{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:53:06Z","timestamp":1774536786020,"version":"3.50.1"},"reference-count":0,"publisher":"Ideggyogyaszati Szemle Journal","issue":"3-4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>Bevezet\u00e9s\nAz elm\u00falt h\u00fasz \u00e9v sor\u00e1n, a betegs\u00e9glefoly\u00e1st m\u00f3dos\u00edt\u00f3 ter\u00e1pi\u00e1k b\u0151v\u00fcl\u00e9s\u00e9nek \u00e9s javul\u00f3 hat\u00e9konys\u00e1g\u00e1nak k\u00f6sz\u00f6nhet\u0151en, a sclerosis multiplexes (SM-) betegek \u00e9letmin\u0151s\u00e9ge \u00e9s \u00e9letkil\u00e1t\u00e1sai is javultak, a k\u00f3rk\u00e9p prevalenci\u00e1ja pedig \u2013 t\u00f6bb t\u00e9nyez\u0151 egy\u00fctthat\u00e1sak\u00e9nt \u2013 n\u0151tt. C\u00e9lunk a beteggondoz\u00e1s gyakorlat\u00e1ban bek\u00f6vetkezett v\u00e1ltoz\u00e1sok jellemz\u00e9se volt.\n\nM\u00f3dszerek\nA Semmelweis Egyetem Neurol\u00f3giai Klinik\u00e1n ell\u00e1tott \u00f6sszes ambul\u00e1ns \u00e9s j\u00e1r\u00f3beteg k\u00f6z\u00fcl kikerest\u00fck azokat, akikhez a 2006., 2012., 2016. \u00e9s 2022. napt\u00e1ri \u00e9vekben legal\u00e1bb egyszer az SM diagn\u00f3zis\u00e1t (G35 BNO-k\u00f3dot) r\u00f6gz\u00edtett\u00e9k. Az orvosi dokument\u00e1ci\u00f3 \u00e1ttekint\u00e9s\u00e9vel azonos\u00edtottuk a val\u00f3di SM-betegeket, \u00e9s r\u00f6gz\u00edtett\u00fck az abban az \u00e9vben a Klinik\u00e1n bennfekv\u0151k\u00e9nt t\u00f6lt\u00f6tt napjaik \u00e9s az ambul\u00e1ns megjelen\u00e9seik sz\u00e1m\u00e1t, illetve adott \u00e9vi kezel\u00e9s\u00fck hat\u00f3anyag\u00e1t.\n\nEredm\u00e9nyek\nA Klinik\u00e1n ell\u00e1tott SM-betegek l\u00e9tsz\u00e1ma 2006-ban 139 volt, amely 2022-re 514-re n\u0151tt. A vizsg\u00e1lt id\u0151szakban a kezdeti 21,6%-r\u00f3l a t\u00f6bbsz\u00f6r\u00f6s\u00e9re, 76,8%-ra emelkedett azon betegek ar\u00e1nya, akik az adott \u00e9vben legal\u00e1bb egyf\u00e9le betegs\u00e9glefoly\u00e1st m\u00f3dos\u00edt\u00f3 kezel\u00e9st kaptak. M\u00edg 2006-ban a betegek 54,7%-\u00e1t kellett az adott \u00e9vben legal\u00e1bb egyszer hospitaliz\u00e1lni az SM-mel \u00f6sszef\u00fcgg\u00e9sben, ez 2022-ben m\u00e1r csak a betegek \u00e1tlag 6%-\u00e1ra volt igaz, de ebben nagy k\u00fcl\u00f6nbs\u00e9g l\u00e1tszik a kezelt \u00e9s kezeletlen betegek k\u00f6zt (3,8% vs. 13,4%). Jelent\u0151sen megn\u0151tt az ambul\u00e1ns megjelen\u00e9sek abszol\u00fat \u00e9s egy f\u0151re es\u0151 \u00e9ves sz\u00e1ma (1,7-r\u0151l 5,1-re), az ut\u00f3bbi f\u0151leg a kezelt betegek k\u00f6z\u00f6tt.\n\nK\u00f6vetkeztet\u00e9s\nA nemzetk\u00f6zi \u00e9s hazai ir\u00e1nyelveknek megfelel\u0151en, az SM- betegek egyre nagyobb h\u00e1nyada r\u00e9szes\u00fcl immunmodul\u00e1ns kezel\u00e9sben, \u00e9s \u2013 v\u00e9lhet\u0151en ezzel \u00f6sszef\u00fcgg\u00e9sben \u2013 egyre kev\u00e9sb\u00e9 szorulnak hospitaliz\u00e1ci\u00f3ra, ugyanakkor t\u00f6bbsz\u00f6r\u00f6s\u00e9re n\u0151tt az SM-gondoz\u00e1s ambul\u00e1ns forgalma. E trend az ell\u00e1t\u00e1sszervez\u00e9sben lehet fontos szempont.<\/jats:p>","DOI":"10.18071\/isz.79.0103","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T13:58:41Z","timestamp":1774533521000},"page":"103-109","source":"Crossref","is-referenced-by-count":0,"title":["Paradigmav\u00e1lt\u00e1s a sclerosis multiplexes betegek gondoz\u00e1s\u00e1ban : A Semmelweis Egyetem Neuroimmunol\u00f3giai Centrum\u00e1nak 17 \u00e9ves adatai alapj\u00e1n"],"prefix":"10.18071","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5442-0794","authenticated-orcid":false,"given":"Anna","family":"Iljicsov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5366-0836","authenticated-orcid":false,"given":"J\u00e1nos","family":"B\u00edr\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3797-2191","authenticated-orcid":false,"given":"Zsolt","family":"Mezei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3182-4067","authenticated-orcid":false,"given":"D\u00e1niel","family":"Milanovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4437-0276","authenticated-orcid":false,"given":"N\u00e1rcis","family":"Tegze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1652-2407","authenticated-orcid":false,"given":"Magdolna","family":"Sim\u00f3","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7411","published-online":{"date-parts":[[2026]]},"container-title":["Ideggy\u00f3gy\u00e1szati szemle"],"original-title":[],"link":[{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/paradigm-shift-in-multiple-sclerosis-patient-care-at-the-center-of-neuro-immunology-semmelweis-university-data-of-17-years\/pdf-open","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T13:58:42Z","timestamp":1774533522000},"score":1,"resource":{"primary":{"URL":"https:\/\/elitmed.hu\/en\/publications\/clinical-neuroscience\/paradigm-shift-in-multiple-sclerosis-patient-care-at-the-center-of-neuro-immunology-semmelweis-university-data-of-17-years"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2026]]},"published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.18071\/isz.79.0103","relation":{},"ISSN":["0019-1442","2498-6208"],"issn-type":[{"value":"0019-1442","type":"print"},{"value":"2498-6208","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}