International Medical Research Center, Ministry of National Guard, Riyadh, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Alkhani","sequence":"additional","affiliation":[{"name":"King Abdullah International Medical Research Center, Ministry of National Guard, Riyadh, Kingdom of Saudi Arabia AND Division of Neurosurgery, Department of Surgery, Ministry of National Guard - Health Affairs, Riyadh, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56029","published-online":{"date-parts":[[2026,3,27]]},"container-title":["Neurosciences"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T05:24:22Z","timestamp":1783920262000},"score":1,"resource":{"primary":{"URL":"https:\/\/nsj.researchcommons.org\/journal\/vol31\/iss1\/5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,27]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,3,27]]}},"URL":"https:\/\/doi.org\/10.17712\/1658-3183.1004","relation":{},"ISSN":["1658-3183"],"issn-type":[{"value":"1658-3183","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,27]]}}}