{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:30:50Z","timestamp":1793640650675,"version":"4.5.1"},"reference-count":11,"publisher":null,"issue":"4","license":[{"start":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T00:00:00Z","timestamp":1651276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>In cardiological practice, there may be patients with chest pain and heart failure of a specific etiology, including an association with cardiovascular syphilis. This article describes a 49-year patient with chest pain, heart failure, and neurological symptoms associated with ongoing tertiary syphilis. The history included an antisyphilitic treatment 30 years before the current hospitalization. Further evaluation confirmed neuro- and cardiovascular syphilis with severe aortic regurgitation and syphilitic myocarditis. Tertiary syphilis is a rare but relevant challenge for various medical specialists, including cardiologists. This pathology requires increased medical alertness and interdisciplinary interaction for early diagnosis, effective and safe treatment, and improved prognosis.<\/jats:p>","DOI":"10.18087\/cardio.2022.4.n1516","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T08:55:16Z","timestamp":1652691316000},"page":"73-76","source":"Crossref","is-referenced-by-count":0,"title":["Chest pain and chronic heart failure as a manifestation of tertiary syphilis: clinical case"],"prefix":"10.68900","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7479-418X","authenticated-orcid":true,"given":"E. V.","family":"Reznik","sequence":"first","affiliation":[{"name":"Pirogov Russian National Research Medical University (RNRMU); City Clinical Hospital n. a. V.M. Buyanov; City Clinical Hospital #31; City Clinical Hospital n. a. V.P. Demikhov"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3372-7727","authenticated-orcid":true,"given":"N. M.","family":"Dubinin","sequence":"additional","affiliation":[{"name":"Pirogov Russian National Research Medical University (RNRMU)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8955-9625","authenticated-orcid":true,"given":"E.","family":"Khalatova","sequence":"additional","affiliation":[{"name":"Pirogov Russian National Research Medical University (RNRMU)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0950-7487","authenticated-orcid":true,"given":"I. S.","family":"Nazarov","sequence":"additional","affiliation":[{"name":"Pirogov Russian National Research Medical University (RNRMU)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5643-1059","authenticated-orcid":true,"given":"V. A.","family":"Kac","sequence":"additional","affiliation":[{"name":"City Clinical Hospital n. a. V.M. Buyanov"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2314-6523","authenticated-orcid":true,"given":"L. V.","family":"Brilyov","sequence":"additional","affiliation":[{"name":"City Clinical Hospital n. a. V.M. Buyanov"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0429-3117","authenticated-orcid":true,"given":"A. S.","family":"Dvornikov","sequence":"additional","affiliation":[{"name":"Pirogov Russian National Research Medical University (RNRMU)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2022,4,30]]},"reference":[{"key":"ref1","unstructured":"Aleksandrova G.A., Golubev N.A., Tyurina E.M., Ogryzko E.V., Zalevskaya O.V., Avdeeva L.N. Socially significant diseases of the Russian population in 2018 (Statistical materials). Moscow 2019. Av. at: https:\/\/minzdrav.gov.ru\/ministry\/61\/22\/stranitsa-979\/statisticheskie-i-informatsionnye-materialy\/statisticheskiy-sbornik-2018-god."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Kubanova A.A., Kubanov A.A., Melekhina L.E. Incidence of Syphilis in the Russian Federation Over the Period 2006\u20132016. Vestnik dermatologii i venerologii. 2017;93(5):16\u201325. DOI: 10.25208\/0042-4609-2017-93-5-16-25","DOI":"10.25208\/0042-4609-2017-93-5-16-25"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Tumanova E.L., Loseva O.K., Kvizhinadze G.N., Alekseev V.G. Combined syphilitic lesion of the cardiovascular and nervous systems. Russian Journal of Clinical Dermatology and Venereology. 2015;14(2):42\u20135. DOI: 10.17116\/klinderma201514242-47","DOI":"10.17116\/klinderma201514242-47"},{"key":"ref4","unstructured":"Skripkin Yu.K., Shostak N.A., Khamaganova I.V., Dvornikov A.S., Koshina M.V. Neurosyphilis in a patient with scleroderma. Russian Journal of Skin and Venereal Diseases. 2005;2:56\u20138."},{"key":"ref5","unstructured":"Loseva O.K., Chistiakova T.V., Lebedeva G.A., Kisel\u2019 O.V. The detection and diagnosis of cardiovascular syphilis in Moscow. Russian Journal of Clinical Dermatology and Venereology. 2013;11(3):38\u201347."},{"key":"ref6","unstructured":"Potekaev N.N., Loseva O.K., Frigo N.V., Kvizhinadze G.N., Zhukovskiy R.O. 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Russian Journal of Clinical Dermatology and Venereology. 2016;15(4):19\u201325. DOI: 10.17116\/klinderma201615419-25","DOI":"10.17116\/klinderma201615419-25"},{"key":"ref10","unstructured":"Kisel\u2019 O.V., Loseva O.K., Prelovskaya G.Yu. Myocardial infarction and syphilis. Consilium Medicum. 2010;12(1):89\u201390."},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Brown AP, Dawkins KD, Parker DJ. \u2018Late\u2019 manifestations of cardiovascular syphilis occurring in a young man. Heart. 1987;58(4):405\u20138. DOI: 10.1136\/hrt.58.4.405","DOI":"10.1136\/hrt.58.4.405"}],"container-title":["Kardiologiia"],"original-title":[],"link":[{"URL":"https:\/\/lib.ossn.ru\/jour\/article\/viewFile\/1516\/1206","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:16:18Z","timestamp":1793639778000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardio.elpub.ru\/jour\/article\/view\/1516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,30]]},"references-count":11,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,4,30]]}},"URL":"https:\/\/doi.org\/10.18087\/cardio.2022.4.n1516","relation":{},"ISSN":["2412-5660","0022-9040"],"issn-type":[{"value":"2412-5660","type":"electronic"},{"value":"0022-9040","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4,30]]}}}