{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:31:56Z","timestamp":1793640716801,"version":"4.5.1"},"reference-count":12,"publisher":null,"issue":"2","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>\n                    <jats:italic>Aim<\/jats:italic>\n                    \u00a0 \u00a0Pericardial effusion is relatively common in daily clinical practice. To our knowledge, no study to date has been conducted on any laboratory parameter that predicts mortality in patients presenting with pericardial effusion. The present study evaluated the prognostic factors of patients with moderate to large pericardial effusions requiring pericardiocentesis.\n                    <jats:italic>Material and methods<\/jats:italic>\n                    \u00a0 \u00a0This retrospective study included 156 patients who underwent pericardiocentesis in our hospital between 2013 and 2022.\n                    <jats:italic>Results<\/jats:italic>\n                    \u00a0 \u00a073 of the patients (46.8 %) survived. Nonsurvivors had hypoalbuminemia more often than survivors (p&lt;0.001). Median follow-up time in non-survivors was 274.5 [4.0\u20133507.0] days, while median follow-up time in survivors was 1490.0 [109.0\u20133209.0]. In-hospital mortality was seen in only 8 patients. The median neutrophil \/ lymphocyte ratio was significantly lower in survivors than nonsurvivors (p=0.005). The ROC curve analysis showed that the neutrophil \/ lymphocyte ratio was higher than 4.49, with sensitivity and specificity rates of 78.57 % and 51.75 % in predicting mortality (AUC=0.622, 95 % confidence interval: 0.541\u20130.698, p=0.013).\n                    <jats:italic>Conclusions \u00a0<\/jats:italic>\n                    \u00a0The present study showed that the neutrophil \/ lymphocyte ratio and hypoalbuminemia, which are laboratory values at the time of admission, albumin in the pericardial fluid, and malignant pathology all play roles in the prognosis of pericardial effusion requiring pericardiocentesis.\n                  <\/jats:p>","DOI":"10.18087\/cardio.2025.2.n2324","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T09:32:11Z","timestamp":1741339931000},"page":"42-47","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic Factors in Moderate-to-Large Pericardial Effusion Requiring Pericardiocentesis. A Single-Center Retrospective Study"],"prefix":"10.68900","volume":"65","author":[{"given":"Sevil","family":"G\u00fcla\u015ft\u0131","sequence":"first","affiliation":[{"name":"Adnan Menderes University School of Medicine, Department of Cardiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berk","family":"Mutlu","sequence":"additional","affiliation":[{"name":"Adnan Menderes University School of Medicine, Department of Cardiology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cemil","family":"Zencir","sequence":"additional","affiliation":[{"name":"Adnan Menderes University School of Medicine, Department of Cardiology"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Imazio M, Trinchero R. Triage and management of acute pericarditis. International Journal of Cardiology. 2007;118(3):286\u201394. DOI: 10.1016\/j.ijcard.2006.07.100","DOI":"10.1016\/j.ijcard.2006.07.100"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Imazio M, Mayosi BM, Brucato A, Markel G, Trinchero R, Spodick DH et al. Triage and management of pericardial effusion. Journal of Cardiovascular Medicine. 2010;11(12):928\u201335. DOI: 10.2459\/JCM.0b013e32833e5788","DOI":"10.2459\/JCM.0b013e32833e5788"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Imazio M, Adler Y. Management of pericardial effusion. European Heart Journal. 2013;34(16):1186\u201397. DOI: 10.1093\/eurheartj\/ehs372","DOI":"10.1093\/eurheartj\/ehs372"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Colombo A, Olson HG, Egan J, Gardin JM. Etiology and prognostic implications of a large pericardial effusion in men. Clinical Cardiology. 1988;11(6):389\u201394. DOI: 10.1002\/clc.4960110606","DOI":"10.1002\/clc.4960110606"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"S\u00f8gaard KK, Farkas DK, Ehrenstein V, Bhaskaran K, B\u00f8tker HE, S\u00f8rensen HT. Pericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality. Circulation. 2017;136(11):996\u20131006. DOI: 10.1161\/CIRCULATIONAHA.116.024041","DOI":"10.1161\/CIRCULATIONAHA.116.024041"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Light RW, Macgregor MI, Luchsinger PC, Ball WC Jr. Pleural Effusions: The Diagnostic Separation of Transudates and Exudates. Annals of Internal Medicine. 1972;77(4):507\u201313. DOI: 10.7326\/0003-4819-77-4-507","DOI":"10.7326\/0003-4819-77-4-507"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Buoro S, Tombetti E, Ceriotti F, Simon C, Cugola D, Seghezzi M et al. What is the normal composition of pericardial fluid? Heart. 2021;107(19):1584\u201390. DOI: 10.1136\/heartjnl-2020-317966","DOI":"10.1136\/heartjnl-2020-317966"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"K\u00fc\u00e7\u00fck U, Gazi E, K\u0131r\u0131lmaz B. Roles of the Ratio of C-Reactive Protein to Serum and Pericardial Fluid Albumin Levels in Predicting in-Hospital Mortality in Patients Undergoing Pericardiocentesis. Archives of Current Medical Research. 2021;2(3):146\u201352","DOI":"10.47482\/acmr.2021.29"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Af\u015fin A, Aso\u011flu R, Kurto\u011flu E, Kaya H. Neutrophil to Lymphocyte Ratio as a Predictor of Left Ventricular Hypertrophy in Patients with Newly Diagnosed Hypertension. Journal of Hypertension and Management. 2019;5(2):1\u20139. DOI: 10.23937\/2474-3690\/1510042","DOI":"10.23937\/2474-3690\/1510042"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Shahim B, Redfors B, Lindman BR, Chen S, Dahlen T, Nazif T et al. Neutrophil\u2010to\u2010Lymphocyte Ratios in Patients Undergoing Aortic Valve Replacement: The PARTNER Trials and Registries. Journal of the American Heart Association. 2022;11(11):e024091. DOI: 10.1161\/JAHA.121.024091","DOI":"10.1161\/JAHA.121.024091"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Adamstein NH, MacFadyen JG, Rose LM, Glynn RJ, Dey AK, Libby P et al. The neutrophil\u2013lymphocyte ratio and incident atherosclerotic events: analyses from five contemporary randomized trials. European Heart Journal. 2021;42(9):896\u2013903. DOI: 10.1093\/eurheartj\/ehaa1034","DOI":"10.1093\/eurheartj\/ehaa1034"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Cho JH, Cho H-J, Lee H-Y, Ki Y-J, Jeon E-S, Hwang K-K et al. Neutrophil-Lymphocyte Ratio in Patients with Acute Heart Failure Predicts In-Hospital and Long-Term Mortality. Journal of Clinical Medicine. 2020;9(2):557. 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