{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T14:59:02Z","timestamp":1788965942545,"version":"build-2803163510"},"reference-count":0,"publisher":"Press of International Journal of Ophthalmology (IJO Press)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Ophthalmol"],"published-print":{"date-parts":[[2023,10,18]]},"abstract":"<jats:p>AIM: To detect retinal microvascular variations in obstructive sleep apnea syndrome patients.\nMETHODS: This prospective, observational case-control study included healthy controls and patients with mild, moderate, and severe obstructive sleep apnea syndrome. Vascular parameters, foveal avascular area, and flow areas in macula-centered, 6.00\u00d76.00 mm2 scan size optical coherence tomography angiography images were compared.\nRESULTS: The control group had the highest whole image, parafoveal, and perifoveal vessel density among the groups in both superficial and the deep capillary plexus (all P&lt;0.05). Rapid eye movement sleep apnoea-hypopnoea index was reversely correlated with whole (Rho=-0.195, P=0.034), parafoveal (Rho=-0.242, P=0.008), perifoveal (Rho=-0.187, P=0.045) vessel density in the superficial capillary plexus, and whole (Rho=-0.186, P=0.046), parafoveal (Rho=-0.260, P=0.004), perifoveal (Rho=-0.189, P=0.043) vessel density in the deep capillary plexus, though the mean and non-rapid eye movement sleep apnoea-hypopnoea index related with only parafoveal vessel density in the superficial capillary plexus (Rho=-0.213, P=0.020; Rho=-0.191, P=0.038) and the deep capillary plexus (Rho=-0.254, P=0.005; Rho=-0.194, P=0.035).\nCONCLUSION: This study shows decreased vessel density and its reverse correlation with the apnoea-hypopnoea index in patients with obstructive sleep apnea syndrome.<\/jats:p>","DOI":"10.18240\/ijo.2023.10.17","type":"journal-article","created":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T02:21:08Z","timestamp":1695349268000},"page":"1670-1675","source":"Crossref","is-referenced-by-count":4,"title":["Effects of obstructive sleep apnea on retinal microvasculature"],"prefix":"10.18240","volume":"16","author":[{"name":"Ophthalmology Department, Mugla S&#x131;tk&#x131; Kocman University Training and Research Hospital, Mugla 48300, T&#xFC;rkiye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00fcjdat","family":"Karabulut","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinem","family":"Karabulut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Ophthalmology Department, Mugla S&#x131;tk&#x131; Kocman University Training and Research Hospital, Mugla 48300, T&#xFC;rkiye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aylin","family":"Karalezli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Ophthalmology Department, Mugla S&#x131;tk&#x131; Ko&#xE7;man University Faculty of Medicine, Mugla 48300, T&#xFC;rkiye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00fclnihal","family":"Kutlu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Neurology Department, Mugla S&#x131;tk&#x131; Ko&#xE7;man University Faculty of Medicine, Mugla 48300, T&#xFC;rkiye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7543","container-title":["International Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"http:\/\/ies.ijo.cn\/en_publish\/2023\/10\/20231017.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T02:21:38Z","timestamp":1695349298000},"score":1,"resource":{"primary":{"URL":"http:\/\/ies.ijo.cn\/gjyken\/ch\/reader\/view_abstract.aspx?file_no=20231017&flag=1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,18]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10,18]]}},"URL":"https:\/\/doi.org\/10.18240\/ijo.2023.10.17","relation":{},"ISSN":["2222-3959","2227-4898"],"issn-type":[{"value":"2222-3959","type":"print"},{"value":"2227-4898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,18]]}}}