{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:32:12Z","timestamp":1793640732607,"version":"4.5.1"},"reference-count":33,"publisher":null,"issue":"1","license":[{"start":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T00:00:00Z","timestamp":1548633600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>\n                    <jats:underline>Purpose:<\/jats:underline>\n                    to assess the association between depression and all-cause mortality in patients with congestive heart failure (CHF) after cardiac resynchronization therapy (CRT).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>Materials and Methods.<\/jats:underline>\n                    We enrolled in this study 156 patients (mean age 55.3\u00b19.6 years) with CHF and implanted devices for CRT. Mean duration of follow-up was 51.6\u00b133.4 months. The Beck Depression Inventory (BDI) was used to evaluate depressive symptoms (DS); DS were considered absent for a score 0\u20139, mild to moderate \u2013 10\u201318, severe \u2013 \u226519. For assessment of association of DS and mortality we used multivariate Cox proportional hazards regression model with estimation of hazard ratios (HR) with 95 % confidence intervals (95 %CI).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>Results<\/jats:underline>\n                    . Average Beck Depression Inventory score was 12.4\u00b18.3. In 66 patients (42.3 %) there were no DS, 57 patients (36.5 %) had mild, and 33 (21.2 %) \u2013 severe DS. These groups did not differ by main clinical-functional and laboratory indicators. Among individuals without DS prevailed men (90.9 vs. 69.7 % among those with severe DS, p=0.007). Hypercholesterolemia was more frequent in patients with DS (63.3 vs. 43.9 % in patients without DS, p=0.02). During follow-up 33 patients died (21.2 %). Adjusted HR of death from all-causes for DS score as continuous parameter was 1.05, 95 % CI 1.01\u20131.09, p=0.02. Patients without DS were used as reference (HR=1.0) in analysis of categorical indicator. HR was 1.08, 95 % CI 0.46\u20132.54, p=0.9 in patients with mild, and 2.92, 95 % CI 1.17\u20137.32, p=0.02 \u2013 with severe DS.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:underline>Conclusion:<\/jats:underline>\n                    DS were associated with gender and hypercholesterolemia. Severe DS were independently associated with all-cause mortality in patients with CHF and implanted CRT devices.\n                  <\/jats:p>","DOI":"10.18087\/cardio.2019.1.10211","type":"journal-article","created":{"date-parts":[[2019,1,28]],"date-time":"2019-01-28T06:38:03Z","timestamp":1548657483000},"page":"5-11","source":"Crossref","is-referenced-by-count":10,"title":["Impact of Depressive Symptoms on All-Cause Mortality in Patients with Congestive Heart Failure After Cardiac Resynchronization Therapy"],"prefix":"10.68900","volume":"59","author":[{"given":"G. S.","family":"Pushkarev","sequence":"first","affiliation":[{"name":"Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V. A.","family":"Kuznetsov","sequence":"additional","affiliation":[{"name":"Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. A.","family":"Fisher","sequence":"additional","affiliation":[{"name":"Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. M.","family":"Soldatova","sequence":"additional","affiliation":[{"name":"Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0410. D.","family":"Sapozhnikova","sequence":"additional","affiliation":[{"name":"Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. N.","family":"Enina","sequence":"additional","affiliation":[{"name":"Tyumen Cardiology Research Center, Tomsk National Research Medical Center, Russian Academy of Science"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2019,1,28]]},"reference":[{"key":"ref1","unstructured":"Oganov R. G., Shalnova S. A., Kalinina A. M. Cardiovascular disease prevention: manual. Moscow: GEOTAR-Media 2009;216r. Russian (Oganov R.G., Shal'nova S.A., Kalinina A.M. Profilaktika serdechno-sosudistykh zabolevanii. Moskva: GEOTARMedia 2009; 216 c.)"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Piepoli M. F., Hoes A. W., Agewall S. et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. European Heart J 2016;37:2315\u20132381. DOI: 10.1093\/eurheartj\/ehw106.","DOI":"10.1093\/eurheartj\/ehw106"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Lichtman J. H, Bigger J. T., Blumenthal J. A. et al. 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Rol' tsitokinovoi agressii v razvitii khronicheskoi serdechnoi nedostatochnosti. Kubanskii nauchnyi meditsinskii vestnik 2011;4(127):29\u201331)."}],"container-title":["Kardiologiia"],"original-title":[],"link":[{"URL":"https:\/\/lib.ossn.ru\/jour\/article\/viewFile\/423\/341","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:17:15Z","timestamp":1793639835000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardio.elpub.ru\/jour\/article\/view\/423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,28]]},"references-count":33,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,1,28]]}},"URL":"https:\/\/doi.org\/10.18087\/cardio.2019.1.10211","relation":{},"ISSN":["2412-5660","0022-9040"],"issn-type":[{"value":"2412-5660","type":"electronic"},{"value":"0022-9040","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1,28]]}}}