{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T04:09:47Z","timestamp":1749096587589,"version":"3.41.0"},"reference-count":0,"publisher":"Ideggyogyaszati Szemle Journal","issue":"5-6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:p>Background and purpose \u2013 Our aim\nwas to use visual evoked potentials (VEP)\nto evaluate changes in brain bioelectrical\nactivity in Hashimoto thyroiditis patients\nwith normal neurological examination\nand imaging findings and to correlate the\nevoked potential parameters with clinical\ndata.\nMethods \u2013 The study included 75 clinically\ndiagnosed Hashimoto thyroiditis patients\nand 45 healthy individuals who met the\nselection criteria. Demographic and clinical\ncharacteristics such as age, sex, disease\nduration, serum thyroid hormone levels,\nautoantibody titers, thyroid ultrasonography,\nbrain magnetic resonance imaging, and\nlevothyroxine dose used were recorded. VEP\ntests were performed in both groups. All\nparticipants provided informed consent.\nResults \u2013 Of the Hashimoto thyroiditis\npatients included in the study, 92% (n=69)\nwere female, the mean age was 40.3\u00b112.2\nyears, and the mean disease duration was\n5.7\u00b17.5 years (range: 0-40 years, median:\n4 years). Euthyroid patients showed\nsignificantly longer P100 latency difference\nand higher N75\/P100 amplitude than\nthe control group (p=0.014 and 0.007,\nrespectively). Elevated thyroid-stimulating\nhormone level was associated with longer\nN75 and P100 latencies.\nConclusion \u2013 Our results demonstrated\nthe presence of abnormal brain bioelectric\nactivity in Hashimoto thyroiditis patients\nwithout active neurological findings. These\neffects increase with disease severity and\nduration and necessitate the development\nof early treatment strategies to halt the\nprogressive autoimmune process.<\/jats:p>","DOI":"10.18071\/isz.78.0181","type":"journal-article","created":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T07:42:11Z","timestamp":1749022931000},"page":"181-188","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of visual evoked potentials in patients with Hashimoto thyroiditis"],"prefix":"10.18071","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5433-2006","authenticated-orcid":false,"given":"Pinar Bengi","family":"Boz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8807-6010","authenticated-orcid":false,"given":"Muhammet","family":"Ate\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9334-3285","authenticated-orcid":false,"given":"Murat","family":"Boz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7411","published-online":{"date-parts":[[2025]]},"container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"original-title":[],"link":[{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/evaluation-of-visual-evoked-potentials-in-patients-with-hashimoto-thyroiditis\/pdf-open","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T07:42:12Z","timestamp":1749022932000},"score":1,"resource":{"primary":{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/evaluation-of-visual-evoked-potentials-in-patients-with-hashimoto-thyroiditis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"references-count":0,"journal-issue":{"issue":"5-6","published-online":{"date-parts":[[2025]]},"published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.18071\/isz.78.0181","relation":{},"ISSN":["0019-1442","2498-6208"],"issn-type":[{"value":"0019-1442","type":"print"},{"value":"2498-6208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]}}}