{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T22:06:34Z","timestamp":1722981994058},"reference-count":0,"publisher":"Press of International Journal of Ophthalmology (IJO Press)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Ophthalmol"],"published-print":{"date-parts":[[2024,3,18]]},"abstract":"<jats:p>AIM: To determine the common causes and visual outcome after treatment among uveitis and scleritis patients.\nMETHODS: This is a retrospective cohort observational study. All consecutive clinical records of patients with newly diagnosed uveitis and scleritis over a 4-year period, from Jan. 1, 2017 to Dec. 31, 2020, were analysed. Data was collected at the presentation and included a follow-up period of one year.\nRESULTS: A total of 288 patients were recruited during the study period. Anterior uveitis was the most common anatomical diagnosis (50.0%) followed by panuveitis (25.0%), scleritis (13.5%), posterior uveitis (6.9%), and intermediate uveitis (4.5%). Viral Herpes was the most common cause of infectious cases, while Vogt-Koyanagi-Harada (VKH) disease and human leucocyte antigen (HLA) B27 spondyloarthropathy were the leading causes of identifiable non-infectious cases. Majority of patients presented with unilateral, non-granulomatous uveitis with an absence of hypopyon. Anatomical locations like posterior uveitis and panuveitis, and visual acuity worse than 3\/60 at presentation were the factors associated with poor visual outcomes (P&lt;0.05). About 60% of patients had an identifiable cause for the uveitis and scleritis, with nearly equal distribution of infectious (n=85, 29.5%) and non-infectious causes (n=84, 29.2%). About 14.5% of patients were clinically blind at 1y of follow-up. The most common complication in our uveitis patients was glaucoma (47.5%), followed by cystoid macula oedema (18.9%) and cataract (13.9%).\nCONCLUSION: Uveitis and scleritis are important causes of ocular morbidity. They are potentially blinding diseases which can have a good outcome if diagnosed and treated early.<\/jats:p>","DOI":"10.18240\/ijo.2024.03.14","type":"journal-article","created":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T08:50:50Z","timestamp":1709023850000},"page":"518-527","source":"Crossref","is-referenced-by-count":0,"title":["Treatment of uveitis and scleritis patients in Malaysia"],"prefix":"10.18240","volume":"17","author":[{"name":"Department of Ophthalmology, University Malaya Eye Research Centre (UMERC), Faculty of Medicine, Universiti Malaya, Kuala Lumpur 59100, Malaysia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sieng Teng","family":"Seow","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fei Yee","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Clinical Research Centre, Selayang Hospital, Ministry of Health Malaysia, Selangor 68100, Malaysia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooi Wah","family":"Lott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Ophthalmology, University Malaya Eye Research Centre (UMERC), Faculty of Medicine, Universiti Malaya, Kuala Lumpur 59100, Malaysia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sagili Chandrasekhara","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Department of Ophthalmology, Faculty of Medicine and Defence Health, National Defence University of Malaysia, Kuala Lumpur 57000, Malaysia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7543","container-title":["International Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"http:\/\/ies.ijo.cn\/en_publish\/2024\/3\/20240314.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T08:51:09Z","timestamp":1709023869000},"score":1,"resource":{"primary":{"URL":"http:\/\/ies.ijo.cn\/gjyken\/ch\/reader\/view_abstract.aspx?file_no=20240314&flag=1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,18]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3,18]]}},"URL":"https:\/\/doi.org\/10.18240\/ijo.2024.03.14","relation":{},"ISSN":["2222-3959","2227-4898"],"issn-type":[{"type":"print","value":"2222-3959"},{"type":"electronic","value":"2227-4898"}],"subject":[],"published":{"date-parts":[[2024,3,18]]}}}