{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:04:12Z","timestamp":1794323052952,"version":"4.9.0"},"reference-count":0,"publisher":"European Society of Medicine","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MRAJ"],"abstract":"<jats:p>Background: Snakebite is a preventable yet often-neglected public health hazard with high chronic disability and mortality, mainly faced by rural communities in the tropics\/subtropics. Endocrinological disorders following snakebite (especially Russell's viper in India) are notably underrecognized and can lead to remarkable morbidity, poor quality of life, and cardiovascular mortality. Anterior pituitary insufficiency has been the most common ailment following Russell's viper envenomation amid those endocrinological dysfunctions. On the contrary, the posterior pituitary and nearby hypothalamus mostly remain unharmed, so central diabetes insipidus is extremely rare following a viperid snakebite envenomation. Case Presentation: The authors present a patient developing panhypopituitarism with evident spontaneous central diabetes insipidus 29 years after Russell's viper envenomation. Relevant investigations ruled out other possible etiologies, and he responded well to hormonal replacement therapy. Conclusions: Panhypopituitarism with concurrent central diabetes insipidus may occur following snakebite (especially in Russell's viper envenomation). Early recognition and proper management of these complications are quintessential to preventing further misdiagnosis, under-recognition, morbidity, impaired quality of life, and mortality.<\/jats:p>","DOI":"10.18103\/mra.v10i10.3195","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T06:03:48Z","timestamp":1667369028000},"source":"Crossref","is-referenced-by-count":4,"title":["Panhypopituitarism and Central Diabetes Insipidus Almost Three Decades After Russell's Viper Envenomation: A Remarkable Case Report and Literature Review"],"prefix":"10.18103","volume":"10","author":[{"given":"Ritwik","family":"Ghosh","sequence":"first","affiliation":[{"name":"Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mois\u00e9s","family":"Le\u00f3n-Ruiz","sequence":"additional","affiliation":[{"name":"Section of Clinical Neurophysiology, Department of Neurology, University Hospital \"La Paz,\" Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipayan","family":"Roy","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India; Indian Institute of Technology (IIT), Madras, Tamil Nadu, India; School of Humanities, Indira Gandhi National Open University, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sona Singh","family":"Sardar","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srijit","family":"Bandyopadhyay","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunal","family":"Bole","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Burdwan Medical College, and Hospital, Burdwan, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souvik","family":"Dubey","sequence":"additional","affiliation":[{"name":"Department of Neuromedicine, Bangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research & SSKM Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juli\u00e1n","family":"Benito-Le\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Neurology, University Hospital \"12 de Octubre\", Madrid, Spain; Centro de Investigaci\u00f3n Biom\u00e9dica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Medicine, Complutense University, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7483","published-online":{"date-parts":[[2022,10,31]]},"container-title":["Medical Research Archives"],"original-title":[],"link":[{"URL":"https:\/\/esmed.org\/MRA\/mra\/article\/download\/3195\/193546383","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esmed.org\/MRA\/mra\/article\/download\/3195\/193546383","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:14:03Z","timestamp":1792224843000},"score":1,"resource":{"primary":{"URL":"https:\/\/esmed.org\/MRA\/mra\/article\/view\/3195"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,31]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,10,31]]}},"URL":"https:\/\/doi.org\/10.18103\/mra.v10i10.3195","relation":{},"ISSN":["2375-1924","2375-1916"],"issn-type":[{"value":"2375-1924","type":"electronic"},{"value":"2375-1916","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10,31]]}}}