{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T00:16:30Z","timestamp":1768004190286,"version":"3.49.0"},"reference-count":12,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Fam Plann Reprod Health Care"],"accepted":{"date-parts":[[2005,5,6]]},"published-print":{"date-parts":[[2005,10]]},"abstract":"<jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Implanon\u00ae was introduced in the UK in September 1999. We present here the results of our first 106 Implanon insertions, performed over a period of 18 months. The aims of the study were to study the clinical and demographic profile of Implanon users, to assess the continuation rates of Implanon in the local population, and to identify the reasons for removal.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This was a case note-based study in which the data were transferred to a standardised pre-tested proforma.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The age range of the 106 Implanon users was 15\u201343 years. Eighty-six of these clients had their Implanon removed and the Implanon status of 20 clients is not known since they were lost to follow-up by our service. Of these 86 cases, 26 had completed the full 3-year period; therefore, the continuation rate at 3 years was 30.2%. The continuation rate at the end of 1 year was 69.8% and at 2 years was 44.1%. Of the 60 women who had their Implanon removed before the recommended 3-year period, the most common reason was for bleeding irregularity (24 cases, 40%).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This is the first published study set in the UK within a real-life setting to follow up a cohort of Implanon users for the full 3-year period. No contraceptive failures were found, replicating previous clinical trials. The continuation rate in this real-life situation was quite low compared to clinical trials. This is frequently the case when comparing real-life situations with clinical trials and may be in part due to higher motivation on the part of clinical trial participants.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1783\/147118905774480581","type":"journal-article","created":{"date-parts":[[2005,10,15]],"date-time":"2005-10-15T19:07:03Z","timestamp":1129403223000},"page":"310-312","source":"Crossref","is-referenced-by-count":28,"title":["An assessment of the first 3 years' use of Implanon\u00ae in Luton"],"prefix":"10.1136","volume":"31","author":[{"given":"Anjali","family":"Agrawal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2005,10,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1080\/13625180410001696223","article-title":"Experience with Implanon\u00ae in a northeast London family planning clinic","volume":"9","author":"Rai, K.; Gupta, S.; Cotter, S.","year":"2004","unstructured":"Rai K, Gupta S, Cotter S. Experience with Implanon\u00ae in a northeast London family planning clinic. Eur J Contracept Reprod Health Care 2004; 9: 39\u201346.","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0010-7824(93)90042-6","article-title":"Release characteristics, ovarian activity and menstrual bleeding pattern with a single contraceptive implant releasing 3ketodesogestrel","volume":"47","author":"Davies, G.C.; Feng, L.X.; Newton, JR, Van Beek; A, Coelingh-Bennink; H.J.","year":"1993","unstructured":"Davies GC, Feng LX, Newton JR, Van Beek A, Coelingh-Bennink HJ. Release characteristics, ovarian activity and menstrual bleeding pattern with a single contraceptive implant releasing 3ketodesogestrel. Contraception 1993; 47: 251\u2013261.","journal-title":"Contraception"},{"key":"ref_3","first-page":"3","article-title":"Implanon: a review of clinical studies","volume":"24","author":"Edwards, J.E.; Moore, A.","year":"1999","unstructured":"Edwards JE, Moore A. Implanon: a review of clinical studies. Br J Fam Plann 1999; 24: 3\u201316.","journal-title":"Br J Fam Plann"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1783\/147118902101196540","article-title":"An assessment of the use of Implanon in three community services","volume":"28","author":"Smith, A.; Reuter, S.","year":"2002","unstructured":"Smith A, Reuter S. An assessment of the use of Implanon in three community services. J Fam Plann Reprod Health Care 2002; 28: 193\u2013196.","journal-title":"J Fam Plann Reprod Health Care"},{"key":"ref_5","first-page":"332","article-title":"Long acting progestogen contraceptives","volume":"246","author":"Power, J.; Guillebaud, J.","year":"2002","unstructured":"Power J, Guillebaud J. Long acting progestogen contraceptives. Practitioner 2002; 246: 332\u2013333.","journal-title":"Practitioner"},{"issue":"91","key":"ref_6","first-page":"976","article-title":"The pharmacodynamics and efficacy of Implanon","volume":"58","author":"Croxatto, H.B.; Makarainan, L.","year":"1998","unstructured":"Croxatto HB, Makarainan L. The pharmacodynamics and efficacy of Implanon. Contraception 1998; 58: 91S\u201397S. 7 Croxatto HB, Urbancsek J, Massai R, Coelingh Bennink H, van Beek A. A multicentre efficacy and safety study of the single contraceptive implant Implanon. Hum Reprod 1999; 14: 976\u2013981.","journal-title":"Contraception; A multicentre