{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T18:07:32Z","timestamp":1740161252732,"version":"3.37.3"},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>El objetivo del estudio fue describir las caracter\u00edsticas cl\u00ednicas, la respuesta al tratamiento y posibles factores asociados de los pacientes con s\u00edndrome de Guillain Barr\u00e9 en el Instituto Nacional de Ciencias Neurol\u00f3gicas. Se realiz\u00f3 un estudio descriptivo sobre egresos hospitalarios durante el periodo 2017\u20132019. La respuesta al tratamiento se evalu\u00f3 mediante la escala de discapacidad de Hughes. De los 31 pacientes el 61,3% eran varones, y la edad promedio fue de 50 a\u00f1os. Al ingreso, el 87,1% de pacientes se encontraban en el grado 3 o 4 de la escala de Hughes, la mayor\u00eda con compromiso axonal, el cual estuvo asociado a discapacidad. Solo 22 pacientes recibieron recambio plasm\u00e1tico; luego de seis meses el 90,9% disminuy\u00f3 al menos en un grado en la escala de Hughes y el 42,8% quedaron sin discapacidad. En conclusi\u00f3n, se encontr\u00f3 un predominio del sexo masculino y del compromiso axonal, este \u00faltimo asociado a discapacidad<\/jats:p>","DOI":"10.17843\/rpmesp.2021.381.6233","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T21:07:34Z","timestamp":1620767254000},"page":"89-94","source":"Crossref","is-referenced-by-count":1,"title":["Caracter\u00edsticas cl\u00ednicas y respuesta al recambio plasm\u00e1tico terap\u00e9utico en los pacientes con s\u00edndrome de Guillain Barr\u00e9"],"prefix":"10.17843","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1106-5024","authenticated-orcid":false,"given":"Erik","family":"Guevara-Silva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0313-3987","authenticated-orcid":false,"given":"Sheila","family":"Castro-Suarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6896-3052","authenticated-orcid":false,"given":"C\u00e9sar","family":"Capar\u00f3-Zamalloa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8957-059X","authenticated-orcid":false,"given":"Jaqueline","family":"Cortez-Escalante","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4166-6944","authenticated-orcid":false,"given":"Mar\u00eda","family":"Meza-Vega","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7920","published-online":{"date-parts":[[2021,3,26]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/6233\/3954","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/6233\/4154","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/6233\/4154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T21:08:06Z","timestamp":1620767286000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/view\/6233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,26]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,3,26]]}},"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2021.381.6233","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"type":"electronic","value":"1726-4642"},{"type":"print","value":"1726-4634"}],"subject":[],"published":{"date-parts":[[2021,3,26]]}}}