{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T04:03:39Z","timestamp":1784174619021,"version":"3.55.0"},"reference-count":0,"publisher":"Press of International Journal of Ophthalmology (IJO Press)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Ophthalmol"],"published-print":{"date-parts":[[2026,8,18]]},"abstract":"<jats:p>AIM: To investigate the long-term effects of mini-scleral lens wear on intraocular pressure (IOP) and anterior chamber angle (ACA) in patients with keratoconus (KCN).\nMETHODS: A convenience sampling method was adopted to enroll KCN patients between November 2023 and April 2024. All participants had a definitive KCN diagnosis and were eligible for mini-scleral lens fitting. Baseline optometric examinations included visual acuity measurement, objective and subjective refraction, and slit-lamp biomicroscopy. Mini-scleral lenses were fitted with trial lenses. Participants returned for a 3-month follow-up, where all examinations were repeated.\nRESULTS: Seventeen KCN patients (12 males) were enrolled, aged 20\u201353y with a mean age of 38.09\u00b112.86y. Mean IOP rose by 0.33\u00b11.60 mm Hg after mini-scleral lens wear, without statistical significance (P=0.525). The nasal ACA increased by 0.73\u00b0\u00b12.69\u00b0 (P=0.390), whereas the temporal ACA decreased by \u22121.46\u00b0\u00b13.10\u00b0 (P=0.152). In severe KCN cases, mean IOP elevated from 7.60\u00b10.96 to 8.60\u00b11.14 mm Hg after lens fitting. By contrast, mild-to-moderate KCN patients showed a slight IOP decline from 11.58\u00b12.50 mm Hg at baseline to 11.33\u00b12.42 mm Hg post-fitting. Females presented a statistically significant reduction in temporal ACA after lens wear (P=0.020). Older baseline age was negatively correlated with temporal ACA width (\u03b2=\u22120.719, P=0.041).\nCONCLUSION: Patients with advanced KCN face higher risks of IOP elevation after mini-scleral lens fitting. ACA changes induced by mini-scleral lenses vary by sector, with temporal angle narrowing being more prominent. Clinicians should closely monitor potential temporal angle narrowing, especially in female and older KCN patients during mini-scleral lens fitting.<\/jats:p>","DOI":"10.18240\/ijo.2026.08.08","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:06:34Z","timestamp":1784171194000},"page":"1510-1517","source":"Crossref","is-referenced-by-count":0,"title":["Impact of a three-month period of mini-scleral lens usage on intraocular pressure and the anterior chamber angle in patients with keratoconus"],"prefix":"10.18240","volume":"19","author":[{"name":"Department of Optometry, Rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran 1449614535, Iran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parvin","family":"Esmaili-Badrabadi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morad Amir","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Optometry, Department of Physiotherapy, Erbil Technical &amp; Medical Health Collage, Erbil Polytechnic University, Erbil, Kurdistan Region 44001, Iraq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdollah","family":"Farzaneh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Optometry, Rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran 1449614535, Iran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asgar","family":"Doostdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Optometry, Rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran 1449614535, Iran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbasali","family":"Yekta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Optometry, School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad 1394491388, Iran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahdi","family":"Mahmoodi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran 1983963113, Iran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Saeid","family":"Hoseinzade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran 1983963113, Iran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Khabazkhoob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran 1983969411, Iran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7543","container-title":["International Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.ijo.cn\/gjyken\/article\/pdf\/20260808","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:06:50Z","timestamp":1784171210000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ijo.cn\/gjyken\/article\/abstract\/20260808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,18]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8,18]]}},"URL":"https:\/\/doi.org\/10.18240\/ijo.2026.08.08","relation":{},"ISSN":["2222-3959","2227-4898"],"issn-type":[{"value":"2222-3959","type":"print"},{"value":"2227-4898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,18]]}}}