{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T21:41:27Z","timestamp":1648935687173},"reference-count":35,"publisher":"Institute of Biochemistry","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BIOMED KHIM"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:p>Objective was to analyze metabolic pathways based on a study of the metabolomic profile of pregnant women  with intrauterine growth restriction. The metabolic profile of pregnant women with fetal growth restriction has been  analyzed using liquid chromatography-mass spectrometry. At the second stage pathways were identified using SMPDB  and MetaboAnalyst databases to clarify the relationship between metabolites. Biological networks allow to determine  the effect of proteins on the metabolic pathways involved in pathogenesis of IUGR and determine the epigenetic  mechanisms of its formation.<\/jats:p>","DOI":"10.18097\/pbmc20206602174","type":"journal-article","created":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T14:54:24Z","timestamp":1589468064000},"page":"174-180","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of metabolic pathways in intrauterine growth restriction"],"prefix":"10.18097","volume":"66","author":[{"given":"N.E.","family":"Kan","sequence":"first","affiliation":[{"name":"Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Z.V.","family":"Khachatryan","sequence":"additional","affiliation":[{"name":"Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.V.","family":"Chagovets","sequence":"additional","affiliation":[{"name":"Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.L.","family":"Starodubtseva","sequence":"additional","affiliation":[{"name":"Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.Yu.","family":"Amiraslanov","sequence":"additional","affiliation":[{"name":"Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.L.","family":"Tyutyunnik","sequence":"additional","affiliation":[{"name":"Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.A.","family":"Lomova","sequence":"additional","affiliation":[{"name":"Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.E.","family":"Frankevich","sequence":"additional","affiliation":[{"name":"Academician V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7443","published-online":{"date-parts":[[2020]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Malyshkina A.I., Boyko E.L., Sotnikova N.Yu., Panova I.A., Fetisova I.N., Voronin D.N., Mileeva P.L. (2019) Akusherstvo i Ginekologiya, 6, 40-46.","DOI":"10.18565\/aig.2019.6.40-46"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Skripnichenko Yu.P., Pyataeva S.V., Volodina M.A., Tsvirkun D.V., Baranov I.I., Vyssokikh M.Yu., Kuzmich I.N. (2017) Akusherstvo i Ginekologiya, 8, 60-66.","DOI":"10.18565\/aig.2017.8.60-6"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"Lee A.C., Kozuki N., Cousens S., Stevens G.A., Blencowe H., Silveira M.F. et al. (2017) BMJ, 358, j3677.","DOI":"10.1136\/bmj.j3677"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"Lager S., Powell T.L. (2012) J. Pregnancy, 2012, 179827.","DOI":"10.1155\/2012\/179827"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"Vaughan O.R., Rosario F.J., Powell T.L., Jansson T. (2017) Prog. Mol. Biol. Transl. Sci., 145, 217-251.","DOI":"10.1016\/bs.pmbts.2016.12.008"},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"Lewis R.M., Brooks S., Crocker I.P., Glazier J., Hanson M.A., Johnstone E.D. et al. (2013) Placenta, 34, S46-S51.","DOI":"10.1016\/j.placenta.2012.10.010"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"Avagliano L., Gar\u00f3 C., Marconi A.M. (2012) J. Pregnancy, 2012, 972562.","DOI":"10.1155\/2012\/972562"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"Wu G., Bazer F.W., Dai Z., Li D., Wang J., Wu Z. (2014) Annu. Rev. Anim. Biosci., 2014(2), 387-417.","DOI":"10.1146\/annurev-animal-022513-114113"},{"key":"ref9","unstructured":"Kan N.E., Khachatryan Z.V., Amiraslanov E.Yu., Chagovets V.V., Tyutyunnik V.L., Lomova N.A., Starodubtseva N.L., Kitsilovskaya N.A., Baranov I.I., Frankevich V.E. (2019) Akusherstvo i Ginekologiya, 12, 59-65."