{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:47:48Z","timestamp":1790898468888,"version":"4.1.0"},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>El objetivo del estudio fue identificar molecularmente los genes de virulencia y resistencia a macr\u00f3lidos en aislamientos cl\u00ednicos de Streptococcus agalactiae (EGB), recuperados en 2019 a partir de secreci\u00f3n vaginal (n=9) y orina (n=22), en dos establecimientos de salud de Lima. La identificaci\u00f3n y susceptibilidad antimicrobiana se determinaron por el sistema automatizado Vitek\u00ae 2, se confirm\u00f3 la identificaci\u00f3n fenot\u00edpicamente; la resistencia a macr\u00f3lidos por el m\u00e9todo D-test; la identificaci\u00f3n de genes de virulencia (lmb, bca y rib) y de resistencia a macr\u00f3lidos (ermB, ermTR y mefA) por reacci\u00f3n en cadena de la polimerasa (PCR). El fenotipo y genotipo de resistencia a macr\u00f3lidos predominante fue cMLSb (12\/31) y ermB (11\/31), y el gen de virulencia m\u00e1s frecuente fue lmb (23\/31). Todos fueron sensibles a penicilina, ampicilina y vancomicina. Estos hallazgos muestran la necesidad de implementar estudios de epidemiolog\u00eda molecular que permitan un adecuado conocimiento y seguimiento de EGB en el Per\u00fa.<\/jats:p>","DOI":"10.17843\/rpmesp.2021.384.8726","type":"journal-article","created":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T17:40:11Z","timestamp":1642527611000},"page":"615-20","source":"Crossref","is-referenced-by-count":5,"title":["Caracterizaci\u00f3n molecular de genes de virulencia (lmb, bca y rib) y de resistencia a macr\u00f3lidos (ermB, ermTR y mefA) en aislamientos cl\u00ednicos de Streptococcus agalactiae"],"prefix":"10.17843","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7619-4353","authenticated-orcid":false,"given":"Angie","family":"Pulido-Colina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9534-5746","authenticated-orcid":false,"given":"Javier","family":"Soto Pastrana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4059-9842","authenticated-orcid":false,"given":"Ester","family":"Valencia-Bazalar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2743-9035","authenticated-orcid":false,"given":"Milagros","family":"Zavaleta Apestegui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7920","published-online":{"date-parts":[[2021,12,14]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/8726\/4583","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/viewFile\/8726\/4583","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T17:40:22Z","timestamp":1642527622000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/view\/8726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,14]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,12,13]]}},"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2021.384.8726","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"value":"1726-4642","type":"electronic"},{"value":"1726-4634","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12,14]]}}}