{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:31:34Z","timestamp":1793640694186,"version":"4.5.1"},"reference-count":16,"publisher":null,"issue":"4","license":[{"start":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T00:00:00Z","timestamp":1651276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>\n                    <jats:italic>Aim<\/jats:italic>\n                    \u00a0 \u00a0To compare myocardial deformation properties in patients with heart failure (HF) with preserved left ventricular ejection fraction (HFpEF) and in healthy volunteers at rest and during a dynamometric test; to determine a possibility of using this method for diagnosing HSpEF.\n                    <jats:italic>Material and methods<\/jats:italic>\n                    \u00a0 \u00a0STE with simultaneous electrocardiogram recording was performed for patients with HSpEF and healthy volunteers of the control group at rest and during a dynamometric test. The subjects were instructed to maintain a submaximal compression of a hand dynamometer for 3 min and to apply a maximum effort during the last 30 sec while continuing to breathe regularly. Concentrations of markers for myocardial injury and HF were measured. Statistical analytical methods are provided in Results. For other calculations, a MS Office (Microsoft Excel) application software package was used.\n                    <jats:italic>Results<\/jats:italic>\n                    \u00a0 \u00a0Differences in myocardial deformation variables between healthy volunteers and HF patients were more obvious during exercise, including changes of the variables from the resting values. As compared with the control group, patients with HFpEF had considerable deviations of the heart rate and the left ventricular global longitudinal strain (GLSLV) (significance of differences calculated with ANOVA was higher than 95% and 80%; p&lt;0.05 and p&lt;0.2, respectively). Patients with a significant change in the strain, regardless of the direction of the change, showed a decrease in the left ventricular ejection fraction (EFLV) during the test with a probability above 95% according to the Fischer test. Also, patients with HFpEF had higher concentrations of N-terminal pro-brain natriuretic peptide and symptoms of HF. Compared to evaluation of overall GLSLV, calculation of deformation variables by segment detected more differences between patients with HFpEF and control subjects.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    \u00a0 \u00a0STE with a dynamometric test is an effective, noninvasive method for diagnosing HFpEF that is easy to perform in the outpatient conditions.\n                  <\/jats:p>\n                  <jats:p>\u00a0<\/jats:p>","DOI":"10.18087\/cardio.2022.4.n1804","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T08:55:16Z","timestamp":1652691316000},"page":"36-43","source":"Crossref","is-referenced-by-count":0,"title":["Applicability of the load dynamometric test and speckle tracking echocardiography in the heart failure with preserved ejection fraction diagnosis"],"prefix":"10.68900","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4239-9550","authenticated-orcid":true,"given":"E. K.","family":"Serezhina","sequence":"first","affiliation":[{"name":"LLC \u201cIMC SOGAZ\u201d"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6115-7923","authenticated-orcid":true,"given":"A. G.","family":"Obrezan","sequence":"additional","affiliation":[{"name":"LLC \u201cIMC SOGAZ\u201d"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2022,4,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Roger VL. Epidemiology of Heart Failure: A Contemporary Perspective. Circulation Research. 2021;128(10):1421\u201334. DOI: 10.1161\/CIRCRESAHA.121.318172","DOI":"10.1161\/CIRCRESAHA.121.318172"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Ratchford SM, Clifton HL, La Salle DT, Broxterman RM, Lee JF, Ryan JJ et al. Cardiovascular responses to rhythmic handgrip exercise in heart failure with preserved ejection fraction. Journal of Applied Physiology. 2020;129(6):1267\u201376. DOI: 10.1152\/japplphysiol.00468.2020","DOI":"10.1152\/japplphysiol.00468.2020"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Yancy CW, Jessup M, Bozkurt B, Butler J, Casey DE, Colvin MM et al. 2017 ACC\/AHA\/HFSA Focused Update of the 2013 ACCF\/AHA Guideline for the Management of Heart Failure: a report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. Journal of the American College of Cardiology. 