{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T06:32:21Z","timestamp":1786689141148,"version":"build-2736575974"},"reference-count":0,"publisher":"Press of International Journal of Ophthalmology (IJO Press)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Ophthalmol"],"published-print":{"date-parts":[[2026,9,18]]},"abstract":"<jats:p>AIM: To compare the fluctuating characteristics, mean value and peak value of intraocular pressure (IOP) between medically and surgically controlled eyes in patients with primary open angle glaucoma (POAG) based on a 12-hour daytime diurnal curve (12-DDC) and water drinking test (WDT). Additionally, this study evaluated the consistency of 12-DDC outcomes measured on two separate days.\nMETHODS: This was a cross-sectional observational study. Eligible POAG patients with unilateral medically and contralateral surgically controlled IOP via functional augmented trabeculectomy bleb were enrolled. Diurnal IOP was detected every 3h from 8:00 a.m. to 8:00 p.m. over two consecutive days to establish the 12-DDC. The WDT was performed subsequent to the completion of diurnal IOP measurement.\nRESULTS: A total of 21 POAG patients were included, with a mean age of 65.5\u00b17.3y, predominantly male (n=17, 81.0%), and of Malay ethnicity (n=13, 61.9%). The medically controlled eyes exhibited significantly greater diurnal IOP fluctuation (4.6\u00b11.7 mm Hg) compared with surgically controlled eyes (3.0\u00b11.5 mm Hg, P=0.005). Similarly, the peak IOP derived from WDT was significantly higher in medically controlled eyes (19.6\u00b14.1 mm Hg) than in surgical counterparts (11.2\u00b13.4 mm Hg, P&amp;#x003C;0.001). A strong and significant positive correlation was identified between peak IOP values of 12-DDC and WDT. For surgically controlled eyes, 12-DDC measurements obtained on two different days showed excellent consistency at all corresponding time points, with Kappa values ranging from 0.88 to 0.95.\nCONCLUSION: Under the condition of consistent physiological background affecting IOP circadian variation in the same individual, surgically controlled eyes demonstrate a superior IOP profile with lower fluctuation and peak IOP compared with medically controlled eyes in POAG patients.<\/jats:p>","DOI":"10.18240\/ijo.2026.09.07","type":"journal-article","created":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T06:15:08Z","timestamp":1786688108000},"page":"1720-1730","source":"Crossref","is-referenced-by-count":0,"title":["Intraocular pressure profiles between ipsilateral surgically and contralateral medically-controlled in primary open angle glaucoma patients"],"prefix":"10.18240","volume":"19","author":[{"name":"Department of Ophthalmology, Hospital Sultanah Bahiyah, Kedah 05460, Malaysia; Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tze Suen","family":"Chow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rona Asnida","family":"Nasaruddin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenshen","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norshamsiah Md","family":"Din","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7543","container-title":["International Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.ijo.cn\/gjyken\/article\/pdf\/20260907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T06:15:10Z","timestamp":1786688110000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ijo.cn\/gjyken\/article\/abstract\/20260907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,18]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9,18]]}},"URL":"https:\/\/doi.org\/10.18240\/ijo.2026.09.07","relation":{},"ISSN":["2222-3959","2227-4898"],"issn-type":[{"value":"2222-3959","type":"print"},{"value":"2227-4898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,18]]}}}