{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:31:14Z","timestamp":1793640674412,"version":"4.5.1"},"reference-count":16,"publisher":null,"issue":"1","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/cardio.elpub.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>\n                    <jats:italic>Aim:<\/jats:italic>\n                    To assess central arterial pressure (CAP) in young overweight women accounting for their arterial hypertension (AH) phenotype derived from 24-hour ambulatory blood pressure monitoring (ABPM) data.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Material and methods<\/jats:italic>\n                    : The study included 145 women aged 18 to 35 years with excess (n=104) and normal (n=41) body weight (BW). All subjects underwent office blood pressure (BP) measurement and ABPM with an oscillometric sensor using a BPLab Vasotens device (Petr Telegin LLC, Nizhny Novgorod) with an additional diagnostic option for determining CAP. Group 1 consisted of normotensive women with normal body weight (n=41). Among women with overweight and obesity, the following comparison groups were formed based on ABPM results: Group 2, sustained normotension (n=30), Group 3, \"white coat\" hypertension (WCH, n=10), Group 4, masked hypertension (n=32), and Group 5, sustained AH (n=32). CAP was evaluated in these groups, including Group 1 of age-matched normotensives with normal body weight. This allowed identifying the following conditions: sustained combined normotension; isolated peripheral hypertension; isolated central hypertension (CH); combined CH with office AH; combined CH with ambulatory AH; and sustained combined hypertension.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Results<\/jats:italic>\n                    : CH was detected in almost 10% of Group 1 normotensive women with normal body weight. In normotensive women but with overweight and obesity (Group 2), CH was found in almost half of the examined subjects. Elevated CAP incidence in overweight and obese young women varied by ABPM phenotype of AH appearing in practically a third of WCH cases, and nearly all cases of masked or sustained AH. In our sample, CH was detected in 2 out of 3 overweight women. Analysis of the prevalence of AH hemodynamic variants showed that among the examined women with and without overweight, women with isolated CH (comprising 13% of the cohort) were predominantly overweight (78%). Correlation analysis indicated that increased BMI and waist circumference significantly influenced intra-aortic pressure, linking metabolic risk factors with central and peripheral hemodynamics\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:italic>Conclusion<\/jats:italic>\n                    : For young women with overweight or obesity, preventive strategies should include, in addition to measuring office and ambulatory BP, wider implementation of CAP assessment, even if they are initially normotensive, due to their high risk of elevated aortic pressure, despite their young age. Furthermore, CH may affect roughly 10% of normotensive, normal-weight peers. Consequently, this prevalence should be addressed during management of this patient group within primary healthcare settings, including health centers, student polyclinics, and prevention departments (offices).\n                  <\/jats:p>","DOI":"10.18087\/cardio.2026.1.n2972","type":"journal-article","created":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T14:56:45Z","timestamp":1770821805000},"page":"24-30","source":"Crossref","is-referenced-by-count":0,"title":["Aortic Pressure in Different Phenotypes of Hypertension in Young Women, Taking Into Account Their Body Weight"],"prefix":"10.68900","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9579-252X","authenticated-orcid":true,"given":"M. E.","family":"Evsevyeva","sequence":"first","affiliation":[{"name":"Stavropol State Medical University, Stavropol"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8269-6434","authenticated-orcid":true,"given":"I. I.","family":"Kolomoitseva","sequence":"additional","affiliation":[{"name":"Stavropol State Medical University, Stavropol"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5273-5194","authenticated-orcid":true,"given":"O. V.","family":"Sergeeva","sequence":"additional","affiliation":[{"name":"Stavropol State Medical University, Stavropol"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3831-2109","authenticated-orcid":true,"given":"I. N.","family":"Gachkova","sequence":"additional","affiliation":[{"name":"Stavropol State Medical University, Stavropol"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4149-816X","authenticated-orcid":true,"given":"O. V.","family":"Ovchinnikova","sequence":"additional","affiliation":[{"name":"Krasnodar Territorial Clinical Hospital #2, Krasnodar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":null,"published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Murray CJL, Aravkin AY, Zheng P, Abbafati C, Abbas KM, Abbasi-Kangevari M et al. Global burden of 87 risk factors in 204 countries and territories, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet. 2020;396(10258):1223\u201349. DOI: 10.1016\/S0140-6736(20)30752-2","DOI":"10.1016\/S0140-6736(20)30752-2"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Huang Q-F, Aparicio LS, Thijs L, Wei F-F, Melgarejo JD, Cheng Y-B et al. Cardiovascular End Points and Mortality Are Not Closer Associated With Central Than Peripheral Pulsatile Blood Pressure Components. Hypertension. 2020;76(2):350\u20138. DOI: 10.1161\/HYPERTENSIONAHA.120.14787","DOI":"10.1161\/HYPERTENSIONAHA.120.14787"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"McEniery CM, Cockcroft JR, Roman MJ, Franklin SS, Wilkinson IB. Central blood pressure: current evidence and clinical importance. European Heart Journal. 