{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:40:36Z","timestamp":1747201236695,"version":"3.40.5"},"reference-count":0,"publisher":"Ideggyogyaszati Szemle Journal","issue":"3-4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>Kutat\u00e1sunk c\u00e9lja volt egy progn\u00f3zist j\u00f3sl\u00f3 \u00e9s ter\u00e1pi\u00e1s opci\u00f3t aj\u00e1nl\u00f3 pontrendszer l\u00e9trehoz\u00e1sa a gerincmetaszt\u00e1zissal \u00e9rintett betegek sz\u00e1m\u00e1ra. Az egyre b\u0151v\u00fcl\u0151 onkoter\u00e1pi\u00e1s lehet\u0151s\u00e9gek \u00e9s a prolong\u00e1lt t\u00fal\u00e9l\u00e9s miatt egyre gyakrabban foglalkozunk a primer tumor csont\u00e1tt\u00e9tei miatt kialakult klinikai t\u00fcnetek megold\u00e1s\u00e1val. A csigolya\u00e1tt\u00e9tek az okozott neurol\u00f3giai deficitt\u00fcnetek, illetve a f\u00e1jdalom \u00e1ltal szignifik\u00e1ns \u00e9letmin\u0151s\u00e9gbeni cs\u00f6kken\u00e9st okozhatnak, \u00e9s a v\u00e1rhat\u00f3 \u00e9lettartamot is jelent\u0151sen befoly\u00e1solhatj\u00e1k. A progn\u00f3zist megfelel\u0151 pontoss\u00e1ggal j\u00f3sl\u00f3 pontrendszer seg\u00edts\u00e9g\u00fcnkre lehet a szem\u00e9lyre szabott gy\u00f3gy\u00edt\u00e1s megval\u00f3s\u00edt\u00e1s\u00e1ban. Retrospekt\u00edv klinikai vizsg\u00e1latot v\u00e9gezt\u00fcnk az Orsz\u00e1gos Ment\u00e1lis, Ideggy\u00f3gy\u00e1szati \u00e9s Idegseb\u00e9szeti Int\u00e9zetben a 2008 \u00e9s 2018 k\u00f6z\u00f6tt m\u0171t\u00e9ti \u00faton kezelt 18 \u00e9v feletti gerinc\u00e1tt\u00e9tes betegek adataib\u00f3l. 454 beteg adatait elemezt\u00fck. T\u00fal\u00e9l\u00e9si anal\u00edzist (Kaplan\u2013Meier-, log-rank-, Cox-modell) v\u00e9gezt\u00fcnk, h\u00e1l\u00f3zati korrel\u00e1ci\u00f3s vizsg\u00e1lat seg\u00edts\u00e9g\u00e9vel v\u00e1lasztottuk ki pontrendszer\u00fcnk prognosztikai faktorait \u00fagy, hogy a v\u00e1g\u00f3pont-anal\u00edzis sor\u00e1n maxim\u00e1ljuk annak C \u00e9rt\u00e9k\u00e9t (predikci\u00f3s k\u00e9pess\u00e9gi index\u00e9t). Multivari\u00e1ns Cox-anal\u00edzis eredm\u00e9nyek\u00e9nt \u00f6t prognosztikai faktort azonos\u00edtottunk (a primer tumor t\u00edpusa, \u00e9letkor, j\u00e1r\u00f3k\u00e9pess\u00e9g, belszervi \u00e1tt\u00e9tek, sz\u00e9rumfeh\u00e9rjeszint). Rendszer\u00fcnk a 10 \u00e9ves vizsg\u00e1lt peri\u00f3dusban \u00e1tlagosan 70,6%-os pontoss\u00e1ggal prognosztiz\u00e1lt. Szimpt\u00f3m\u00e1s, m\u0171t\u00e9ten \u00e1tesett, gerinc\u00admetaszt\u00e1zisban szenved\u0151 betegek nagy esetsz\u00e1m\u00fa, egycentrumos, retrospekt\u00edv m\u0171t\u00e9ti adatait felhaszn\u00e1lva l\u00e9trehoztuk rizik\u00f3becsl\u0151 rendszer\u00fcnket, ami seg\u00edtheti a ter\u00e1pia megv\u00e1laszt\u00e1s\u00e1t. Rizik\u00f3kalkul\u00e1torunk online is el\u00e9rhet\u0151 az al\u00e1bbi c\u00edmen: https:\/\/emk.semmelweis.hu\/gerincmet.<\/jats:p>","DOI":"10.18071\/isz.75.0117","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T11:40:04Z","timestamp":1648554004000},"page":"117-127","source":"Crossref","is-referenced-by-count":0,"title":["\u00daj, innovat\u00edv progn\u00f3ziskalkul\u00e1tor \u00e1tt\u00e9tes gerinctumoros betegek sz\u00e1m\u00e1ra"],"prefix":"10.18071","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0848-1182","authenticated-orcid":false,"given":"Tam\u00e1s","family":"Mezei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e1nos","family":"B\u00e1skay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Pollner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Horv\u00e1th","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor","family":"Czigl\u00e9czki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Banczerowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7411","published-online":{"date-parts":[[2022]]},"container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"original-title":[],"deposited":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T12:18:29Z","timestamp":1648556309000},"score":1,"resource":{"primary":{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/new-innovative-prognosis-calculator-for-patients-with-metastatic-spinal-tumors"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":0,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2022]]},"published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.18071\/isz.75.0117","relation":{},"ISSN":["0019-1442","2498-6208"],"issn-type":[{"type":"print","value":"0019-1442"},{"type":"electronic","value":"2498-6208"}],"subject":[],"published":{"date-parts":[[2022]]}}}