{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T08:14:29Z","timestamp":1768810469992,"version":"3.49.0"},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","license":[{"start":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T00:00:00Z","timestamp":1671408000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>El prop\u00f3sito del presente estudio fue describir las caracter\u00edsticas cl\u00ednicas, serotipos y susceptibilidad antibi\u00f3tica en pacientes con enfermedad neumoc\u00f3cica invasiva (ENI). Se revisaron las historias cl\u00ednicas de los pacientes con ENI hospitalizados en el Instituto Nacional de Salud del Ni\u00f1o-Bre\u00f1a (Lima, Per\u00fa). Se evaluaron a 29 pacientes. La mediana de edad fue 1,9 a\u00f1os (rango intercuart\u00edlico 1 a 4 a\u00f1os). El 51,7% eran mujeres y la forma cl\u00ednica de la ENI m\u00e1s frecuente fue la bacteriemia en 18 (62,1%) pacientes. El 65,5% ten\u00eda el esquema de vacunaci\u00f3n completo, seg\u00fan el Ministerio de Salud de Per\u00fa. El 82,8% del aislamiento del germen fue de sangre. La resistencia antibi\u00f3tica fue m\u00e1s frecuente a la eritromicina (55,2%), trimetoprim-sulfametoxazol (48,3%) y penicilina (24,1%). Los serotipos registrados fueron 6C, 19A, 23A y 24F. Un paciente falleci\u00f3 por meningitis. En conclusi\u00f3n, la ENI fue m\u00e1s frecuente en ni\u00f1osde uno a cinco a\u00f1os y en la forma cl\u00ednica de bacteriemia. Se encontraron cinco serotipos reportados en estudios previos con resistencia a penicilina y eritromicina.<\/jats:p>","DOI":"10.17843\/rpmesp.2022.394.12054","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T13:55:15Z","timestamp":1673272515000},"page":"469-73","source":"Crossref","is-referenced-by-count":2,"title":["Enfermedad neumoc\u00f3cica invasiva en pacientes de un hospital pedi\u00e1trico de Per\u00fa, 2017-2020"],"prefix":"10.17843","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3711-0751","authenticated-orcid":false,"given":"Julio Guillermo","family":"Mar\u00edn-Portocarrero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7576-4609","authenticated-orcid":false,"given":"Alan","family":"Quispe-Sanchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1968-5893","authenticated-orcid":false,"given":"Flor de Maria","family":"Charca-Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8283-6669","authenticated-orcid":false,"given":"No\u00e9","family":"Atamari-Anahui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7920","published-online":{"date-parts":[[2022,12,19]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/download\/12054\/5163","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/download\/12054\/5163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T13:55:37Z","timestamp":1673272537000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/view\/12054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,19]]},"references-count":0,"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2022.394.12054","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"value":"1726-4642","type":"electronic"},{"value":"1726-4634","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12,19]]}}}