{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T17:21:27Z","timestamp":1759339287440,"version":"3.40.5"},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>Se evalu\u00f3 la eficacia de dos formulaciones de oxfendazol (OFZ) contra cisticercosis producidas localmente, al 22,5% y 10% en comparaci\u00f3n con una formulaci\u00f3n comercial (Synanthic 9,06%) en 22 cerdos naturalmente infectados, que recibieron una dosis oral de 30 mg\/kg. Los cerdos fueron sacrificados a las ocho semanas postratamiento para evaluar quistes en en sus carcasas, y se determin\u00f3 la eficacia cisticida a trav\u00e9s de la proporci\u00f3n de quistes degenerados sobre el total. Solo se encontraron quistes degenerados en la musculatura, coraz\u00f3n y lengua de los cerdos tratados con OFZ en todos los grupos, lo cual muestra una eficacia del 100%. En los cerebros se encontraron quistes viables y degenerados, con una eficacia menor en todos los grupos (65% [OFZ comercial], 47% [OFZ local 22,5%] y 31% [OFZ local 10%], p = 0,355. Las formulaciones de OFZ producidas localmente fueron igual de efectivas que la formulaci\u00f3n comercial y pueden proporcionar una alternativa para el tratamiento de la cisticercosis porcina.<\/jats:p>","DOI":"10.17843\/rpmesp.2021.382.6539","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T17:06:35Z","timestamp":1628010395000},"page":"296-301","source":"Crossref","is-referenced-by-count":1,"title":["Eficacia de dos formulaciones de oxfendazol producidas localmente para el tratamiento de la cisticercosis en cerdos infectados naturalmente"],"prefix":"10.17843","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8743-5012","authenticated-orcid":false,"given":"Gianfranco","family":"Arroyo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5797-3052","authenticated-orcid":false,"given":"Javier A.","family":"Bustos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4464-3107","authenticated-orcid":false,"given":"Juan F.","family":"Calcina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9608-4875","authenticated-orcid":false,"given":"Linda","family":"Gallegos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8993-3223","authenticated-orcid":false,"given":"Ana","family":"Vargas-Calla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7909-979X","authenticated-orcid":false,"given":"Luis A.","family":"Gomez-Puerta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8389-4139","authenticated-orcid":false,"given":"Teresa","family":"Lopez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9037-0712","authenticated-orcid":false,"given":"Robert H.","family":"Gilman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4633-6269","authenticated-orcid":false,"given":"H\u00e9ctor H.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1909-1873","authenticated-orcid":false,"given":"Armando E.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grupo de Trabajo","family":"En Cisticercosis en Per\u00fa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7920","published-online":{"date-parts":[[2021,7,7]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/rpmesp\/article\/viewFile\/6539\/4318","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/rpmesp\/article\/viewFile\/6539\/4318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T17:06:48Z","timestamp":1628010408000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/rpmesp\/article\/view\/6539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,7]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,3,26]]}},"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2021.382.6539","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"type":"electronic","value":"1726-4642"},{"type":"print","value":"1726-4634"}],"subject":[],"published":{"date-parts":[[2021,7,7]]}}}