{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T10:50:29Z","timestamp":1758279029309,"version":"3.40.5"},"reference-count":38,"publisher":"Universidad Nacional de Lanus","license":[{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SCOL"],"abstract":"<jats:p>El s\u00edndrome de Down es la condici\u00f3n gen\u00e9tica m\u00e1s com\u00fan y una causa principal de discapacidad intelectual. Las personas en \u00e1reas rurales, especialmente aquellas con discapacidades, a menudo enfrentan desigualdades en el acceso a la salud. A partir de los registros cl\u00ednicos de pacientes con diagn\u00f3stico confirmado de s\u00edndrome de Down entre 2013 y 2022, por el Instituto de Gen\u00e9tica de la Universidad Mayor de San Andr\u00e9s, La Paz, Bolivia, se analiz\u00f3, analiz\u00f3 el tiempo hasta el diagn\u00f3stico de 250 pacientes con s\u00edndrome de Down, mostr\u00f3 que los pacientes procedentes de \u00e1reas rurales con s\u00edndrome de Down tardan cinco meses en promedio en recibir un diagn\u00f3stico, comparado a los dos meses en zonas urbanas (p&lt;0,001). No se encontraron diferencias significativas en el tiempo hasta el diagnostico seg\u00fan el sexo. Sin embargo, se evidenci\u00f3 una mayor proporci\u00f3n de varones provenientes de \u00e1reas rurales (p=0,03). Los hallazgos sugieren que los individuos de \u00e1reas rurales enfrentan dificultades para recibir el diagn\u00f3stico. Por otro lado, las mujeres quiz\u00e1s no sean llevadas a ciudades para un diagn\u00f3stico y tratamiento adecuado debido a sesgos de g\u00e9nero en ciertas comunidades. Se subraya la importancia de mejorar el acceso a diagn\u00f3sticos y tratamientos tempranos en \u00e1reas rurales.<\/jats:p>","DOI":"10.18294\/sc.2024.4710","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T22:28:43Z","timestamp":1710887323000},"page":"e4710","source":"Crossref","is-referenced-by-count":2,"title":["Desigualdades en el tiempo hasta el diagn\u00f3stico del s\u00edndrome de Down en Bolivia"],"prefix":"10.18294","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0560-1548","authenticated-orcid":false,"given":"Daniel","family":"Linares Terrazas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Luna Barr\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gonzalo","family":"Taboada L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"7901","published-online":{"date-parts":[[2024,3,19]]},"reference":[{"key":"21961","doi-asserted-by":"crossref","unstructured":"Bull MJ. 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