{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T18:07:07Z","timestamp":1740161227153,"version":"3.37.3"},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>La nocardiosis cerebral es una entidad rara que ha sido reportada principalmente en inmunosuprimidos, y en la actualidad no se dispone de gu\u00edas cl\u00ednicas que recomienden un tratamiento de primera l\u00ednea. Presentamos el caso de un adulto mayor, inmunocompetente, con cuadro de encefalopat\u00eda y hemiparesia izquierda, asociado a lesiones compatibles con absceso cerebral m\u00faltiple y sugerente de etiolog\u00eda infecciosa. Recibi\u00f3, inicialmente, tratamiento para la tuberculosis, absceso bacteriano y toxoplasmosis, sin respuesta cl\u00ednica favorable. Se inici\u00f3 un tratamiento emp\u00edrico para la nocardiosis con meropenem y trimetoprim\/sulfametoxazol, y se logr\u00f3 mejor\u00eda cl\u00ednica e imagenol\u00f3gica. La ocurrencia de eventos adversos obliga el uso temporal de medicamentos alternativos. Se resaltan algunos criterios a considerar para incluir la nocardiosis en el diagn\u00f3stico diferencial en los casos de absceso cerebral m\u00faltiple y se mencionan los m\u00e9todos diagn\u00f3sticos de laboratorio y los f\u00e1rmacos para iniciar un tratamiento emp\u00edrico.<\/jats:p>","DOI":"10.17843\/rpmesp.2021.383.7330","type":"journal-article","created":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T17:24:46Z","timestamp":1635269086000},"page":"463-6","source":"Crossref","is-referenced-by-count":0,"title":["Absceso cerebral por Nocardia sp. en un paciente inmunocompetente en el Per\u00fa: reporte de caso"],"prefix":"10.17843","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9394-1971","authenticated-orcid":false,"given":"Pamela","family":"Huaman\u00ed-Charagua","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6172-3400","authenticated-orcid":false,"given":"Jes\u00fas","family":"Portocarrero-Nieto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8396-6227","authenticated-orcid":false,"given":"Gian Marco","family":"Arango-Rojas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2027-1890","authenticated-orcid":false,"given":"Alan","family":"Latorre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9097-0638","authenticated-orcid":false,"given":"Stalin","family":"Vilcarromero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7920","published-online":{"date-parts":[[2021,9,15]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/7330\/4376","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/7330\/4376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T17:25:06Z","timestamp":1635269106000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/view\/7330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,15]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,8,11]]}},"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2021.383.7330","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"type":"electronic","value":"1726-4642"},{"type":"print","value":"1726-4634"}],"subject":[],"published":{"date-parts":[[2021,9,15]]}}}