{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T08:22:18Z","timestamp":1789114938113,"version":"build-2803163510"},"reference-count":0,"publisher":"Press of International Journal of Ophthalmology (IJO Press)","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Ophthalmol"],"published-print":{"date-parts":[[2026,10,18]]},"abstract":"<jats:p>AIM: To evaluate the impact of high-intensity light on ocular length and structural thickness in chick model of the early lens-induced myopia (LIM) by optical coherence tomography (OCT).\nMETHODS: Four-day-old chicks were monocularly covered with \u221210 D lenses for a period of 2d, exposed to either high-intensity light (HL, 10 000 lx) or normal-intensity light (NL, 500 lx) for 12h per day. A two-dimensional visualized swept-source OCT system was used to measure anterior chamber depth (ACD), lens thickness, vitreous chamber depth, axial length, retinal thickness and choroidal thickness. The refractive error was measured with retinoscopy.\nRESULTS: After 2d of treatment, the LIM eyes under NL condition experienced a greater myopic shift (P=0.028) and greater axial elongation (P=0.033) than those exposed to HL. ACD significantly increased in LIM eyes under NL condition when compared with baseline, while no statistical difference of ACD was found between day 2 and day 0 in LIM eyes under HL condition. LIM eyes all experienced the thinning of retinal thickness and choroidal thickness (all P&lt;0.05), with no statistically significant differences between NL and HL group.\nCONCLUSION: HL could reduce the development of LIM at an early stage. Under NL, hyperopic defocus appears to induce a deepening of ACD at the early stage; this effect could potentially be mitigated by HL. At an early stage, HL may have no significant effects on the changes in retinal and choroidal thickness in LIM eyes.<\/jats:p>","DOI":"10.18240\/ijo.2026.10.03","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T07:25:34Z","timestamp":1789111534000},"page":"1898-1905","source":"Crossref","is-referenced-by-count":0,"title":["Effects of high-intensity light on early lens-induced myopia in chicks: optical coherence tomography assessment"],"prefix":"10.18240","volume":"19","author":[{"name":"Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai 200031, China; Research Center of Ophthalmology and Optometry Shanghai, Shanghai 200031, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, Shanghai 200031, China","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luo-Li","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang-Yi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai 200031, China; Research Center of Ophthalmology and Optometry Shanghai, Shanghai 200031, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, Shanghai 200031, China","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Liang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai 200031, China; Research Center of Ophthalmology and Optometry Shanghai, Shanghai 200031, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, Shanghai 200031, China","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Liao","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai 200031, China; Research Center of Ophthalmology and Optometry Shanghai, Shanghai 200031, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, Shanghai 200031, China","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai 200031, China; Research Center of Ophthalmology and Optometry Shanghai, Shanghai 200031, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, Shanghai 200031, China","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing-Tao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai 200031, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai 200031, China; Research Center of Ophthalmology and Optometry Shanghai, Shanghai 200031, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care, Shanghai 200031, China","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7543","container-title":["International Journal of Ophthalmology"],"original-title":[],"link":[{"URL":"https:\/\/www.ijo.cn\/gjyken\/article\/pdf\/20261003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T07:25:35Z","timestamp":1789111535000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ijo.cn\/gjyken\/article\/abstract\/20261003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,18]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10,18]]}},"URL":"https:\/\/doi.org\/10.18240\/ijo.2026.10.03","relation":{},"ISSN":["2222-3959","2227-4898"],"issn-type":[{"value":"2222-3959","type":"print"},{"value":"2227-4898","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,18]]}}}