{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T16:40:03Z","timestamp":1746376803812,"version":"3.40.4"},"reference-count":16,"publisher":"APO Society of Specialists in Heart Failure","issue":"3S","license":[{"start":{"date-parts":[[2019,4,13]],"date-time":"2019-04-13T00:00:00Z","timestamp":1555113600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/lib.ossn.ru\/jour\/about\/editorialPolicies#openAccessPolicy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Kardiologiia"],"abstract":"<jats:p>The aim of the study was to investigate the prevalence of angina pectoris (AP) according to the standardized epidemiological questionnaire of Rose in the population of 25\u201345 years of Novosibirsk and to identify its association with some lipid and non-lipid risk factors for coronary heart disease (CHD). Material and methods. Cross-sectional survey of the population aged 25\u201345 in Novosibirsk was carried out. The study included 1439 people (656 men and 783 women). Within the framework of the complex survey program, the\u00a0standardized epidemiological questionnaire of Rose (WHO, 1984) was used. Blood levels of total cholesterol (total C), triglycerides (TG), low and high density lipoprotein cholesterol (LDL\u2013C, HDL\u2013C) were determinate by biochemical methods. Results. For all lipid indicators, significant differences were found between men and women. The levels of total C, TG and LDL\u2013C were significantly higher, and the level of HDL\u2013C was lower in men, than in women. According to the Rose questionnaire, out of 1439 people included in the study, 12 patients (0.8%) had AP (75% women). In persons with AP, blood levels of TG were 1.8 times higher, and the levels of\u00a0HDL\u2013C in blood was 1.2 times lower compared to persons without AP. Univariate analysis of associations of AP with CHD risk factors showed that the chance of developing angina pectoris in the population of 25\u201345 years was significantly increased in individuals with high blood TG levels (OR 3,515, DI 1,106\u201311,168, p = 0.039) and low HDL\u2013C (OR 1,203, DI 1,054\u20131,372, p = 0.006). A natural, although statistically not significant (OR 3,165, p=0,055, due to the small number of groups with AP) increasing in the\u00a0chance of\u00a0developing AP in hypertension was detected. Conclusion. In the young population of 25\u201345 years in Novosibirsk, elevated blood levels of TG, reduced levels of HDL\u2013C, and hypertension were associated with AP, according to Rosecardiological questionnaire, which underlines the importance of conducting screening surveys of the young population to improve effective prevention and treatment of diseases.<\/jats:p>","DOI":"10.18087\/cardio.2600","type":"journal-article","created":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T09:07:47Z","timestamp":1555405667000},"page":"30-35","source":"Crossref","is-referenced-by-count":5,"title":["Blood lipids and angina pectoris (by epidemiological cardiological Rose questionnaire) in the population of 25-45 years of Novosibirsk"],"prefix":"10.18087","volume":"59","author":[{"given":"Yu. I.","family":"Ragino","sequence":"first","affiliation":[{"name":"Research Institute of Internal and Preventive Medicine \u2013 Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM \u2013 Branch of IC G SB RAS); B. Bogatkov Str., 175\/1, Novosibirsk, 630089, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. V.","family":"Shcherbakova","sequence":"additional","affiliation":[{"name":"Research Institute of Internal and Preventive Medicine \u2013 Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM \u2013 Branch of IC G SB RAS); B. Bogatkov Str., 175\/1, Novosibirsk, 630089, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. V.","family":"Denisova","sequence":"additional","affiliation":[{"name":"Research Institute of Internal and Preventive Medicine \u2013 Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM \u2013 Branch of IC G SB RAS); B. Bogatkov Str., 175\/1, Novosibirsk, 630089, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. A.","family":"Kuzminykh","sequence":"additional","affiliation":[{"name":"Research Institute of Internal and Preventive Medicine \u2013 Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM \u2013 Branch of IC G SB RAS); B. Bogatkov Str., 175\/1, Novosibirsk, 630089, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. P.","family":"Yachmeneva","sequence":"additional","affiliation":[{"name":"Research Institute of Internal and Preventive Medicine \u2013 Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM \u2013 Branch of IC G SB RAS); B. Bogatkov Str., 175\/1, Novosibirsk, 630089, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. I.","family":"Voevoda","sequence":"additional","affiliation":[{"name":"Research Institute of Internal and Preventive Medicine \u2013 Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences (IIPM \u2013 Branch of IC G SB RAS); B. Bogatkov Str., 175\/1, Novosibirsk, 630089, Russian Federation"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7442","published-online":{"date-parts":[[2019,4,13]]},"reference":[{"key":"#cr-split#-ref1.2","doi-asserted-by":"crossref","unstructured":"10.7326\/M16-2052","DOI":"10.7326\/M16-2052"},{"key":"#cr-split#-ref2.2","doi-asserted-by":"crossref","unstructured":"10.1016\/j.atherosclerosis.2008.07.002","DOI":"10.1016\/j.atherosclerosis.2008.07.002"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Yachmeneva M. P., Ragino Yu. I. The role of hyperlipidemia and hyperglycemia in the development of coronary heart disease in young population. Ateroskleroz. 2018;14(1):38\u201342. [Russian: Yachmeneva M. P., Ragino Yu. I. Rol' giperlipidemii i giperglikemii v razvitii ishemicheskoi bolezni serdtsa v molodoi populyatsii. Ateroskleroz. 2018;14(1):38-42]. 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DOI: 10.1590\/1980-5497201500060011","DOI":"10.1590\/1980-5497201500060011"}],"container-title":["Kardiologiia"],"original-title":[],"link":[{"URL":"https:\/\/lib.ossn.ru\/jour\/article\/viewFile\/576\/394","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,4]],"date-time":"2025-05-04T16:02:27Z","timestamp":1746374547000},"score":1,"resource":{"primary":{"URL":"https:\/\/cardio.elpub.ru\/jour\/article\/view\/576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,13]]},"references-count":16,"journal-issue":{"issue":"3S","published-online":{"date-parts":[[2019,4,13]]}},"URL":"https:\/\/doi.org\/10.18087\/cardio.2600","relation":{},"ISSN":["2412-5660","0022-9040"],"issn-type":[{"type":"electronic","value":"2412-5660"},{"type":"print","value":"0022-9040"}],"subject":[],"published":{"date-parts":[[2019,4,13]]}}}