{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:32:32Z","timestamp":1793640752635,"version":"4.5.1"},"reference-count":18,"publisher":null,"issue":"11","license":[{"start":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T00:00:00Z","timestamp":1606953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>\n                    <jats:italic>Aim\u00a0\u00a0\u00a0\u00a0\u00a0<\/jats:italic>\n                    To evaluate results of myomectomy by intraventricular pressure gradients (IVPG) and blood flows in patients with obstructive hypertrophic cardiomyopathy (OHCMP).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Material and methods\u00a0<\/jats:italic>\n                    The study included a total of 76 subjects, 42 patients with OHCMP (mean age, 39\u00b17 years) and 34 healthy volunteers (mean age, 41\u00b13 years). Prior to and after myomectomy, transthoracic echocardiography was performed and followed by digital image processing and calculation of IVPG and left ventricular (LV) vortex flows. Vector analysis was used to estimate the myocardial displacement rate (V), vortex flows, and LV apex-to-base pressure gradients.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    The study showed a dynamic decrease in the LV apex-to-outflow IVPG by more than 50% and recovery of myocardial contraction velocity in the septal area (\u0440&lt;0.001). The decrease in LV cavity pressure gradient serves as an index for evaluating the effectiveness of OHCMP correction. Myomectomy reduces the load on the myocardium and abolishes mitral valve regurgitation with improvement of LV blood flows as also evidenced by the dynamics of long axis velocity change during the cardiac cycle (dL\u200a\/\u200adt) and the myocardial contraction velocity (V).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusion\u00a0\u00a0\u00a0\u00a0\u00a0<\/jats:italic>\n                    Effectiveness of the surgical correction of OHCMP is based on the dynamics of myocardial contraction velocities, vortex blood flows, and a decrease in LV apex-to-base IVPG.\n                  <\/jats:p>","DOI":"10.18087\/cardio.2020.11.n1245","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T03:30:07Z","timestamp":1611545407000},"page":"66-75","source":"Crossref","is-referenced-by-count":1,"title":["Echocardiography in the Assessment of Intraventricular Flows and Pressure Gradients in Obstructive Hypertrophic Cardiomyopathy"],"prefix":"10.68900","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1535-5982","authenticated-orcid":true,"given":"V. \u0410.","family":"Sandrikov","sequence":"first","affiliation":[{"name":"Scientific Institution \u201cPetrovsky national research centre of surgery\u201d, Moscow"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6165-6474","authenticated-orcid":true,"given":"T. Yu.","family":"Kulagina","sequence":"additional","affiliation":[{"name":"Scientific Institution \u201cPetrovsky national research centre of surgery\u201d, Moscow"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4399-0716","authenticated-orcid":true,"given":"E. Yu.","family":"Van","sequence":"additional","affiliation":[{"name":"Scientific Institution \u201cPetrovsky national research centre of surgery\u201d, Moscow"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. V.","family":"Gavrilov","sequence":"additional","affiliation":[{"name":"Moscow State University M.V. Lomonosov, Moscow"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2020,12,3]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Brian A. Houston and Gerin R. Stevens, - Hypertrophic Cardiomyopathy: A Review. 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N Engl J Med 2003; 348: 295-303. doi:10.1056\/NEJMoa021332","DOI":"10.1056\/NEJMoa021332"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Maron BJ, Towbin JA., Thiene G., Antzelevitch C. et al. - Contemporary Definitions and Classification of the Cardiomyopathies: An American Heart Association Scientific Statement From the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention\/ Circulation \u22122006.- 113. \u2014 \u0420.1807-16 DOI: 10.1161\/CIRCULATIONAHA.106.174287","DOI":"10.1161\/CIRCULATIONAHA.106.174287"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Merrill, Walter H. et al. \u201cLong-lasting improvement after septal myectomy for hypertrophic obstructive cardiomyopathy.\u201d The Annals of thoracic surgery 69 6 (2000): 1732-5; discussion 1735-6 DOI:10.1016\/S0003-4975(00)01314-X","DOI":"10.1016\/S0003-4975(00)01314-X"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Morrow AG, Reitz BA, Epstein SE, et al. Operative treatment in hypertrophic subaortic stenosis. Techniques, and the results of pre and postoperative assessments in 83 patients. Circulation. 1975;52(1):88-102. doi:10.1161\/01.cir.52.1.88 doi:10.1161\/01.cir.52.1.88","DOI":"10.1161\/01.CIR.52.1.88"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Hensley N, Dietrich J, Nyhan D, Mitter N, Yee MS, Brady M. Hypertrophic cardiomyopathy: a review. Anesth Analg. 2015;120(3):554-569. doi:10.1213\/ANE.0000000000000538","DOI":"10.1213\/ANE.0000000000000538"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Nishimura RA, Ommen SR, Tajik AJ. Cardiology patient page. Hypertrophic cardiomyopathy: a patient perspective. Circulation. 2003;108(19):e133-e135. doi:10.1161\/01.CIR.0000097621.97566.96","DOI":"10.1161\/01.CIR.0000097621.97566.96"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Hong GR, Pedrizzetti G, Tonti G, et al. Characterization and quantification of vortex flow in the human left ventricle by contrast echocardiography using vector particle image velocimetry. JACC Cardiovasc Imaging. 2008;1(6):705-717. doi:10.1016\/j.jcmg.2008.06.008","DOI":"10.1016\/j.jcmg.2008.06.008"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Robbins RC, Stinson EB. Long-term results of left ventricular myotomy and myectomy for obstructive hypertrophic cardiomyopathy. J Thorac Cardiovasc Surg. 1996;111(3):586-594. doi:10.1016\/s0022-5223(96)70310-0","DOI":"10.1016\/S0022-5223(96)70310-0"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Sengupta PP, Pedrizzetti G, Kilner PJ, et al. Emerging trends in CV flow visualization. JACC Cardiovasc Imaging. 2012;5(3):305-316. doi:10.1016\/j.jcmg.2012.01.003","DOI":"10.1016\/j.jcmg.2012.01.003"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Panaich SS, Badheka AO, Chothani A, et al. Results of ventricular septal myectomy and hypertrophic cardiomyopathy (from Nationwide Inpatient Sample [1998-2010]). Am J Cardiol. 2014;114(9):1390-1395. doi:10.1016\/j.amjcard.2014.07.075","DOI":"10.1016\/j.amjcard.2014.07.075"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Tanaka M, Sakamoto T, Sugawara S, et al. Blood flow structure and dynamics, and ejection mechanism in the left ventricle: analysis using echo-dynamography. J Cardiol. 2008;52(2):86-101. doi:10.1016\/j.jjcc.2008.05.005","DOI":"10.1016\/j.jjcc.2008.05.005"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Lynne Williams, Harry Rakowski - Predicting the Future in Hypertrophic Cardiomyopathy: From Histopathology To Flow To Function 25 (2) : 190\u2013193 FEB 2012 (Journal of the American Society of Echocardiography) DOI: https:\/\/doi.org\/10.1016\/j.echo.2011.12.017","DOI":"10.1016\/j.echo.2011.12.017"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Wigle ED, Rakowski H, Kimball BP, Williams WG. Hypertrophic cardiomyopathy. Clinical spectrum and treatment. Circulation. 1995;92(7):1680-1692. doi:10.1161\/01.cir.92.7.1680","DOI":"10.1161\/01.CIR.92.7.1680"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"A.M. Yatchenko, V.A. Sandrikov, T. Yu. 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