{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:31:43Z","timestamp":1793640703802,"version":"4.5.1"},"reference-count":31,"publisher":null,"issue":"1","license":[{"start":{"date-parts":[[2020,2,6]],"date-time":"2020-02-06T00:00:00Z","timestamp":1580947200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>\n                    <jats:bold>Objective<\/jats:bold>\n                    Investigate the influence of the sympathetic denervation of the pulmonary trunk and the orifices of the\u00a0pulmonary arteries on the degree of pulmonary hypertension (PH) and outcomes of the surgical\u00a0treatment of atrial fibrillation (AF) in patients with mitral valve defects, complicated AF, and high PH.\n                    <jats:bold>Material and methods<\/jats:bold>\n                    We analyzed the surgical treatment of 140 patients with mitral valve defect, concomitant AF, and high\u00a0PH \u2013 pulmonary artery systolic pressure (PASP) gradient more than 40 mm Hg. The group of interest\u00a0included 51 patients (46 patients with severe mitral stenosis and five patients with grade 4 mitral\u00a0valve regurgitation). All patients underwent mitral valve correction (47 valve replacement surgeries\u00a0and 4 valve-sparing interventions), biatrial Maze IV procedure, and additionally, denervation of the\u00a0pulmonary trunk and the orifices of the pulmonary arteries. The control group included 89 patients\u00a0diagnosed with mitral valve defect, AF, and PH with PASP &gt; 40 mm Hg. However, unlike in patients\u00a0of interest, denervation of the pulmonary arteries was not performed.\n                    <jats:bold>Results<\/jats:bold>\n                    Circular radiofrequency denervation of the pulmonary trunk and the orifices of the pulmonary\u00a0arteries using a clamp-destructor is an effective and safe method, significantly reduces secondary PH\u00a0(p=0.018), promotes reverse remodeling of the heart chambers, left atrium in particular (p=0.01),\u00a0and improves outcomes of the Maze IV procedure (p=0.022) by restoring sinus rhythm in patients\u00a0with mitral valve defects, complicated AF, and high PH.\n                    <jats:bold>Conclusion<\/jats:bold>\n                    This technique must be studied further involving a more significant number of patients, analyzing\u00a0long-term results, and using this technique in patients with non-valvular causes of secondary PH.\n                  <\/jats:p>","DOI":"10.18087\/cardio.2020.1.n771","type":"journal-article","created":{"date-parts":[[2020,4,4]],"date-time":"2020-04-04T02:49:08Z","timestamp":1585968548000},"page":"35-42","source":"Crossref","is-referenced-by-count":8,"title":["Circular Sympathetic Pulmonary Artery Denervation in Cardiac Surgery Patients With Mitral Valve Defect, Atrial Fibrillation and High Pulmonary Hypertension"],"prefix":"10.68900","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1975-5521","authenticated-orcid":true,"given":"N. A.","family":"Trofimov","sequence":"first","affiliation":[{"name":"Chuvash Republican Cardiology Dispensary, Privolzhsky Research Medical University, Postgraduate Medical Institute, Federal Center for Traumatology, Orthopedics, and Endoprosthesis"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1757-5962","authenticated-orcid":true,"given":"A. P.","family":"Medvedev","sequence":"additional","affiliation":[{"name":"Privolzhsky Research Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2788-8762","authenticated-orcid":true,"given":"V. Y.","family":"Babokin","sequence":"additional","affiliation":[{"name":"Bashkir State Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7232-060X","authenticated-orcid":true,"given":"I. P.","family":"Efimova","sequence":"additional","affiliation":[{"name":"Chuvash Republican Cardiology Dispensary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9161-2066","authenticated-orcid":true,"given":"V. A.","family":"Kichigin","sequence":"additional","affiliation":[{"name":"Chuvash Republican Cardiology Dispensary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. G.","family":"Dragunov","sequence":"additional","affiliation":[{"name":"Chuvash Republican Cardiology Dispensary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5605-0128","authenticated-orcid":true,"given":"A. V.","family":"Nikolskii","sequence":"additional","affiliation":[{"name":"Privolzhsky Research Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. G.","family":"Tabaev","sequence":"additional","affiliation":[{"name":"Chuvash Republican Cardiology Dispensary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. I.","family":"Preobrazenskii","sequence":"additional","affiliation":[{"name":"Chuvash Republican Cardiology Dispensary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2020,2,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Sulimov V.A., Lishuta A.S. Prospects of treatment of patients with atrial fibrillation. Rational Pharmacotherapy in Cardiology. 2011;7(3):323\u201333. [Russian]","DOI":"10.20996\/1819-6446-2011-7-3-323-333"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Trofimov N.A., Medvedev A.P., Babokin V.\u0415., Demarin O.I., Zhamlihanov N.H., Dragunov A.G. et al. 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