{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:31:51Z","timestamp":1793640711026,"version":"4.5.1"},"reference-count":29,"publisher":null,"issue":"12","license":[{"start":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T00:00:00Z","timestamp":1703548800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>\n                    <jats:italic>Aim<\/jats:italic>\n                    \u00a0\u00a0\u00a0\u00a0\u00a0 Prospective assessment of the nature of cardiac injury in patients with post-COVID syndrome according to contrast-enhanced MRI in routine clinical practice.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Material and methods<\/jats:italic>\n                    \u00a0 106 previously unvaccinated patients were evaluated. 62 (58.5%) of them were women with complaints that persisted after COVID-19 (median age, 57.5 [49; 64] years). In addition to standard indexes, markers of inflammation and myocardial injury were determined, and cardiac contrast-enhanced MRI was performed in each patient.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    The median time from the onset of COVID-19 to cardiac MRI was 112.5 [75; 151] days. The nature of cardiac injury according to MRI in patients with post-COVID syndrome was complex and included a decrease in left ventricular (LV) and right ventricular ejection fraction, pericardial effusion, and pathological foci of late and early contrast enhancement at various locations. In 29 (27.4%) cases, there was a combination of any two signs of heart injury. In 28 (26.4%) patients with focal myocardial injury during the acute phase of COVID-19, hydroxychloroquine and tocilizumab were administered significantly more frequently, but antiviral drugs were administered less frequently. The presence of focal myocardial injury was associated with pathological LV remodeling.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusion<\/jats:italic>\n                    \u00a0\u00a0\u00a0\u00a0\u00a0 According to contrast-enhanced cardiac MRI, at least 27.4% of patients with post-COVID syndrome may have signs of cardiac injury in various combinations, and in 26.4% of cases, foci of myocardial injury accompanied by LV remodeling are detected. The nature of heart injury after COVID-19 depends on the premorbid background, characteristics of the course of the infectious process, and the type of prescribed therapy. An algorithm for evaluating patients with post-COVID syndrome is proposed.\n                  <\/jats:p>\n                  <jats:p>\u00a0<\/jats:p>","DOI":"10.18087\/cardio.2023.12.n2268","type":"journal-article","created":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T06:11:05Z","timestamp":1703830265000},"page":"46-53","source":"Crossref","is-referenced-by-count":0,"title":["Combined Heart Injuries on the Data of Contrast-Enhanced Cardiac Magnetic Resonance Imaging in Patients With Post-Covid Syndrome"],"prefix":"10.68900","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3539-026X","authenticated-orcid":true,"given":"R. A.","family":"Khokhlov","sequence":"first","affiliation":[{"name":"Burdenko Voronezh State Medical University, Voronezh;\r\nVoronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. N.","family":"Lipovka","sequence":"additional","affiliation":[{"name":"Burdenko Voronezh State Medical University, Voronezh;\r\nVoronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. V.","family":"Dubrovina","sequence":"additional","affiliation":[{"name":"Voronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I. A.","family":"Lobas","sequence":"additional","affiliation":[{"name":"Voronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. V.","family":"Tribuntseva","sequence":"additional","affiliation":[{"name":"Burdenko Voronezh State Medical University, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. G.","family":"Prozorova","sequence":"additional","affiliation":[{"name":"Burdenko Voronezh State Medical University, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. I.","family":"Arzamasceva","sequence":"additional","affiliation":[{"name":"Burdenko Voronezh State Medical University, Voronezh;\r\nVoronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. R.","family":"Khokhlov","sequence":"additional","affiliation":[{"name":"Good Samaritan Hospital, Cincinnati, Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. V.","family":"Yarmonova","sequence":"additional","affiliation":[{"name":"Voronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. V.","family":"Zarechnova","sequence":"additional","affiliation":[{"name":"Voronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. A.","family":"Kuleshova","sequence":"additional","affiliation":[{"name":"Voronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. A.","family":"Shaley","sequence":"additional","affiliation":[{"name":"Voronezh Regional Clinical Consulting and Diagnostic Center, Voronezh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2023,12,26]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Basso C, Leone O, Rizzo S, De Gaspari M, van der Wal AC, Aubry M-C et al. Pathological features of COVID-19-associated myocardial injury: a multicentre cardiovascular pathology study. European Heart Journal. 2020;41(39):3827\u201335. 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