{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T05:02:14Z","timestamp":1764046934782},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>Objetivo: Desarrollar un modelo de predicci\u00f3n de riesgo para infecci\u00f3n posoperatoria mayor (IPM) a cirug\u00eda cardiaca pedi\u00e1trica y validar el de la Society of Thoracic Surgeons (STS). Materiales y m\u00e9todos: Se analiz\u00f3 una cohorte retrospectiva de 1025 ni\u00f1os sometidos a cirug\u00eda cardiaca con circulaci\u00f3n extracorp\u00f3rea (CEC) del 2000 al 2010. Se emple\u00f3 un modelo de regresi\u00f3n log\u00edstica y se valid\u00f3 el modelo. Resultados: De los 1025 pacientes, 59 (5,8%) tuvieron al menos un episodio de IPM (4,8% sepsis, 1% mediastinitis, 0% endocarditis). La mortalidad hospitalaria (63% vs. 13%; p  0,001), al igual que la duraci\u00f3n de la ventilaci\u00f3n posoperatoria (301,6 vs. 34,3 horas; p  0,001) y la estancia en la unidad de cuidados intensivos (20,9 vs. 5,1 d\u00edas; p  0,001) fueron mayores en los pacientes con IPM. Los factores predictores fueron: edad, sexo, peso, cardiopat\u00eda cian\u00f3tica, RACHS-1 3-4, clase funcional IV modificada por Ross, estancia hospitalaria previa y antecedente de ventilaci\u00f3n mec\u00e1nica. El modelo tuvo un c-estad\u00edstico de 0,80 (intervalo de confianza [IC] al 95%: 0,74-0,86) y es cl\u00ednicamente \u00fatil. El modelo de la STS mostr\u00f3 un c-estad\u00edstico de 0,78 (IC 95%: 0,71-0,84) y Hosmer-Lemeshow de 18,2 (p = 0,020). Se realiz\u00f3 una comparaci\u00f3n entre ambos modelos empleando una prueba exacta de Fisher. Conclusi\u00f3n: Se desarroll\u00f3 un modelo para identificar preoperatoriamente a ni\u00f1os con alto riesgo de infecci\u00f3n grave despu\u00e9s de una cirug\u00eda cardiaca con CEC con buen desempe\u00f1o y calibraci\u00f3n. Asimismo, se valid\u00f3 el modelo de la STS con moderada discriminaci\u00f3n.<\/jats:p>","DOI":"10.17843\/rpmesp.2020.374.5064","type":"journal-article","created":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T20:51:26Z","timestamp":1609793486000},"page":"672-80","source":"Crossref","is-referenced-by-count":2,"title":["Desarrollo de un modelo de predicci\u00f3n de infecci\u00f3n mayor posterior a cirug\u00eda cardiaca pedi\u00e1trica"],"prefix":"10.17843","volume":"37","author":[{"given":"Alfredo M.","family":"Jauregui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula V.","family":"Urrunaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan A.","family":"Gonzales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis E.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinay","family":"Pasupuleti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewout W.","family":"Steyerberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian V.","family":"Hernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo W.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7920","published-online":{"date-parts":[[2020,11,30]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/5064\/3832","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/5064\/3833","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/5064\/3833","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T20:51:32Z","timestamp":1609793492000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/view\/5064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,30]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2020,8,21]]}},"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2020.374.5064","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"value":"1726-4642","type":"electronic"},{"value":"1726-4634","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11,30]]}}}