2017;70(6):776\u2013803. DOI: 10.1016\/j.jacc.2017.04.025","DOI":"10.1161\/CIR.0000000000000509"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, B\u00f6hm M et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal. 2021;42(36):3599\u2013726. DOI: 10.1093\/eurheartj\/ehab368","DOI":"10.1093\/eurheartj\/ehab368"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Gudieva Kh.M., Safarova A.F., Kobalava Zh.D. Application of the HFA-PEFF algorithm for diagnosis of heartfailure with preserved left ventricular ejection fraction. Clinical pharmacology and therapy. 2020;29(2):47\u201350. DOI: 10.32756\/0869-5490-2020-2-47-50","DOI":"10.32756\/0869-5490-2020-2-47-50"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Kap\u0142on-Cie\u015blicka A, Kupczy\u0144ska K, Dobrowolski P, Michalski B, Jaguszewski MJ, Banasiak W et al. On the search for the right definition of heart failure with preserved ejection fraction. Cardiology Journal. 2020;27(5):449\u201368. DOI: 10.5603\/CJ.a2020.0124","DOI":"10.5603\/CJ.a2020.0124"},{"key":"ref7","unstructured":"Serezhina E.K., Obrezan A.G. New imaging techniques in the diagnosis of heart failure with preserved ejection fraction. Russian Medical Journal. Medical Review. 2019;3(1\u20132):52\u20136."},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Smiseth OA, Torp H, Opdahl A, Haugaa KH, Urheim S. Myocardial strain imaging: how useful is it in clinical decision making? European Heart Journal. 2016;37(15):1196\u2013207. DOI: 10.1093\/eurheartj\/ehv529","DOI":"10.1093\/eurheartj\/ehv529"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Potter E, Marwick TH. Assessment of Left Ventricular Function by Echocardiography: The Case for Routinely Adding Global Longitudinal Strain to Ejection Fraction. JACC: Cardiovascular Imaging. 2018;11(2 Pt 1):260\u201374. DOI: 10.1016\/j.jcmg.2017.11.017","DOI":"10.1016\/j.jcmg.2017.11.017"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Weiner RB, Weyman AE, Kim JH, Wang TJ, Picard MH, Baggish AL. The impact of isometric handgrip testing on left ventricular twist mechanics: Handgrip testing and left ventricular twist. The Journal of Physiology. 2012;590(20):5141\u201350. DOI: 10.1113\/jphysiol.2012.236166","DOI":"10.1113\/jphysiol.2012.236166"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Mitchell C, Rahko PS, Blauwet LA, Canaday B, Finstuen JA, Foster MC et al. Guidelines for Performing a Comprehensive Transthoracic Echocardiographic Examination in Adults: Recommendations from the American Society of Echocardiography. Journal of the American Society of Echocardiography. 2019;32(1):1\u201364. DOI: 10.1016\/j.echo.2018.06.004","DOI":"10.1016\/j.echo.2018.06.004"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Hashemi D, Motzkus L, Blum M, Kraft R, Tanacli R, Tahirovic E et al. Myocardial deformation assessed among heart failure entities by cardiovascular magnetic resonance imaging. ESC Heart Failure. 2021;8(2):890\u20137. DOI: 10.1002\/ehf2.13193","DOI":"10.1002\/ehf2.13193"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Baicu CF, Zile MR, Aurigemma GP, Gaasch WH. Left ventricular systolic performance, function, and contractility in patients with diastolic heart failure. Circulation. 2005;111(18):2306\u201312. DOI: 10.1161\/01.CIR.0000164273.57823.26","DOI":"10.1161\/01.CIR.0000164273.57823.26"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Kubiak, Ciarka, Biniecka, Ceranowicz. Right Heart Catheterization \u2013 Background, Physiological Basics, and Clinical Implications. Journal of Clinical Medicine. 2019;8(9):1331. DOI: 10.3390\/jcm8091331","DOI":"10.3390\/jcm8091331"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Wdowiak-Okrojek K, Wejner-Mik P, Kasprzak JD, Lipiec P. Recovery of regional systolic and diastolic myocardial function after acute myocardial infarction evaluated by two-dimensional speckle tracking echocardiography. Clinical Physiology and Functional Imaging. 2019;39(2):177\u201381. DOI: 10.1111\/cpf.12553","DOI":"10.1111\/cpf.12553"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Helle-Valle T, Crosby J, Edvardsen T, Lyseggen E, Amundsen BH, Smith H-J et al. New Noninvasive Method for Assessment of Left Ventricular Rotation: Speckle Tracking Echocardiography. Circulation. 2005;112(20):3149\u201356. 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