{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:22:00Z","timestamp":1790882520090,"version":"4.1.0"},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>Con el objetivo de determinar la presencia de enterobacterias productoras de betalactamasas (bla) en muestras de efluentes hospitalarios, se realiz\u00f3 un estudio en dos hospitales de nivel II y III de Lima, Per\u00fa. Se identific\u00f3 y caracteriz\u00f3 el perfil de resistencia de las bacterias aisladas mediante el sistema MicroScan para 18 antimicrobianos, y mediante PCR convencional se determin\u00f3 la presencia de los genes de resistencia a betalactamasas de espectro de extendido (BLEE) (blaCTX-M, blaSHV, blaTEM, blaPER) y carbapenemasas (blaKPC, blaNDM, blaVIM, blaIMP). Se identific\u00f3 32 aislados (20 enterobacterias y 12 bacterias gramnegativas). Todas las bacterias aisladas presentaron multirresistencia. Se hall\u00f3 la presencia de genes BLEE (blaTEM) y carbapenemasas (blaKPC e blaIMP) en los hospitales evaluados. La liberaci\u00f3n de estos microorganismos a la v\u00eda p\u00fablica y la falta de tratamiento de los efluentes hospitalarios podr\u00eda ser un importante problema de salud p\u00fablica.<\/jats:p>","DOI":"10.17843\/rpmesp.2021.382.6202","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T17:06:35Z","timestamp":1628010395000},"page":"302-7","source":"Crossref","is-referenced-by-count":7,"title":["Efluentes hospitalarios como reservorio de enterobacterias productoras de betalactamasas y carbapenemasas"],"prefix":"10.17843","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3690-0014","authenticated-orcid":false,"given":"David R.","family":"Soriano-Moreno","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8909-1724","authenticated-orcid":false,"given":"Jos\u00e9","family":"Yareta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8652-8564","authenticated-orcid":false,"given":"Ana F.","family":"Rojas-Cosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8162-1321","authenticated-orcid":false,"given":"Alexander","family":"Fajardo-Loyola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6482-6093","authenticated-orcid":false,"given":"Diana","family":"Le\u00f3n-Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6183-3028","authenticated-orcid":false,"given":"Isabel","family":"Castillo-Quezada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7256-9122","authenticated-orcid":false,"given":"Mario","family":"Laura-Bejarano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2967-5998","authenticated-orcid":false,"given":"Milagros","family":"Hilario-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6547-2354","authenticated-orcid":false,"given":"Marco","family":"Galarza-P\u00e9rez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7741-0337","authenticated-orcid":false,"given":"Pool","family":"Marcos-Carbajal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7920","published-online":{"date-parts":[[2021,4,14]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/rpmesp\/article\/viewFile\/6202\/4126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/rpmesp\/article\/viewFile\/6202\/4126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T17:06:41Z","timestamp":1628010401000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/rpmesp\/article\/view\/6202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,14]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,3,26]]}},"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2021.382.6202","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"value":"1726-4642","type":"electronic"},{"value":"1726-4634","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4,14]]}}}