2014;35(26):1719\u201325. DOI: 10.1093\/eurheartj\/eht565","DOI":"10.1093\/eurheartj\/eht565"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Milyagin V.A., Kovaleva O.A., Punin D.A. Central arterial pressure measurement as a promising method for identifying the initial stage of arterial hypertension. Therapy. 2021;2(44):39\u201349. DOI: 10.18565\/therapy.2021.2.39-49","DOI":"10.18565\/therapy.2021.2.39-49"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Kollias A, Lagou S, Zeniodi ME, Boubouchairopoulou N, Stergiou GS. Association of Central Versus Brachial Blood Pressure With Target-Organ Damage: Systematic Review and Meta-Analysis. Hypertension. 2016;67(1):183\u201390. DOI: 10.1161\/HYPERTENSIONAHA.115.06066","DOI":"10.1161\/HYPERTENSIONAHA.115.06066"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Aparicio LS, Huang Q-F, Melgarejo JD, Wei D-M, Thijs L, Wei F-F et al. The International Database of Central Arterial Properties for Risk Stratification: Research Objectives and Baseline Characteristics of Participants. American Journal of Hypertension. 2022;35(1):54\u201364. DOI: 10.1093\/ajh\/hpab139","DOI":"10.1093\/ajh\/hpab139"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Cheng Y-B, Thijs L, Aparicio LS, Huang Q-F, Wei F-F, Yu Y-L et al. Risk Stratification by Cross-Classification of Central and Brachial Systolic Blood Pressure. Hypertension. 2022;79(5):1101\u201311. DOI: 10.1161\/HYPERTENSIONAHA.121.18773","DOI":"10.1161\/HYPERTENSIONAHA.121.18773"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Posokhov I.N., Maroz-Vadalazhskaya N.N. Oscillometric method: what is it and is it suitable for measuring blood pressure in all patients? Cardiovascular Therapy and Prevention. 2024;23(9):131\u201342. DOI: 10.15829\/1728-8800-2024-4075","DOI":"10.15829\/1728-8800-2024-4075"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Kobalava Zh.D., Konradi A.O., Nedogoda S.V., Shlyakhto E.V., Arutyunov G.P., Baranova E.I. et al. 2024 Clinical practice guidelines for Hypertension in adults. Russian Journal of Cardiology. 2024;29(9):230\u2013 329. DOI: 10.15829\/1560-4071-2024-6117","DOI":"10.15829\/1560-4071-2024-6117"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Shalnova S.A., Deev A.D., Balanova Yu.A., Kapustina A.V., Imaeva A.E., Muromtseva G.A. et al. Twenty years trends of obesity and arterial hypertension and their association in Russia. Cardiovascular Therapy and Prevention. 2017;16(4):4\u201310. DOI: 10.15829\/1728-8800-2017-4-4-10","DOI":"10.15829\/1728-8800-2017-4-4-10"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Murkamilov I.T., Fomin V.V., Sabirov I.S., Yusupov F.A., Aidarov Z.A. Central aortic pressure, precerebral artery status, and renal function in individuals at high cardiovascular risk. Russian Journal of Preventive Medicine. 2023;26(6):91\u20139. DOI: 10.17116\/profmed20232606191","DOI":"10.17116\/profmed20232606191"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Roman MJ, Okin PM, Kizer JR, Lee ET, Howard BV, Devereux RB. Relations of central and brachial blood pressure to left ventricular hypertrophy and geometry: the Strong Heart Study: Journal of Hypertension. 2010;28(2):384\u20138. DOI: 10.1097\/HJH.0b013e328333d228","DOI":"10.1097\/HJH.0b013e328333d228"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"\u00d6stergren J, Poulter NR, Sever PS, Dahl\u00f6f B, Wedel H, Beevers G et al. The Anglo-Scandinavian Cardiac Outcomes Trial: blood pressure-lowering limb: effects in patients with type II diabetes. Journal of Hypertension. 2008;26(11):2103\u201311. DOI: 10.1097\/HJH.0b013e328310e0d9","DOI":"10.1097\/HJH.0b013e328310e0d9"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Williams B, Lacy PS, Thom SM, Cruickshank K, Stanton A, Collier D et al. Differential Impact of Blood Pressure \u2013 Lowering Drugs on Central Aortic Pressure and Clinical Outcomes: Principal Results of the Conduit Artery Function Evaluation (CAFE) Study. Circulation. 2006;113(9):1213\u201325. DOI: 10.1161\/CIRCULATIONAHA.105.595496","DOI":"10.1161\/CIRCULATIONAHA.105.595496"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Boggia J, Thijs L, Hansen TW, Li Y, Kikuya M, Bj\u00f6rklund-Bodeg\u00e5rd K et al. Ambulatory Blood Pressure Monitoring in 9357 Subjects From 11 Populations Highlights Missed Opportunities for Cardiovascular Prevention in Women. Hypertension. 2011;57(3):397\u2013405. DOI: 10.1161\/HYPERTENSIONAHA.110.156828","DOI":"10.1161\/HYPERTENSIONAHA.110.156828"},{"key":"ref16","doi-asserted-by":"crossref","unstructured":"Evsevieva M.E., Sergeeva O.V., Rusidi A.V., Rostovtseva M.V., Kudryavtseva V.D., Kryuchkov M.S. et al. Youth obesity paradox from the perspective of vascular stiffness, blood pressure and metabolic status. Russian Journal of Cardiology. 2024;29(5):38\u201345. DOI: 10.15829\/1560-4071-2024-5739","DOI":"10.15829\/1560-4071-2024-5739"}],"container-title":["Kardiologiia"],"original-title":[],"link":[{"URL":"https:\/\/cardio.elpub.ru\/jour\/article\/viewFile\/2972\/1969","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:16:48Z","timestamp":1793639808000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardio.elpub.ru\/jour\/article\/view\/2972"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,11]]},"references-count":16,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,2,11]]}},"URL":"https:\/\/doi.org\/10.18087\/cardio.2026.1.n2972","relation":{},"ISSN":["2412-5660","0022-9040"],"issn-type":[{"value":"2412-5660","type":"electronic"},{"value":"0022-9040","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2,11]]}}}