{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:35:04Z","timestamp":1761514504049,"version":"3.37.3"},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>Fiebre amarilla (FA) y leptospirosis son zoonosis end\u00e9micas subdiagnosticadas de las regiones tropicales de \u00c1frica y\u00a0Sudam\u00e9rica. Ambas, pueden ser cl\u00ednicamente indistinguibles y presentarse como s\u00edndrome febril icterohemorr\u00e1gico\u00a0agudo. Reportamos el caso de un var\u00f3n de 20 a\u00f1os, procedente del departamento de Amazonas que se present\u00f3 con\u00a0nueve d\u00edas de enfermedad caracterizada por falla multiorg\u00e1nica (compromiso neurol\u00f3gico, renal, hep\u00e1tico, respiratorio,\u00a0y hematol\u00f3gico). Recibi\u00f3 tratamiento antibi\u00f3tico, soporte transfusional, dial\u00edtico, hemodin\u00e1mico, y ventilatorio; y a pesar\u00a0de la gravedad del cuadro cl\u00ednico, evolucion\u00f3 favorablemente. Se confirm\u00f3 FA por Rt-PCR y se obtuvo serolog\u00eda positiva\u00a0para leptospira por ELISA y microaglutinaci\u00f3n. Sin embargo, no se pudo demostrar, desde el punto de vista laboratorial,\u00a0coinfecci\u00f3n real por FA y leptospira. Este caso de FA severa con desenlace no fatal enfatiza la importancia del diagn\u00f3stico\u00a0sindr\u00f3mico adecuado, y un tratamiento de soporte precoz y agresivo que puede salvar la vida del paciente.<\/jats:p>","DOI":"10.17843\/rpmesp.2019.364.4347","type":"journal-article","created":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T08:47:06Z","timestamp":1577177226000},"page":"700-4","source":"Crossref","is-referenced-by-count":3,"title":["Fiebre amarilla selv\u00e1tica con serolog\u00eda positiva para leptospira en un varon joven peruano"],"prefix":"10.17843","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1814-5593","authenticated-orcid":false,"given":"Edinson Dante","family":"Meregildo-Rodriguez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Villegas-Chiroque","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7920","published-online":{"date-parts":[[2019,12,6]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/4347\/3418","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/4347\/3418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T08:47:14Z","timestamp":1577177234000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/view\/4347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,6]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2019,12,6]]}},"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2019.364.4347","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"type":"electronic","value":"1726-4642"},{"type":"print","value":"1726-4634"}],"subject":[],"published":{"date-parts":[[2019,12,6]]}}}