efficacy and safety study of the single contraceptive implant Implanon"},{"issue":"99","key":"ref_7","first-page":"9","article-title":"An integrated of analysis of vaginal bleeding patterns in clinical trials of Implanon","volume":"58","author":"Affandi, B.","year":"1998","unstructured":"Affandi B. An integrated of analysis of vaginal bleeding patterns in clinical trials of Implanon. Contraception 1998; 58: 99S\u2013107S. 9 Agrawal A, Robinson C. Spontaneous snapping of an Implanon\u00ae in two halves in situ. J Fam Plann Reprod Health Care 2003; 29(4): 238.","journal-title":"Contraception; Spontaneous snapping of an Implanon\u00ae in two halves in situ"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1783\/147118902101196595","article-title":"Persistent vaginal bleeding in a patient with a broken Implanon\u00ae","volume":"28","author":"Pickard, S.; Bacon, L.","year":"2002","unstructured":"Pickard S, Bacon L. Persistent vaginal bleeding in a patient with a broken Implanon\u00ae. J Fam Plann Reprod Health Care 2002; 28: 207\u2013208.","journal-title":"J Fam Plann Reprod Health Care"},{"issue":"2","key":"ref_9","article-title":"Book Reviews Chromosome Abnormalities and Genetic Counseling. RJ McKinlay Gardner and GR Sutherland","volume":"514960","author":"0","year":"2004","unstructured":"Book Reviews Chromosome Abnormalities and Genetic Counseling. RJ McKinlay Gardner and GR Sutherland. New York, NY: Oxford University Press, 2004. ISBN: 0 19 514960 2. Price: \u00a349.50. Pages: 555 (hardback)"},{"key":"ref_10","article-title":"This is a weighty specialist text, now in its third edition. Since the first edition in 1989, the text has expanded vastly to take in repercussions of assisted reproduction and of the Human Genome Project. Nevertheless, this book retains a very human face, the writers consciously remembering the clients who continue to ask essentially the same questions about the impact of chromosomal abnormality on their families","unstructured":"This is a weighty specialist text, now in its third edition. Since the first edition in 1989, the text has expanded vastly to take in repercussions of assisted reproduction and of the Human Genome Project. Nevertheless, this book retains a very human face, the writers consciously remembering the clients who continue to ask essentially the same questions about the impact of chromosomal abnormality on their families."},{"key":"ref_11","first-page":"4","article-title":"Pediatric and Adolescent Gynecology: Evidence-based Practice. C Sultan (ed.)","volume":"7623","author":"3","year":"2004","unstructured":"Pediatric and Adolescent Gynecology: Evidence-based Practice. C Sultan (ed.). Basel, Switzerland: Karger, 2004. ISBN: 3 8055 7623 4. Price: \u00a3121.10. Pages: 269 (hardback)"},{"key":"ref_12","article-title":"The final chapters provide an overview of adolescent sexual health. A review from Finland highlights important aspects of sex and relationship education. Unfortunately, the chapter on contraception does not make any reference to the World Health Organization Medical Eligibility Criteria for Contraceptive Use (WHOMEC) and shows some discrepancies to guidelines developed by the Clinical Effectiveness Unit of the Faculty of Family Planning and Reproductive Health Care. The dosages and regimes of antibiotics mentioned in the chapter on sexual transmitted disease differ slightly from the recommendations made by the Royal College of Obstetricians and Gynaecologists. The guidance on cervical screening and the management of PAP smear abnormalities in adolescents differs from","unstructured":"The final chapters provide an overview of adolescent sexual health. A review from Finland highlights important aspects of sex and relationship education. Unfortunately, the chapter on contraception does not make any reference to the World Health Organization Medical Eligibility Criteria for Contraceptive Use (WHOMEC) and shows some discrepancies to guidelines developed by the Clinical Effectiveness Unit of the Faculty of Family Planning and Reproductive Health Care. The dosages and regimes of antibiotics mentioned in the chapter on sexual transmitted disease differ slightly from the recommendations made by the Royal College of Obstetricians and Gynaecologists. The guidance on cervical screening and the management of PAP smear abnormalities in adolescents differs from that of the British Society of Colposcopy and Cervical Pathology."}],"container-title":["Journal of Family Planning and Reproductive Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1783\/147118905774480581","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T17:52:17Z","timestamp":1757094737000},"score":1,"resource":{"primary":{"URL":"https:\/\/jfprhc.bmj.com\/lookup\/doi\/10.1783\/147118905774480581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2005,10,1]]},"published-print":{"date-parts":[[2005,10]]}},"alternative-id":["10.1783\/147118905774480581"],"URL":"https:\/\/doi.org\/10.1783\/147118905774480581","relation":{},"ISSN":["1471-1893","2045-2098"],"issn-type":[{"value":"1471-1893","type":"print"},{"value":"2045-2098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}