{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T07:48:27Z","timestamp":1791186507003,"version":"4.1.0"},"reference-count":27,"publisher":"Institute of Biochemistry","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BIOMED KHIM"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:p>Parameters reflecting oxidative stress (OS) have been studied in 37 patients with alcoholic liver disease (ALD) during admission to the hospital and 2 weeks after the beginning of therapy. The patients were divided into 3 groups: alcoholic hepatitis (AH), alcoholic cirrhosis with hepatic insufficiency (the group C with Child-Paquet) and terminal stage patients (they subsequently died). All patients were characterized by a significant increase in plasma products of lipid peroxidation (conjugated diene and malondialdehyde) and decrease of the ceruloplasmin level. The coefficient K OS significantly exceeded normal values both on admission and after the 2-week course of traditional treatment. This suggests an important role of the OS with ALD.<\/jats:p>","DOI":"10.18097\/pbmc20135904452","type":"journal-article","created":{"date-parts":[[2015,4,24]],"date-time":"2015-04-24T12:34:12Z","timestamp":1429878852000},"page":"452-458","source":"Crossref","is-referenced-by-count":11,"title":["Oxidative stress in the of alcoholic liver disease"],"prefix":"10.18097","volume":"59","author":[{"given":"L.F.","family":"Panchenko","sequence":"first","affiliation":[{"name":"Institute of General Pathology and Pathophysiology of Russian Academy of Medical Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.V.","family":"Davydov","sequence":"additional","affiliation":[{"name":"National Scientific Center of Drug Addiction"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.N.","family":"Terebilina","sequence":"additional","affiliation":[{"name":"National Scientific Center of Drug Addiction"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.Yu.","family":"Baronets","sequence":"additional","affiliation":[{"name":"National Scientific Center of Drug Addiction"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.S.","family":"Zhuravleva","sequence":"additional","affiliation":[{"name":"Russian University of Peoples Friendship"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7443","published-online":{"date-parts":[[2013]]},"reference":[{"key":"ref1","unstructured":"Men'shhikova E.B., Lankin V.Z., Zenkov N.K., Bondar' I.\u0410., Krugovykh N.F., Trufakin V.\u0410. (2006) Okislitel'nyj stress. Prooksidanty i antioksidanty. \u201cSlovo\u201d, M."},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"Caro A.A., Cererbum A.I. (2004) Ann. Rev. Pharmacol. Toxicol., 44, 27-42.","DOI":"10.1146\/annurev.pharmtox.44.101802.121704"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Albano E. (2008) Mol. Asp. Med., 29, 9-16.","DOI":"10.1016\/j.mam.2007.09.004"},{"key":"ref4","unstructured":"Kuznetsov E.E., Gorokhova V.G., Gorokhov \u0410.G., Sergeeva \u0410.S., Kuril'skaya T.E., Pivovarov Yu.I., Runovich \u0410.\u0410. (2007) Byull. VSNTS SO R\u0410MN, 50(4), 170-180."},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Choi D.W., Leninger-Muller B., Wellman M. et al. (2004) J. Toxicol. Environ. Health A., 67, 2061-2071.","DOI":"10.1080\/15287390490514895"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Albano E. (2006) Proc. Nutr. Soc., 65, 278-290.","DOI":"10.1079\/PNS2006496"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Loguercio C. (2003) Free Rad. Biol. Med., 34(1), 1-10.","DOI":"10.1016\/S0891-5849(02)01167-X"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Arosio P., Levi S. (2002) Free Rad. Biol. Med., 33 (4), 457-463.","DOI":"10.1016\/S0891-5849(02)00842-0"},{"key":"ref9","unstructured":"Rao R.K., Seth A., Sheth P. (2004) Am. J. Physiol. 