{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:32:08Z","timestamp":1793640728584,"version":"4.5.1"},"reference-count":7,"publisher":null,"issue":"2","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>Currently, the diagnosis of amyloid cardiomyopathy (ACM) causes great difficulties both for practicing primary care physicians and specialists. One of the reasons is the variety of symptoms in patients with ACM. The most common ACM manifestations include heart failure with preserved left ventricular ejection fraction, hypertrophic phenotype of cardiomyopathy, thromboembolic complications, and valvular apparatus damage. Common valvular manifestations are mitral and tricuspid valve insufficiency and aortic stenosis (AS). Diagnosis is particularly difficult in patients with AS requiring differentiation between AS as a degenerative defect and AS of amyloid origin. According to the literature, in 4-16% of cases of older patients (\u226565 years), the genesis of AS is precisely the amyloid damage.<\/jats:p>","DOI":"10.18087\/cardio.2025.2.n2849","type":"journal-article","created":{"date-parts":[[2025,3,7]],"date-time":"2025-03-07T09:32:11Z","timestamp":1741339931000},"page":"69-76","source":"Crossref","is-referenced-by-count":0,"title":["Transthyretin Amyloid Cardiomyopathy as the Cause of Aortic Stenosis"],"prefix":"10.68900","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9432-5329","authenticated-orcid":true,"given":"M. V.","family":"Ezhikova","sequence":"first","affiliation":[{"name":"Chazov Russian Cardiology Research and Production Complex, Moscow"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0920-7417","authenticated-orcid":true,"given":"S. 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A.","family":"Saidova","sequence":"additional","affiliation":[{"name":"Chazov Russian Cardiology Research and Production Complex, Moscow"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9234-6129","authenticated-orcid":true,"given":"S. N.","family":"Tereshchenko","sequence":"additional","affiliation":[{"name":"Chazov Russian Cardiology Research and Production Complex, Moscow"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Savarese G, Becher PM, Lund LH, Seferovic P, Rosano GMC, Coats AJS. Global burden of heart failure: a comprehensive and updated review of epidemiology. Cardiovascular Research. 2023;118(17):3272\u201387. 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DOI: 10.1001\/jamacardio.2021.3070","DOI":"10.1001\/jamacardio.2021.3070"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Chen S, Pop A, Prasad Dasi L, George I. Lifetime Management for Aortic Stenosis: Strategy and Decision-Making in the Current Era. The Annals of Thoracic Surgery. 2025;119(2):296\u2013307. DOI: 10.1016\/j.athoracsur.2024.05.047","DOI":"10.1016\/j.athoracsur.2024.05.047"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Jaiswal V, Agrawal V, Khulbe Y, Hanif M, Huang H, Hameed M et al. Cardiac amyloidosis and aortic stenosis: a state-of-the-art review. European Heart Journal Open. 2023;3(6):oead106. DOI: 10.1093\/ehjopen\/oead106","DOI":"10.1093\/ehjopen\/oead106"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Brito D, Albrecht FC, De Arenaza DP, Bart N, Better N, Carvajal-Juarez I et al. World Heart Federation Consensus on Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM). Global Heart. 2023;18(1):59. 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