{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T04:16:11Z","timestamp":1768796171913,"version":"3.49.0"},"reference-count":0,"publisher":"Laeknabladid\/The Icelandic Medical Journal","issue":"01","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["LBL"],"published-print":{"date-parts":[[2024,1,5]]},"abstract":"<jats:p>INTRODUCTION: No recent studies exist on lower extremity amputations (LLAs) in Iceland. The aim of this study was to investigate LLA incidence in Iceland 2010-2019 and preceding procedures in amputations induced by peripheral arterial disease (PAD) and diabetes mellitus (DM). MATERIAL AND METHODS: Retrospective study on clinical records of all patients (&gt;18 years) who underwent LLA in Iceland\u2019s two main hospitals during 2010-2019. Patients were excluded if LLA was performed for reasons other than DM and\/or PAD. Symptoms, medication and circulation assessment were recorded from first hospital visit due to symptoms, and prior to the last LLA, respectively. Previous arterial surgeries and amputations were also recorded. RESULTS: A total of 167 patients underwent LLA. Thereof, 134 (77 \u00b1 11 years, 93 men and 41 woman) due to DM and\/or PAD. The LLA-rate due to those diseases increased from 4.1\/100,000 inhabitants in 2010-2013 to 6.7\/100,000 in 2016-2019 (p=0,04). Risk factors were mainly hypertension, 84%, and smoking, 69%. Chronic limb-threatening ischemia induced 71% of first hospital visits. Revascularisations were performed (66% endovascular) in 101 patients. Non-diabetic patients were 52% and had statins less frequently prescribed than DM patients (26:45, p&lt;0.001). CONCLUSION: DM and\/or PAD are the leading causes of LLA in Iceland. Amputation rate increased during the period but is low in an international context. Amputation is most often preceded by arterial surgery. DM is present in almost half of cases, similar or less than in most other countries. Opportunities for improved prevention should aim on earlier diagnosis and preventive treatment of non-diabetic individuals with PAD.<\/jats:p>","DOI":"10.17992\/lbl.2024.01.776","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T10:41:16Z","timestamp":1704192076000},"page":"20-27","source":"Crossref","is-referenced-by-count":1,"title":["Lower Limb Amputations in Patients with Peripheral Arterial Disease and\/or Diabetes in Iceland 2010-2019; revascularisation, comorbidities and risk factors"],"prefix":"10.17992","volume":"110","author":[{"name":"School of Health Sciences, University of Akureyri, Iceland, Vascular surgery Unit, Landsp\u00edtali University Hospital, Reykjav\u00edk, Iceland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f3lr\u00fan D\u00f6gg","family":"\u00c1rnad\u00f3ttir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gu\u00f0bj\u00f6rg","family":"P\u00e1lsd\u00f3ttir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Wound care Unit, Landsp\u00edtali University Hospital, Reykjav\u00edk, Iceland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Logason","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Vascular surgery Unit, Landsp\u00edtali University Hospital, Reykjav\u00edk, Iceland, Faculty of Medicine, University of Iceland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ragnhei\u00f0ur Harpa","family":"Arnard\u00f3ttir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"School of Health Sciences, University of Akureyri, Iceland, Rehabilitation Unit, Akureyri Hospital, Iceland, Department of Medical Sciences, Respiratory-, allergy- and sleep research, Uppsala University, Sweden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7439","published-online":{"date-parts":[[2024,1,5]]},"container-title":["L\u00e6knabla\u00f0i\u00f0"],"original-title":["Aflimanir ofan \u00f6kkla 2010-2019 vegna \u00fat\u00e6\u00f0asj\u00fakd\u00f3ms og\/e\u00f0a sykurs\u00fdki A\u00f0dragandi og \u00e1h\u00e6ttu\u00fe\u00e6ttir"],"deposited":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T10:41:19Z","timestamp":1704192079000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.laeknabladid.is\/tolublod\/2024\/01\/nr\/8514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,5]]},"references-count":0,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2024,1,5]]},"published-print":{"date-parts":[[2024,1,5]]}},"URL":"https:\/\/doi.org\/10.17992\/lbl.2024.01.776","relation":{},"ISSN":["0023-7213","1670-4959"],"issn-type":[{"value":"0023-7213","type":"print"},{"value":"1670-4959","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,5]]}}}