286, G881-G884."},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Hines I.N., Wheeler M.D. (2004) Am. J. Physiol. 287, G310-G314.","DOI":"10.1152\/ajpcell.00534.2003"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Pacher P., Beckman J.S., Liaudet L. (2007) Physiol. Rev., 87 (1), 315-424.","DOI":"10.1152\/physrev.00029.2006"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Reed D.J. (2004) Drug Metab. Rev., 36 (3-4), 569-582.","DOI":"10.1081\/DMR-200033449"},{"key":"ref13","unstructured":"Feldman M., Friedman L.S., Sleisenger M.H. (2002) Gastrointestinal and liver disease. Saunders, 1375-1391."},{"key":"ref14","unstructured":"Kono H., BradfordB.U., Yin M. (1999) Am. J. Physiol., 277, G1259-G1267."},{"key":"ref15","unstructured":"Chesnokova N.P., Ponukalina E.V., Bizenkova M.N. (2006) Sovremennye naukoyomkie tekhnologii, \u21166, 21-26."},{"key":"ref16","unstructured":"Panchenko L.F., Pirozhkov S.V., Dudko T.N. Baronets V.YU., \u0410lyab'eva T.N., Peregud D.I. (2008) Vopr. narkologii, \u21166, 42-47."},{"key":"ref17","unstructured":"Pirozhkov S.V., Panchenko L.F., Dudko T.N.,.Baronets V.YU. \u0410lyab'eva T.\u0410., Peregud D.I. (2005) Narkologiya, \u21166, 32-37."},{"key":"ref18","unstructured":"Bronovets I.N., Goncharik I.I., Demidchik E.P., Sakovich M.N. (1997) Spravochnik po gastroehnterologii. Minsk."},{"key":"ref19","unstructured":"Gavrilov V.B., Gavrilova A.R., Mazhul' L.M. (1987) Voprosy Meditsinskoi Khimii,  33(1), 118-122"},{"key":"ref20","unstructured":"Kagan V.E., Orlov V.N., Prilipko L.I. (1986) Problema analiza ehndogennykh produktov perekisnogo okisleniya lipidov. Nauka, M."},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"DugganD.E. (1959) Arch. Biochem. Biophis. 84(1), 116-122.","DOI":"10.1016\/0003-9861(59)90559-4"},{"key":"ref22","unstructured":"Ravin H.A. (1961) J. Lab. Clin. Med., 58(1), 161-168."},{"key":"ref23","unstructured":"Davydov B.V., Polumiskov V.Yu., Golikov P.P., Golikov \u0410.P. (1991) V kn.: Klinicheskaya laboratornaya diagnostika. Tez. dokl. 4 Vsesoyuznogo s'ezda spetsialistov po klinicheskoj laboratornoj diagnostike. M., 48-49."},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"Jeffrey G.P., Muller D.P.R., Burroughs A.K., Matthews S., Kemp C., Epstein O., Metcalfe T.A. et al. (1987) J. Hepatol., 4, 307-117.","DOI":"10.1016\/S0168-8278(87)80539-1"},{"key":"ref25","unstructured":"Bilibin D.P., Dvornikov V.E. (1990) Patofiziologiya alkogol'noj bolezni i narkomanij. Universitet Druzhby narodov, M."},{"key":"ref26","unstructured":"Golikov P.P., Davydov B.V., Matveev S.B. (1987) Voprosy Meditsinskoi Khimii, 33(1), 47-50"},{"key":"ref27","unstructured":"Vashhenko V.I., Vashhenko T.N. (2006) Psikhofarmakol. biol. narkol., 6(3), 1245-1269."}],"container-title":["Biomeditsinskaya Khimiya"],"original-title":[],"language":"ru","deposited":{"date-parts":[[2019,9,16]],"date-time":"2019-09-16T15:50:47Z","timestamp":1568649047000},"score":1,"resource":{"primary":{"URL":"http:\/\/pbmc.ibmc.msk.ru\/en\/article-en\/PBMC-2013-59-4-452"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":27,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013]]},"published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.18097\/pbmc20135904452","relation":{},"ISSN":["2310-6905","2310-6972"],"issn-type":[{"value":"2310-6905","type":"electronic"},{"value":"2310-6972","type":"print"}],"subject":[],"published":{"date-parts":[[2013]]}}}