{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:31:44Z","timestamp":1793640704101,"version":"4.5.1"},"reference-count":31,"publisher":null,"issue":"3","license":[{"start":{"date-parts":[[2020,5,3]],"date-time":"2020-05-03T00:00:00Z","timestamp":1588464000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>LEOPARD syndrome with multiple lentigines (cardiomyopathic lentiginosis) is a rare, genetically predetermined disease with autosomal dominant inheritance. Prevalence of this syndrome is unknown. One of pathognomonic clinical manifestations of this syndrome is the presence of multiple lentiginous pigment spots all over the body. The most common cardiac manifestation (approximately 80%) is myocardial hypertrophy. We presented a rare clinical case of detecting LEOPARD syndrome with multiple lentigines in a 32-year old female patient with major manifestations evident as pronounces morpho-functional alterations, myocardial hypertrophy, and heart rhythm disorders.<\/jats:p>","DOI":"10.18087\/cardio.2020.3.n944","type":"journal-article","created":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T04:01:32Z","timestamp":1588824092000},"page":"137-141","source":"Crossref","is-referenced-by-count":3,"title":["LEOPARD syndrome"],"prefix":"10.68900","volume":"60","author":[{"given":"S. A.","family":"Gabrusenko","sequence":"first","affiliation":[{"name":"Russian Cardiology Research and Production Complex, Ministry of Health of Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Saidova","sequence":"additional","affiliation":[{"name":"Russian Cardiology Research and Production Complex, Ministry of Health of Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O. V.","family":"Stukalova","sequence":"additional","affiliation":[{"name":"Russian Cardiology Research and Production Complex, Ministry of Health of Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kh. M.","family":"Dzaurova","sequence":"additional","affiliation":[{"name":"Russian Cardiology Research and Production Complex, Ministry of Health of Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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[Russian: Rizun L.I., Voronova T.S., Frolova Yu.V., Raskin V.V., Rumyantseva V.A., Zaklyaz'minskaya E.V. i dr. Progressiruyushchaya gipertroficheskaya kardiomiopatiya pri sindrome LEOPARD. Khirurgiya. Zhurnal imeni N.I. Pirogova. 2012;12:56-61]","DOI":"10.3103\/S1066369X12120079"},{"key":"ref25","unstructured":"Golousenko I.Yu., Glebova L.I., Kuleshov A.N. LEOPARD syndrome, LAMB syndrome or disseminated lentigines? Consilium Medicum. Dermatology. 2017;1:48\u201350. [Russian: Golousenko I.Yu., Glebova L.I., Kuleshov A.N. Sindrom LEOPARD, sindrom LAMB ili disseminirovannyi lentiginoz? Dermatologiya. Prilizhenie k zhurnalu Consilium Medicum. 2017;1:48-50]"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Sanaani A, Fuisz A. Cardiac Magnetic Resonance for Diagnosis and Risk Stratification. Cardiology Clinics. 2019;37(1):27\u201333. 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