{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T18:51:33Z","timestamp":1757616693198,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Fam Plann Reprod Health Care"],"accepted":{"date-parts":[[2001,9,12]]},"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To test the hypothesis that hospital referral for unexplained abdominal pain might occur less frequently in oral contraceptive (OC) users and more frequently in intrauterine device (IUD) users than in other women.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Design<\/jats:title>\n                  <jats:p>Prospective cohort study of 17 032 women using different methods of contraception [the Oxford-Family Planning Association (FPA) contraceptive study].<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Outcome measure<\/jats:title>\n                  <jats:p>Referral to hospital for unexplained abdominal pain (including pelvic pain) coded to ICD rubric 785.5 in the 8th Revision of the ICD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Referral was decreased by 13% (95% CI 0%-25%) in current or recent users of OCs in comparison with non-users, a difference that just reached statistical significance. No significant difference was found in the corresponding analysis for IUD users. Past users of OCs had much the same risk of referral as non-users, but the risk of referral in past users of an IUD was increased at all intervals examined, varying from 17% (95% CI -14%-55%) 13-24 months after discontinuation to 56% (95% CI 15%-107%) 73-96 months after discontinuation. Referral was 29% (95% CI 11%-50%) higher in smokers of 15 or more cigarettes a day than in non-smokers.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Referral to hospital for unexplained abdominal pain may be slightly reduced in current or recent OC users and moderately increased in past IUD users. The types of IUD used most commonly in the Oxford-FPA study are, however, no longer in current use today. Hospital referral for unexplained abdominal pain seems to be moderately increased in heavy cigarette smokers.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1783\/147118902101195802","type":"journal-article","created":{"date-parts":[[2005,3,5]],"date-time":"2005-03-05T01:30:57Z","timestamp":1109986257000},"page":"32-33","source":"Crossref","is-referenced-by-count":0,"title":["Contraception and unexplained abdominal pain"],"prefix":"10.1136","volume":"28","author":[{"given":"Martin","family":"Vessey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosemary","family":"Painter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2002,1,1]]},"reference":[{"key":"ref_1","first-page":"145","article-title":"Oral contraception and other factors in relation to hospital referral for menstrual problems without known underlying cause: findings in a large cohort study","volume":"22","author":"Vessey, M.; Painter, R.; Mant, J.","year":"1997","unstructured":"Vessey M, Painter R, Mant J. Oral contraception and other factors in relation to hospital referral for menstrual problems without known underlying cause: findings in a large cohort study. Br J Fam Plann 1997; 22: 145\u2013151.","journal-title":"Br J Fam Plann"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1136\/bmj.294.6586.1518","article-title":"Ovarian neoplasms, functional ovarian cysts and oral contraceptives","volume":"295","author":"Vessey, M.; Metcalfe, A.; Wells, C.","year":"1987","unstructured":"Vessey M, Metcalfe A, Wells C, et al. Ovarian neoplasms, functional ovarian cysts and oral contraceptives. 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The influence of method of contraception and cigarette smoking on menstrual patterns. Br J Obstet Gynaecol 1988; 95: 905\u2013910.","journal-title":"Br J Obstet Gynaecol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1017\/S0021932000010890","article-title":"A long-term follow-up study of women using different methods of contraception \u2013 an interim report","volume":"8","author":"Vessey, M.P.; Doll, R.; Peto, R.","year":"1976","unstructured":"Vessey MP, Doll R, Peto R, et al. A long-term follow-up study of women using different methods of contraception \u2013 an interim report. J Biosoc Sci 1976; 8: 373\u2013425.","journal-title":"J Biosoc Sci"},{"key":"ref_8","article-title":"The design and analysis of cohort studies","volume":"2","author":"Breslow, N.E.; Day, N.E.","year":"1987","unstructured":"Breslow NE, Day NE. Statistical methods in cancer research, vol. 2. The design and analysis of cohort studies. Lyon: IARC, 1987.","journal-title":"Statistical methods in cancer research"},{"key":"ref_9","first-page":"216","article-title":"Oral contraceptive use in relation to chest and limb symptoms","volume":"19","author":"Vessey, M.P.; Painter, R.","year":"1993","unstructured":"Vessey MP, Painter R. Oral contraceptive use in relation to chest and limb symptoms. Br J Fam Plann 1993; 19: 216\u2013217.","journal-title":"Br J Fam Plann"},{"key":"ref_10","article-title":"General Practitioners. Oral contraceptives and health","author":"of, Royal College","year":"1974","unstructured":"Royal College of General Practitioners. Oral contraceptives and health. London: Pitman Medical, 1974."},{"key":"ref_11","article-title":"The Walnut Creek contraceptive drug study. A prospective study of the side effects of oral contraceptives","volume":"81564","author":"Ramcharan, S.; Pellegrin, F.A.; Ray, R.","year":"1981","unstructured":"Ramcharan S, Pellegrin FA, Ray R, et al. The Walnut Creek contraceptive drug study. A prospective study of the side effects of oral contraceptives. Bethesda: NIH Publication No. 81564, 1981."}],"container-title":["Journal of Family Planning and Reproductive Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1783\/147118902101195802","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T20:06:22Z","timestamp":1757102782000},"score":1,"resource":{"primary":{"URL":"https:\/\/jfprhc.bmj.com\/lookup\/doi\/10.1783\/147118902101195802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,1]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2002,1,1]]},"published-print":{"date-parts":[[2002,1]]}},"alternative-id":["10.1783\/147118902101195802"],"URL":"https:\/\/doi.org\/10.1783\/147118902101195802","relation":{},"ISSN":["1471-1893","2045-2098"],"issn-type":[{"type":"print","value":"1471-1893"},{"type":"electronic","value":"2045-2098"}],"subject":[],"published":{"date-parts":[[2002,1]]}}}