{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T04:03:39Z","timestamp":1784174619011,"version":"3.55.0"},"reference-count":0,"publisher":"Press of International Journal of Ophthalmology (IJO Press)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Ophthalmol"],"published-print":{"date-parts":[[2026,8,18]]},"abstract":"<jats:p>AIM: To investigate the intraocular pressure (IOP)-lowering efficacy of bleb-free ab interno trabeculectomy by means of the Kahook Dual Blade (KDB).\nMETHODS: This retrospective cohort study enrolled patients with uncontrolled open angle glaucoma (OAG) who underwent standalone KDB ab interno trabeculectomy. Changes in IOP, the number of preoperative and postoperative IOP-lowering medications, as well as intraoperative and postoperative surgical profiles were analyzed. All participants completed a 6-month follow-up. Arithmetic mean, standard deviation (SD) and frequency were calculated, and the Wilcoxon test was used for statistical analysis.\nRESULTS: A total of 23 participants (15 males) were included, with a mean age of 69.3\u00b19.6y. The baseline mean IOP was 21.7\u00b15.6 mm Hg, with patients taking an average of 3.1\u00b11.0 topical IOP-lowering medications, and 10 patients received adjuvant systemic acetazolamide preoperatively. At the 3-month follow-up, the mean IOP decreased to 12.7\u00b14.3 mm Hg, with a mean medication score of 2.9\u00b11.8. At the 6-month follow-up, mean IOP was reduced by 40.6% from the baseline level (P&lt;0.01), with a mean medication requirement of 2.8\u00b11.0; one-fifth of all participants discontinued glaucoma medications completely. Only mild postoperative hyphemata occurred in 10 cases, and no other surgery-related adverse complications were observed.\nCONCLUSION: Standalone ab interno trabeculectomy with KDB yields significant IOP reduction and favorable surgical safety in patients with uncontrolled OAG, meanwhile decreasing the requirement of topical IOP-lowering medications. Long-term therapeutic efficacy remains to be further validated. Distinct from previous published studies, this study focuses on a Caucasian population and confirms surgical efficacy of KDB as a single glaucoma procedure.<\/jats:p>","DOI":"10.18240\/ijo.2026.08.11","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:06:34Z","timestamp":1784171194000},"page":"1533-1538","source":"Crossref","is-referenced-by-count":0,"title":["Kahook Dual Blade: six-month results in uncontrolled open angle glaucoma"],"prefix":"10.18240","volume":"19","author":[{"name":"Augenklinik der Universit&#xE4;t Ulm, Prittwitzstrasse 43, Ulm 89075, Deutschland, Germany","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna Friederike","family":"Koenig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie Charlotte","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Augenklinik der Universit&#xE4;t Ulm, Prittwitzstrasse 43, Ulm 89075, Deutschland, Germany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Efstathios","family":"Vounotrypidis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Augenklinik der Universit&#xE4;t Ulm, Prittwitzstrasse 43, Ulm 89075, Deutschland, Germany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Augenklinik der Universit&#xE4;t Ulm, Prittwitzstrasse 43, Ulm 89075, Deutschland, Germany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armin","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Augenklinik der Universit&#xE4;t Ulm, Prittwitzstrasse 43, Ulm 89075, Deutschland, Germany","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7543","container-title":["International Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.ijo.cn\/gjyken\/article\/pdf\/20260811","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:06:56Z","timestamp":1784171216000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ijo.cn\/gjyken\/article\/abstract\/20260811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,18]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8,18]]}},"URL":"https:\/\/doi.org\/10.18240\/ijo.2026.08.11","relation":{},"ISSN":["2222-3959","2227-4898"],"issn-type":[{"value":"2222-3959","type":"print"},{"value":"2227-4898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,18]]}}}