{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T20:16:44Z","timestamp":1771013804446,"version":"3.50.1"},"reference-count":6,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Fam Plann Reprod Health Care"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:p>In the UK, mifepristone and gemeprost are licensed for medical termination of pregnancy (TOP) in the first trimester up to 63 days' amenorrhoea. Current practice, however, is to use low-dose (200 mg) mifepristone and misoprostol. We report a large cohort study using these drugs for medical TOP in the first trimester after 63 days amenorrhoea. Of 415 patients undergoing the procedure, 392 (95%) aborted completely and 96% required only two doses of misoprostol. We conclude that the regime is effective with few complications, however certain safeguards may be necessary for its widespread introduction<\/jats:p>","DOI":"10.1783\/147118903101197908","type":"journal-article","created":{"date-parts":[[2005,3,5]],"date-time":"2005-03-05T01:30:57Z","timestamp":1109986257000},"page":"243-244","source":"Crossref","is-referenced-by-count":2,"title":["Report from the Faculty of Family Planning and Reproductive Health Care AGM, May 2003: Medical termination of pregnancy in the late first trimester"],"prefix":"10.1136","volume":"29","author":[{"given":"P","family":"Stewart","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Fletcher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2003,10,1]]},"reference":[{"key":"ref_1","article-title":"Obstetricians and Gynaecologists (RCOG) Guideline No. 7. The care of women requesting induced abortion","author":"of, Royal College","year":"2000","unstructured":"Royal College of Obstetricians and Gynaecologists (RCOG) Guideline No. 7. The care of women requesting induced abortion. London: RCOG Press, 2000."},{"key":"ref_2","article-title":"Obstetricians and Gynaecologists (RCOG) Clinical Effectiveness Support Unit. National Audit of Induced Abortion 2000","author":"of, Royal College","year":"2001","unstructured":"Royal College of Obstetricians and Gynaecologists (RCOG) Clinical Effectiveness Support Unit. National Audit of Induced Abortion 2000. London: RCOG Press, 2001."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1111\/j.1471-0528.1990.tb02516.x","article-title":"The efficacy and tolerance of mifepristone and prostaglandin in first trimester termination of pregnancy","volume":"97","author":"Trial, U.K.Multicentre","year":"1990","unstructured":"UK Multicentre Trial. The efficacy and tolerance of mifepristone and prostaglandin in first trimester termination of pregnancy. Br J Obstet Gynaecol 1990; 97: 480\u2013486.","journal-title":"Br J Obstet Gynaecol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/j.1471-0528.2000.tb13273.x","article-title":"Task Force on Post-ovulatory Methods of Fertility Regulation. Comparison of two doses of mifepristone with misoprostol for early medical abortion: a randomised trial","volume":"107","author":"WHO","year":"2000","unstructured":"WHO Task Force on Post-ovulatory Methods of Fertility Regulation. Comparison of two doses of mifepristone with misoprostol for early medical abortion: a randomised trial. Br J Obstet Gynaecol 2000; 107: 524\u2013530.","journal-title":"Br J Obstet Gynaecol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1067\/mob.2003.267","article-title":"Medical abortion at 64 to 91 days of gestation: a review of 483 consecutive cases","volume":"188","author":"Hamoda, H.; Ashok, P.W.; Flett, G.M.M.","year":"2003","unstructured":"Hamoda H, Ashok PW, Flett GMM, et al. Medical abortion at 64 to 91 days of gestation: a review of 483 consecutive cases. Am J Obstet Gynecol 2003; 188: 1315\u20131319.","journal-title":"Am J Obstet Gynecol"},{"key":"ref_6","article-title":"Editor\u2019s Note A poster presentation on the above topic was awarded the Schering Health Care Award Poster Prize at the Faculty of Family Planning and Reproductive Health Care AGM in May 2003. The text of this poster presentation is to appear in print in another scientific journal in due course","unstructured":"Editor\u2019s Note A poster presentation on the above topic was awarded the Schering Health Care Award Poster Prize at the Faculty of Family Planning and Reproductive Health Care AGM in May 2003. The text of this poster presentation is to appear in print in another scientific journal in due course."}],"container-title":["Journal of Family Planning and Reproductive Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1783\/147118903101197908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T19:40:31Z","timestamp":1757101231000},"score":1,"resource":{"primary":{"URL":"https:\/\/jfprhc.bmj.com\/lookup\/doi\/10.1783\/147118903101197908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,10]]},"references-count":6,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2003,10,1]]},"published-print":{"date-parts":[[2003,10]]}},"alternative-id":["10.1783\/147118903101197908"],"URL":"https:\/\/doi.org\/10.1783\/147118903101197908","relation":{},"ISSN":["1471-1893","2045-2098"],"issn-type":[{"value":"1471-1893","type":"print"},{"value":"2045-2098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,10]]}}}