{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T03:46:04Z","timestamp":1780717564948,"version":"3.54.1"},"reference-count":0,"publisher":"Esmon Publicidad, SA","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Esp Sanid Penit"],"abstract":"<jats:p>Objectives: Latent TB infection (LTBI) affects 25% of the world\u2019s population. As long as this reservoir exists, the elimination of TB will not be feasible. The Assembly of the World Health Organization adopted the \u201cGlobal End TB\u201d strategy for the elimination of TB in 2014. The objective of this review is to present strategies for risk groups that are candidates for the detection and treatment of LTBI. Material and method: There is sufficient evidence of screening in: immunocompromised people (HIV-infected, biological therapies, alternative renal therapy, organ transplantation), recent immigrants, inmates in prison, people injecting drugs and homeless people, and workers from at-risk settings. Tests to diagnose LTBI include tuberculin skin test (TST) and gamma release assay interferon (IGRA). There is no reference test and the choice of one or the other will depend on logistical considerations, such as avoiding injection (TST) or not needing a second visit (IGRA). Treatment of LTBI is based on the use of isoniazide and rifampicin in short period of 3 or 4 months, using associations of rifampicin and isoniazide or rifampicin alone. Discussion: Given the estimated high prevalence of LTBI, renewed efforts are required to reduce the number of people with LTBI that includes a registration and monitoring system to observer progress, increased testing, and the use of short treatment guidelines.<\/jats:p>","DOI":"10.18176\/resp.00028","type":"journal-article","created":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T09:28:36Z","timestamp":1614245316000},"page":"28-36","source":"Crossref","is-referenced-by-count":11,"title":["Guidelines on controlling latent tuberculosis infection to support tuberculosis elimination"],"prefix":"10.18176","volume":"23","author":[{"given":"P","family":"Godoy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7491","published-online":{"date-parts":[[2021,2,24]]},"container-title":["Revista Espa\u00f1ola de Sanidad Penitenciaria"],"original-title":["English"],"deposited":{"date-parts":[[2021,2,25]],"date-time":"2021-02-25T09:28:37Z","timestamp":1614245317000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.sanipe.es\/OJS\/index.php\/RESP\/article\/view\/610\/1168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,24]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,2,24]]}},"URL":"https:\/\/doi.org\/10.18176\/resp.00028","relation":{},"ISSN":["2013-6463"],"issn-type":[{"value":"2013-6463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,24]]}}}