},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"Dess\u00ec A., Atzori L., Noto A., Visser G.H., Gazzolo D., Zanardo V. et al. (2011) J. Matern. Fetal Neonatal. Med., 24(Suppl 2), 35-39.","DOI":"10.3109\/14767058.2011.605868"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"Bahado-Singh R.O., Yilmaz A., Bisgin H., Turkoglu O., Kumar P., Sherman E. et al. (2019) PLoS One, 14(4), e0214121.","DOI":"10.1371\/journal.pone.0214121"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"Liu J., Chen X.X., Li X.W., Fu W., Zhang W.Q. (2016) Medicine (Baltimore), 95(17), e3564.","DOI":"10.1097\/MD.0000000000003564"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"Camprub\u00ed Camprub\u00ed M., Balada Caball\u00e9 R., Ortega Cano J.A., Ortega de la Torre M.L., Duran Fern\u00e1ndez-Feijoo C., Girabent-Farr\u00e9s M. et al. (2017) Brain Behav., 7(3), e00631.","DOI":"10.1002\/brb3.631"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"Chen J., Chen P., Bo T., Luo K. (2016) Pediatrics, 137(4), e20153868.","DOI":"10.1542\/peds.2015-3868"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"Vollmer B., Edmonds C.J. (2019) Front. Endocrinol. (Lausanne), 10, 186.","DOI":"10.3389\/fendo.2019.00186"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"Kostandy B.B. (2012) Neurol Sci., 33, 223-237.","DOI":"10.1007\/s10072-011-0828-5"},{"key":"ref17","doi-asserted-by":"publisher","unstructured":"Shen J. (2013) Front Neuroenergetics, 5, 1.","DOI":"10.3389\/fnene.2013.00001"},{"key":"ref18","doi-asserted-by":"publisher","unstructured":"Rodriguez M., Sabate M., Rodriguez-Sabate C., Morales I. (2013) Brain Res Bull., 93, 17-26.","DOI":"10.1016\/j.brainresbull.2012.09.018"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"Hackett J.T., Ueda T. (2015) Neurochem Res., 40(12), 2443-2460.","DOI":"10.1007\/s11064-015-1622-1"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"Dhanasiri A.K., Fernandes J.M., Kiron V. (2012) Comp. Biochem. Physiol. B: Biochem. Mol. Biol., 163(3-4), 274-284.","DOI":"10.1016\/j.cbpb.2012.06.003"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"Sonnewald U., Schousboe A. (2016) Adv. Neurobiol., 13, 1-7.","DOI":"10.1007\/978-3-319-45096-4_1"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"Hertz L. (2013) Front. Endocrinol. (Lausanne), 4, 59.","DOI":"10.3389\/fendo.2013.00059"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"Wu G. (2009) Amino Acids, 37, 1-17.","DOI":"10.1007\/s00726-009-0269-0"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"Yamauchi K., Komatsu T., Kulkarni A.D., Ohmori Y., Minami H., Ushiyama Y., Nakayama M., Yamamoto S. (2002) Nutrition, 18, 329-333.","DOI":"10.1016\/S0899-9007(01)00788-2"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Blachier F., Boutry C., Bos C., Tome D. (2009) Am. J. Clin. Nutr., 90, 814S\u2013821S.","DOI":"10.3945\/ajcn.2009.27462S"},{"key":"ref26","doi-asserted-by":"publisher","unstructured":"Self J.T., Spencer T.E., Johnson G.A., Hu J., Bazer F.W., Wu G. (2004) Biol. Reprod., 70, 1444-1451.","DOI":"10.1095\/biolreprod.103.025486"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"Cercato M.C., Colettis N., Snitcofsky M., Aguirre A.I., Kornisiuk E.E., Baez M.V. et al. (2014) J. Physiol. (Paris), 108(4-6), 263-269.","DOI":"10.1016\/j.jphysparis.2014.08.001"},{"key":"ref28","doi-asserted-by":"publisher","unstructured":"Khan M.A., Houck D.R., Gross A.L., Zhang X.L., Cearley C., Madsen T.M. et al. (2018) Int. J. Neuropsychopharmacol., 21(3), 242-254.","DOI":"10.1093\/ijnp\/pyx096"},{"key":"ref29","doi-asserted-by":"publisher","unstructured":"Thorn S.R., Rozance P.J., Brown L.D., Hay W.W. Jr. (2011) Semin. Reprod. Med., 29(3), 225-236.","DOI":"10.1055\/s-0031-1275516"},{"key":"ref30","doi-asserted-by":"publisher","unstructured":"Zimmermann E., Gamborg M., Sorensen T.I., Baker J.L. (2015) Diabetes, 64(12), 4220-4225.","DOI":"10.2337\/db15-0494"},{"key":"ref31","doi-asserted-by":"publisher","unstructured":"Limesand S.W., Rozance P.J. (2017) J. Physiol., 595(15), 5103-5113.","DOI":"10.1113\/JP273324"},{"key":"ref32","unstructured":"Luo K., Chen P., Xie Z., Li W., Li S., He M. (2014) Zhong Nan Da Xue Xue Bao Yi Xue Ban, 39(4), 395-400."},{"key":"ref33","doi-asserted-by":"publisher","unstructured":"Birsoy K., Wang T., Chen W.W., Freinkman E., Abu-Remaileh M., Sabatini D.M. (2015) Cell, 162(3), 540-551.","DOI":"10.1016\/j.cell.2015.07.016"},{"key":"ref34","doi-asserted-by":"publisher","unstructured":"Lane A.N., Fan T.W. (2015) Nucl. Acids Res., 43(4), 2466-2485.","DOI":"10.1093\/nar\/gkv047"},{"key":"ref35","doi-asserted-by":"publisher","unstructured":"Zhang H., Su W., Ying Z., Chen Y. et al. (2018) Eur. J. Nutr., 57(1), 327-338.","DOI":"10.1007\/s00394-016-1322-x"}],"container-title":["Biomeditsinskaya Khimiya"],"original-title":[],"language":"ru","deposited":{"date-parts":[[2020,5,14]],"date-time":"2020-05-14T14:55:04Z","timestamp":1589468104000},"score":1,"resource":{"primary":{"URL":"http:\/\/pbmc.ibmc.msk.ru\/en\/article-en\/PBMC-2020-66-2-174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020]]},"references-count":35,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2020]]},"published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.18097\/pbmc20206602174","relation":{},"ISSN":["2310-6905","2310-6972"],"issn-type":[{"value":"2310-6905","type":"electronic"},{"value":"2310-6972","type":"print"}],"subject":[],"published":{"date-parts":[[2020]]}}}