{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:40:42Z","timestamp":1747201242537,"version":"3.40.5"},"reference-count":0,"publisher":"Ideggyogyaszati Szemle Journal","issue":"11-12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>Background and purpose \u2013 Although serum anti-neuronal antibodies are found in acute ischemic stroke (AIS) patients, it is not completely clear whether they are already present before the cerebrovascular event or emerge thereafter. Methods \u2013 Sera of 21 consecutive firstever AIS patients were collected within the first day of AIS (baseline), as well as 1 and 6 months after AIS. Well-characterized and novel anti-neuronal antibodies were investigated by cell-based assays, immunoblotting and indirect immunohistochemistry. Results \u2013 None of the AIS sera collected at different time points showed well-characterized antibodies. In 7 patients, 1- and 6-month sera (but not baseline sera) showed IgG mostly reacting with soma and dendrites of cerebellar Purkinje cells. Antibody-positive patients did not differ in terms of clinical and etiological features. Conclusion \u2013 Our results provide evidence for the antibody-triggering action of AIS. Although anti-cerebellar antibodies are not associated with the severity of stroke, they may potentially contribute to chronic poststroke complications and disability.<\/jats:p>","DOI":"10.18071\/isz.76.0394","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T12:39:39Z","timestamp":1701779979000},"page":"394-398","source":"Crossref","is-referenced-by-count":0,"title":["Cerebellar antibodies in post-stroke sera of acute ischemic stroke patients"],"prefix":"10.18071","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2048-4930","authenticated-orcid":false,"given":"Murat Mert","family":"Atmaca","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0545-4699","authenticated-orcid":false,"given":"Ece","family":"Erda\u011f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4395-5141","authenticated-orcid":false,"given":"Serkan","family":"Demir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9027-5291","authenticated-orcid":false,"given":"Hande","family":"Y\u00fcceer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8727-1003","authenticated-orcid":false,"given":"Melek \u00c7olak","family":"Atmaca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9851-8577","authenticated-orcid":false,"given":"Cem \u0130smail","family":"K\u00fc\u00e7\u00fckali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3286-2652","authenticated-orcid":false,"given":"Murat","family":"K\u00fcrt\u00fcnc\u00fc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4483-0394","authenticated-orcid":false,"given":"Erdem","family":"T\u00fcz\u00fcn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7411","published-online":{"date-parts":[[2023]]},"container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"original-title":[],"link":[{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/cerebellar-antibodies-in-post-stroke-sera-of-acute-ischemic-stroke-patients\/pdf-open","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T12:39:47Z","timestamp":1701779987000},"score":1,"resource":{"primary":{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/cerebellar-antibodies-in-post-stroke-sera-of-acute-ischemic-stroke-patients"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":0,"journal-issue":{"issue":"11-12","published-online":{"date-parts":[[2023]]},"published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.18071\/isz.76.0394","relation":{},"ISSN":["0019-1442","2498-6208"],"issn-type":[{"type":"print","value":"0019-1442"},{"type":"electronic","value":"2498-6208"}],"subject":[],"published":{"date-parts":[[2023]]}}}