{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T06:16:56Z","timestamp":1769753816385,"version":"3.49.0"},"reference-count":0,"publisher":"Ideggyogyaszati Szemle Journal","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Background and purpose\nTo assess the effectiveness of Gasserian ganglion block and pulsed radiofrequency in managing chronic cluster headache (CCH).\n\nMethods\nWe enrolled 38 patients with treatment-resistant CCH who were admitted between March 2020 and January 2024 and underwent Gasserian ganglion pulsed radiofrequency (PRF) combined with a ganglion block. Patients were followed up for six months, with pain severity assessed using the 0-10 Numerical Pain Rating Scale (NPRS).\n\nResults\nAmong 38 patients (mean age 30.8 \u00b1 8.6 years), the mean headache duration before treatment was 29.72 \u00b1 17.65 months, and patients reported an average of 19.11 \u00b1 2.01 headache days per month. Before the procedure, the mean NPRS score was 8.81 \u00b1 0.80, which significantly decreased to 4.13 \u00b1 3.74 post-treatment (p=0.001) and further declined to 3.38 \u00b1 1.59 at the six-month follow-up (p=0.002). Four patients became pain-free, while 13 did not benefit from the procedure. The mean number of headache days dropped to 6.40 \u00b1 4.22 per month (p&lt;0.001). Additionally, 24 patients required lower doses or fewer preventive medications, suggesting a sustained therapeutic benefit. The procedure had mild and temporary side effects, including pain on the day of injection, and localized discomfort. No serious complications were reported.\n\nConclusion\nOur results showed a significant reduction in pain and attack frequency with Gasserian ganglion block and PRF for treating CCH resistant to standard therapies, with many patients requiring less medication. The procedure was well-tolerated, with mild and temporary side effects; these findings suggest it may be a promising option for drug-resistant CCH. Future studies should include controlled trials for further evaluation.<\/jats:p>","DOI":"10.18071\/isz.79.0045","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T15:53:49Z","timestamp":1769702029000},"page":"45-52","source":"Crossref","is-referenced-by-count":0,"title":["The efficacy of Gasserian ganglion block and pulsed radiofrequency in the treatment of chronic cluster headache: A retrospective cohort study"],"prefix":"10.18071","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5221-5415","authenticated-orcid":false,"given":"Mustafa Kemal","family":"\u0130lik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5045-7082","authenticated-orcid":false,"given":"Faik","family":"\u0130lik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5309-1258","authenticated-orcid":false,"given":"Devrimsel Harika","family":"Ertem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7411","published-online":{"date-parts":[[2026]]},"container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"original-title":[],"link":[{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/the-efficacy-of-gasserian-ganglion-block-and-pulsed-radiofrequency-in-the-treatment-of-chronic-cluster-headache-a-retrospective-cohort-study\/pdf-open","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T15:53:51Z","timestamp":1769702031000},"score":1,"resource":{"primary":{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/the-efficacy-of-gasserian-ganglion-block-and-pulsed-radiofrequency-in-the-treatment-of-chronic-cluster-headache-a-retrospective-cohort-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"1-2","published-online":{"date-parts":[[2026]]},"published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.18071\/isz.79.0045","relation":{},"ISSN":["0019-1442","2498-6208"],"issn-type":[{"value":"0019-1442","type":"print"},{"value":"2498-6208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}