{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T21:51:46Z","timestamp":1793829106403,"version":"4.6.1"},"reference-count":0,"publisher":"Instituto Nacional de Salud (Peru)","license":[{"start":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T00:00:00Z","timestamp":1718928000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Peru Med Exp Salud Publica"],"abstract":"<jats:p>Objetivos. Evaluar la presencia y sensibilidad a los antimicrobianos de cepas de Escherichia coli aisladas de 24 muestras de agua de riego del r\u00edo R\u00edmac de Lima Este, Per\u00fa. Materiales y m\u00e9todos. Las cepas de E. coli fueron identificadas por PCR. La susceptibilidad a los\u00a0 antibi\u00f3ticos se procesaron por el m\u00e9todo de difusi\u00f3n en disco. Los genes implicados en betalactamasas de espectro extendido (BLEE), quinolonas y virulencia se determinaron por PCR. Resultados. Todas las muestras superaron los l\u00edmites permisibles establecidos en las Normas de Calidad Ambiental para el riego de hortalizas. De los 94 aisaldos, el 72,3% mostr\u00f3 resistencia al menos a un antibi\u00f3tico, el 24,5% eran\u00a0 multirresistentes (MDR) y el 2,1% extremadamente\u00a0 resistentes. Los mayores porcentajes de resistencia se observaron para ampicilina-sulbactam (57,1%), el \u00e1cido nalid\u00edxico (50%), trimetoprim-sulfametoxazol (35,5%) y ciprofloxacino (20,4%). Entre los aislados, el 3,2% presentaba fenotipo BLEE relacionado con el gen bla CTX-M-15. Los mecanismos transferibles de resistencia a las quinolonas, qnrB fueron m\u00e1s frecuentes (20,4%), y el 2,04% ten\u00edan el qnrS. Se calcularon que el 5,3% eran E. coli diarreag\u00e9nicas y de estas, el 60% eran E. coli enterotoxig\u00e9nicas, el 20% E. coli enteropat\u00f3genas y el 20% E. coli enteroagregantes. Conclusiones. Los resultados muestran la existencia de patotipos\u00a0 diarreog\u00e9nicos en el agua utilizada para el riego de productos frescos y destaca la presencia de E. coli productores de BLEE y MDR, demostrando el papel que juega el agua de riego en la diseminaci\u00f3n de genes de resistencia en el Per\u00fa.<\/jats:p>","DOI":"10.17843\/rpmesp.2024.412.13246","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T19:52:33Z","timestamp":1718999553000},"page":"114-20","source":"Crossref","is-referenced-by-count":3,"title":["Resistance to cephalosporins and quinolones by &lt;i&gt;Escherichia coli&lt;\/i&gt; isolated from irrigation water from eastern Lima, Per\u00fa","Resistencia a cefalosporinas y quinolonas en &lt;i&gt;Escherichia coli&lt;\/i&gt;\u00a0 aisladas de agua de riego en r\u00edo R\u00edmac de Lima Este, Per\u00fa"],"prefix":"10.17843","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7369-2325","authenticated-orcid":false,"given":"M\u00f3nica","family":"Huam\u00e1n Iturrizaga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6617-6402","authenticated-orcid":false,"given":"Gina","family":"Salvador-Luj\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1435-5593","authenticated-orcid":false,"given":"Liliana","family":"Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4304-1403","authenticated-orcid":false,"given":"Jeanne Alba","family":"Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7553-3268","authenticated-orcid":false,"given":"Lino","family":"Velasquez Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3996-8090","authenticated-orcid":false,"given":"Julio Daniel","family":"Pacheco Perez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8384-2315","authenticated-orcid":false,"given":"Maria J.","family":"Pons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7920","published-online":{"date-parts":[[2024,6,21]]},"container-title":["Revista Peruana de Medicina Experimental y Salud P\u00fablica"],"original-title":[],"link":[{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/download\/13246\/5623","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/download\/13246\/5623","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T19:52:41Z","timestamp":1718999561000},"score":1,"resource":{"primary":{"URL":"https:\/\/rpmesp.ins.gob.pe\/index.php\/rpmesp\/article\/view\/13246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,21]]},"references-count":0,"URL":"https:\/\/doi.org\/10.17843\/rpmesp.2024.412.13246","relation":{},"ISSN":["1726-4642","1726-4634"],"issn-type":[{"value":"1726-4642","type":"electronic"},{"value":"1726-4634","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6,21]]}}}