{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T00:07:52Z","timestamp":1760746072827,"version":"build-2065373602"},"reference-count":0,"publisher":"Press of International Journal of Ophthalmology (IJO Press)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Ophthalmol"],"published-print":{"date-parts":[[2025,11,18]]},"abstract":"<jats:p>AIM: To investigate the ultrasonographic features of ciliary body mesectodermal leiomyomas (CBL).?\nMETHODS: Ultrasonographic data of 18 eyes from 18 patients with histopathologically confirmed CBL were analyzed, covering the period from March 2018 to February 2024. The study included 5 male and 13 female patients, aged 14-64y, with a mean age of 40.11\u00b113.54y. The following ultrasonographic features were evaluated: tumor base diameter, thickness, maximum base diameter-to-thickness ratio, shape, internal echogenicity, margin echogenicity, internal echo homogeneity, secondary changes, color Doppler flow imaging (CDFI) findings, and contrast-enhanced ultrasound (CEUS) characteristics.?\nRESULTS: Conventional ultrasound findings of the 18 CBL cases were as follows: 1) Tumor size: base diameter of (13.48\u00b14.74)\u00d7(11.57\u00b14.00) mm2, thickness of 7.70\u00b12.60 mm, and maximum base diameter-to-thickness ratio of 1.77\u00b10.36. 2) Shape: 14 cases (77.8%) were hemispherical, and 4 cases (22.2%) were irregular. 3) Internal echogenicity: the solid component of the tumor was hypoechoic in 16 cases (88.9%) and low-to-medium echogenic in 2 cases (11.1%). 4) Margin echogenicity: relatively hyperechoic with a \u201cring-shaped\u201d margin in 15 cases (83.3%) and isoechoic in 3 cases (16.7%; compared with internal echogenicity). 5) Internal echo homogeneity: homogeneous in 11 cases (61.1%) and heterogeneous in 7 cases (38.9%), with 6 cases (33.3%) among the 7 heterogeneous cases exhibiting cystic anechoic areas. 6) Secondary retinal detachment was observed in 4 cases (22.2%). CDFI revealed heterogeneous vascularity within the tumors, with blood flow signals ranging from minimal to marked. CEUS was performed in 14 patients: complete contrast agent perfusion was observed in 10 cases (71.4%), and partial perfusion was noted in 4 cases (28.6%). Additionally, 8 cases (57.1%) showed a rapid wash-in and slow wash-out pattern, while 6 cases (42.9%) demonstrated a rapid wash-in and rapid wash-out pattern.\nCONCLUSION: CBL exhibit relatively typical ultrasonographic features, which can provide valuable evidence for the clinical diagnosis and differential diagnosis of intraocular tumors.?<\/jats:p>","DOI":"10.18240\/ijo.2025.11.11","type":"journal-article","created":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T03:40:20Z","timestamp":1760672420000},"page":"2099-2105","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasonographic features of ciliary body mesectodermal leiomyoma"],"prefix":"10.18240","volume":"18","author":[{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Jun","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Feng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Bin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Li","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Clinical Center for Eye Tumors, Capital Medical University, Beijing 100730, China","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7543","container-title":["International Journal of 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