{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T11:49:24Z","timestamp":1793274564075,"version":"4.5.0"},"reference-count":0,"publisher":"Sultan Qaboos University","issue":"1","license":[{"start":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:00:00Z","timestamp":1747353600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sultan Qaboos University Medical Journal"],"abstract":"<jats:p>Symmetrical peripheral gangrene (SPG) is an exceptionally uncommon complication of malaria, predominantly linked with Plasmodium falciparum and mixed infections. We report a 41-year-old female who presented to a tertiary care centre of eastern India in 2022 with complaint of fever with chills and rigor for 4 days along with pain and acrocyanosis of distal portions of bilateral upper and lower limbs for last 2 days. Investigations revealed anaemia and neutrophilic leucocytosis with thrombocytopaenia. The peripheral smear revealed trophozoites of P. vivax and the malaria rapid diagnostic test confirmed the presence of P. vivax antigen. D-dimer and fibrin degradation product was elevated and prothrombin time and activated partial thromboplastin time were prolonged; arterial colour doppler of all 4 extremities were within normal limits. A diagnosis of P. vivax malaria was made complicated with disseminated intravascular coagulation leading to SPG.<\/jats:p>","DOI":"10.18295\/2075-0528.2842","type":"journal-article","created":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T12:36:17Z","timestamp":1747485377000},"page":"336-340","source":"Crossref","is-referenced-by-count":2,"title":["Symmetrical Peripheral Gangrene Associated with &lt;i&gt;Plasmodium Vivax&lt;\/i&gt; Malaria: &lt;em&gt;A case report with a brief review of literature&lt;\/em&gt;"],"prefix":"10.18295","volume":"25","author":[{"given":"Atanu","family":"Chandra","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Bankura Sammilani Medical College, Bankura, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koustav A.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, RG Kar Medical College and Hospital, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debapratim","family":"Ganguly","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Midnapore Medical College and Hospital, Midnapore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupak","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Tropical Medicine, Calcutta School of Tropical Medicine, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sugata","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, IPGMER and SSKM Hospital, Kolkata, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"7681","published-online":{"date-parts":[[2025,5,16]]},"container-title":["Sultan Qaboos University Medical Journal"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T11:17:33Z","timestamp":1793272653000},"score":1,"resource":{"primary":{"URL":"https:\/\/mjournal.squ.edu.om\/home\/vol25\/iss1\/50"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,16]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,5,16]]}},"URL":"https:\/\/doi.org\/10.18295\/2075-0528.2842","relation":{},"ISSN":["2075-0528"],"issn-type":[{"value":"2075-0528","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,16]]}}}