{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T05:40:43Z","timestamp":1747201243561,"version":"3.40.5"},"reference-count":0,"publisher":"Ideggyogyaszati Szemle Journal","issue":"3-4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"published-print":{"date-parts":[[2024]]},"abstract":"<jats:p>H\u00e1tt\u00e9r \u00e9s c\u00e9l \u2013 Az arteria centralis retinae okkl\u00fazi\u00f3 (ACRO) eddigi konzervat\u00edv ter\u00e1pi\u00e1i limit\u00e1lt hat\u00e9konys\u00e1g\u00faak, szem\u00e9szeti oszt\u00e1lyokon t\u00f6rt\u00e9ntek, ahogyan az egys\u00e9ges protokoll n\u00e9lk\u00fcli etiol\u00f3giai vizsg\u00e1latok is. Pedig az ACRO a k\u00f6zponti idegrendszeri ischaemi\u00e1s stroke anal\u00f3gi\u00e1j\u00e1nak tekinthet\u0151, \u00edgy a sziszt\u00e9m\u00e1s thrombolysis \u00e9s a multidiszciplin\u00e1ris ell\u00e1t\u00e1s hasonl\u00f3an hat\u00e9kony lehet. Emiatt 2022 m\u00e1jusa \u00f3ta a Semmelweis Egyetemen klinikai vizsg\u00e1lat keret\u00e9ben a 4,5 \u00f3r\u00e1n bel\u00fcl diagnosztiz\u00e1lt ACRO thrombolysiskezel\u00e9s\u00e9t \u00e9s etiol\u00f3giai vizsg\u00e1latait v\u00e9gezz\u00fck egys\u00e9ges protokoll alapj\u00e1n. Vizsg\u00e1latunk c\u00e9lja a szem\u00e9szeti, nem protokoll szerinti, \u00e9s a multidiszciplin\u00e1ris, protokoll szerinti ACRO-ell\u00e1t\u00e1s \u00f6sszehasonl\u00edt\u00e1sa. M\u00f3dszerek \u2013 \u00c1ttekintett\u00fck a 2013 \u00e9s 2022 k\u00f6z\u00f6tt a Szem\u00e9szeti Klinik\u00e1n ACRO-val konzervat\u00edvan \u00e9s 6 \u00f3r\u00e1n bel\u00fcl paracentesissel is kezelt betegek l\u00e1t\u00e1s\u00e9less\u00e9g-v\u00e1ltoz\u00e1s\u00e1t, fellelhet\u0151 neurol\u00f3giai \u00e9s cardiovascularis vizsg\u00e1latainak eredm\u00e9nyeit, valamint a thrombolysisprojekt keret\u00e9ben ell\u00e1tott betegeket. Eredm\u00e9nyek \u2013 A 78 nem protokoll szerinti ell\u00e1t\u00e1sban r\u00e9szes\u00fcl\u0151 betegn\u00e9l l\u00e1t\u00e1sjavul\u00e1st term\u00e9szetes lefoly\u00e1s eset\u00e9n 37%, konzervat\u00edv kezel\u00e9s mellett 47%, paracentesissel 47%-n\u00e1l l\u00e1ttunk. Szignifik\u00e1ns carotisstenosis n\u00e9gy, carotisdissectio egy, cardialis emboliaforr\u00e1s hat, \u00f3ri\u00e1ssejtes arteritis egy esetben igazol\u00f3dott; endarterectomi\u00e1n k\u00e9t beteg esett \u00e1t. A protokoll szerinti klinikai vizsg\u00e1latba n\u00e9gy, id\u0151ablakon bel\u00fcli betegb\u0151l h\u00e1rom egyezett bele, n\u00e1luk thrombolysis t\u00f6rt\u00e9nt. K\u00e9t betegnek javult a visusa, k\u00e9t betegn\u00e9l szignifik\u00e1ns carotisstenosis igazol\u00f3dott, \u00e9s endarterectomi\u00e1n estek \u00e1t, egy betegn\u00e9l novum pitvarfibrill\u00e1ci\u00f3 miatt antikoagul\u00e1l\u00e1st kezdt\u00fcnk. K\u00f6vetkeztet\u00e9s \u2013 A ter\u00e1pi\u00e1s id\u0151ablakon bel\u00fcl jelentkez\u0151 ACRO-betegek ritk\u00e1k, a thrombolysis hat\u00e1soss\u00e1g\u00e1nak meg\u00edt\u00e9l\u00e9s\u00e9hez nagyobb betegsz\u00e1m sz\u00fcks\u00e9ges. Az egys\u00e9ges vizsg\u00e1lati protokoll azonban egy\u00e9rtelm\u0171en el\u0151seg\u00edti az etiol\u00f3giai diagn\u00f3zist, \u00edgy a tov\u00e1bbi, ak\u00e1r s\u00falyosabb form\u00e1ban jelentkez\u0151 thromboemboli\u00e1s sz\u00f6v\u0151dm\u00e9nyek megel\u0151z\u00e9s\u00e9t.<\/jats:p>","DOI":"10.18071\/isz.77.0089","type":"journal-article","created":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T12:19:03Z","timestamp":1712665143000},"page":"89-96","source":"Crossref","is-referenced-by-count":0,"title":["Arteria centralis retinae elz\u00e1r\u00f3d\u00e1s thrombolysiskezel\u00e9se \u00e9s multidiszciplin\u00e1ris ell\u00e1t\u00e1sa a hagyom\u00e1nyos szem\u00e9szeti kezel\u00e9si form\u00e1kkal \u00f6sszehasonl\u00edtva"],"prefix":"10.18071","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9769-4111","authenticated-orcid":false,"given":"Szilvia","family":"Vajda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2481-321X","authenticated-orcid":false,"given":"Bence","family":"Gunda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3574-9973","authenticated-orcid":false,"given":"Krisztina","family":"Kn\u00e9zy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Barsi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2045-8451","authenticated-orcid":false,"given":"Csaba","family":"Varga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0885-736X","authenticated-orcid":false,"given":"P\u00e1l","family":"Maurovich-Horvat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8374-0500","authenticated-orcid":false,"given":"D\u00e1niel","family":"Bereczki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7330-0464","authenticated-orcid":false,"given":"Zolt\u00e1n Zsolt","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7411","published-online":{"date-parts":[[2024]]},"container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"original-title":[],"link":[{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/thrombolysis-treatment-and-multi-disciplinary-management-of-central-retinal-artery-occlusion-in-comparison-with-traditional-ophthalmological-treatment-options\/pdf-open","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T12:19:06Z","timestamp":1712665146000},"score":1,"resource":{"primary":{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/thrombolysis-treatment-and-multi-disciplinary-management-of-central-retinal-artery-occlusion-in-comparison-with-traditional-ophthalmological-treatment-options"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"references-count":0,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2024]]},"published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.18071\/isz.77.0089","relation":{},"ISSN":["0019-1442","2498-6208"],"issn-type":[{"type":"print","value":"0019-1442"},{"type":"electronic","value":"2498-6208"}],"subject":[],"published":{"date-parts":[[2024]]}}}